The efficacy of tonsillectomy on long-term renal survival in patients with IgA nephropathy

Abstract

These results indicate that tonsillectomy has a favorable effect on long-term renal survival in patients with IgAN.

Glomerular Diseases

“…One study of 55 patients with IgAN, of whom 16 had tonsillectomy, could find no independent benefit of the procedure .10 years after tonsillectomy (46). Another evaluated 118 patients with IgAN: 48 with prior tonsillectomy and 70 without (47). Renal survival at 240 months was 90% for the tonsillectomy group and 64% for the group without tonsillectomy, but no difference in renal survival was noted between the groups until 10 years from biopsy.…”

A case of synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome complicated by IgA nephropathy with nephrotic syndrome

“…A search of the literature using the PubMed system turned up only six reported cases of IgAN complicated with skin or bone disease, excluding the present case (Table 2) [16][17][18][19][20]. As pointed out by the authors of those studies, palmoplantar pustulosis and sternocostoclavicular hyperostosis, as well as IgAN, are associated with tonsillar infections, and tonsillectomies are an effective treatment of those diseases [21][22][23][24]. That suggests activation/dysfunction of the immune response to tonsillar infection may be an important etiology for those ailments.…”

Efficacy of Tonsillectomy Plus Methylprednisolone Pulse Therapy for a Child with Henoch-Schoenlein Purpura Nephritis

“…Recently, there have been reports on the efficacy of tonsillectomy for IgAN in adults (Sanai and Kudoh 1996;Hotta et al 2001;Xie et al 2003). Hotta et al reported that tonsillectomy plus methylprednisolone pulse therapy led to clinical remission in adult patients with IgAN (Hotta et al 2001).…”

“…Frequent association between upper respiratory tract infection and the development of HSP has also been suggested (Yoshikawa et al 1987;Habib et al 1994;Rai et al 1999). Recently, there have been reports of the efficacy of tonsillectomy and tonsillectomy plus methylprednisolone pulse therapy (tonsillectomy pulse therapy) in treating IgAN (Sanai and Kudoh 1996;Hotta et al 2001;Xie et al 2003). In addition, there had been a few reports on the efficacy of tonsillectomy pulse therapy for HSPN in adult (Sugiyama et al 2005).…”