The Efficacy of Various Degreasing Agents Used in Trichloroacetic Acid Peels

Peikert, Johann M.; Krywonis, Nancy A.; Rest, Ellen B.; Zachary, Christopher B.

doi:10.1111/j.1524-4725.1994.tb03193.x

Cited by 24 publications

(6 citation statements)

References 8 publications

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“…Firm pressure is applied during defatting to ensure complete stripping of the stratum corneum. There is evidence to support that the above may be accomplished with Hibiclens (19).…”

Section: Methodsmentioning

confidence: 99%

Chemical peeling in ethnic/dark skin

Roberts

2004

Dermatol Ther

115

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Chemical peeling for skin of color arose in ancient Egypt, Mesopotamia, and other ancient cultures in and around Africa. Our current fund of medical knowledge regarding chemical peeling is a result of centuries of experience and research. The list of agents for chemical peeling is extensive. In ethnic skin, our efforts are focused on superficial and medium-depth peeling agents and techniques. Indications for chemical peeling in darker skin include acne vulgaris, postinflammatory hyperpigmentation, melasma, scarring, photodamage, and pseudofolliculitis barbae. Careful selection of patients for chemical peeling should involve not only identification of Fitzpatrick skin type, but also determining ethnicity. Different ethnicities may respond unpredictably to chemical peeling regardless of skin phenotype. Familiarity with the properties each peeling agent used is critical. New techniques discussed for chemical peeling include spot peeling for postinflammatory hyperpigmentation and combination peels for acne and photodamage. Single- or combination-agent chemical peels are shown to be efficacious and safe. In conclusion, chemical peeling is a treatment of choice for numerous pigmentary and scarring disorders arising in dark skin tones. Familiarity with new peeling agents and techniques will lead to successful outcomes.

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“…Firm pressure is applied during defatting to ensure complete stripping of the stratum corneum. There is evidence to support that the above may be accomplished with Hibiclens (19).…”

Section: Methodsmentioning

confidence: 99%

Chemical peeling in ethnic/dark skin

Roberts

2004

Dermatol Ther

115

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“…Efficacy of the 4 agents was assessed by clinical and histologic examination, which showed no significant difference between treatments. These authors concluded that while acetone is one of the most common agents employed, its lack of superior efficacy and lower flashpoint argue against its widespread use, 31 although, of course, flashpoint is less relevant in chemexfoliation.…”

Section: Chemexfoliationmentioning

confidence: 99%

Skin Preparation for Photodynamic Therapy, Chemexfoliation, and Ablative Laser Resurfacing: a Systematic Literature Review

2021

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BACKGROUND Photodynamic therapy, chemexfoliation, and ablative laser resurfacing are common practices for dermatologists, yet no formal protocols exist regarding preprocedural skin preparation. OBJECTIVE To review and summarize the skin preparation protocols for photodynamic therapy, chemexfoliation, and ablative laser resurfacing available in the literature. METHODS Data Sources A systematic review of English and non-English articles using the PubMed database was performed. A manual search of bibliographies from relevant articles was also performed to collect additional studies. Study Selection Only articles in the English language with full texts available that pertained to skin preparation for photodynamic therapy, chemexfoliation, and ablative laser resurfacing were included. Data Extraction Article selection was performed by one author, and relevant sources were verified by other authors using predefined inclusion and exclusion criteria. RESULTS There is a paucity of scientific research regarding efficacy and safety of dermatologic preprocedural skin preparation agents. Only 2 studies have compared various cleansing agents for these measures. Yet, strong statements regarding the importance of degreasing are published without supportive data. CONCLUSION Consensus guidelines for preprocedural protocols are lacking for photodynamic therapy, chemexfoliation, and ablative laser resurfacing. Further studies are warranted to explore the efficacy and safety of various preprocedural cleansing agents.

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“…Vor-und Nachbehandlung sind ausschlaggebend für das Peelergebnis. Mit tretinoinhaltigen Cremes werden der Fettgehalt und der pH-Wert der Haut vor dem Peel gesenkt [32,39], die Korneozytenadhäsion wird verringert und die Epidermolyse gefördert, damit sich die Wirkung der Peelsubstanz gleichmäßig in Epidermis und Dermis entfalten kann. Tretinoin bewirkt außer-dem eine erhöhte Mitoserate der Keratinozyten und gewährleistet eine kürze-re Reepithelialisierungsphase nach dem Peel [30,32].…”

Section: Vorbehandlung Für Chemical Peelsunclassified

Chemical Peels in der �sthetischen Dermatologie

Wiest¹

2004

Hautarzt

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Chemical peels are classified as very superficial (exfoliation), superficial (epidermal), medium (papillary dermal) and deep (reticular dermal). A successful peel depends upon a number of variables, such as choice of the peeling agent, its concentration, and the pressure and frequency of the applications; all must be adjusted to the patient's skin condition. Through standardization of the peeling agents, the level of injury can be determined pre-operatively and complications minimized. Trichloroacetic acid (TCA) is the most popular peeling agent used in different concentrations. It has the broadest spectrum of indications due to its versatility in combination with other peeling agents. Indications for superficial peels include skin resurfacing, wrinkles, actinically damaged skin, actinic keratoses and benign pigmented lesions. Superficial peels have the advantage that they can be used on most regions of the body. The use of different chemical peels, their varying effects and their potential complications are reviewed. There are at present more than 45 chemical peels with different combinations of agents available on the European market.

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The Efficacy of Various Degreasing Agents Used in Trichloroacetic Acid Peels

Abstract: Acetone was not found to be superior to the other agents. Furthermore, the flashpoint of acetone is markedly lower than the others, making it more flammable and hazardous in the workplace. The use of alternative degreasers may lessen or eliminate this hazard.

Cited by 24 publications

References 8 publications

Chemical peeling in ethnic/dark skin

Chemical peeling in ethnic/dark skin

Skin Preparation for Photodynamic Therapy, Chemexfoliation, and Ablative Laser Resurfacing: a Systematic Literature Review

Chemical Peels in der �sthetischen Dermatologie

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