The eighth edition American Joint Committee on Cancer (AJCC) melanoma staging system: implications for melanoma treatment and care

Keung, Emily Z.; Gershenwald, Jeffrey E.

doi:10.1080/14737140.2018.1489246

Cited by 382 publications

(309 citation statements)

References 71 publications

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“…Mucinous adenocarcinoma was featured by invasive peritoneal lesions comprised with abundant glandular or signet ring cell morphology epithelium with sufficient architectural complexity and cytological atypia to a diagnosis confirmation of mucinous carcinoma. The diagnosis criteria were according to the 8th Edition of American Joint Committee on Cancer [7]. The exclusion criteria were as follows: 1.…”

Section: Patientsmentioning

confidence: 99%

“…According to the 8th edition of the American Joint Committee on Cancer (AJCC) Staging Manual, mucinous adenocarcinomas of the appendix are classified into low-grade and high-grade (well-differentiated and moderately/poorly differentiated, respectively) tumor based on histological grade in the AJCC TNM Staging System [5][6][7]. Due to the low incidence, lacking of available data about the prognostic factors for appendix mucinous adenocarcinomas and non-adenocarcinomas in current clinical practice.…”

Section: Introductionmentioning

confidence: 99%

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Management and prognostic prediction of appendiceal mucinous adenocarcinoma with peritoneal metastasis: a single center study in China

Wang

Zhai

et al. 2020

BMC Cancer

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Background: To investigate the clinical and pathological characteristics of appendiceal mucinous adenocarcinoma with peritoneal metastasis and analyze the prognostic factors. Methods: A retrospective analyses of clinicopathological features of 50 patients with appendiceal mucinous adenocarcinoma with peritoneal metastasis from January, 2013 to December, 2017 in Aerospace Central Hospital, Beijing, China. Survival data calculation and comparison were respectively performed with the Kaplan-Meier method and the log-rank test. The Cox proportional hazards regression method was used for multivariate survival analyses. Results: Cytoreduction for appendiceal mucinous adenocarcinoma was conducted on 50 patients (24 males and 26 females), with a median age of 52.5 years at the time of surgery (range 31-71 years). The median overall survival (OS) time was 24 months, with 2-,3-and 5-year survival rates of 53, 24 and 8%, respectively. At the last follow-up in December 2018, 13 patients were still alive. Multivariate analysis revealed that patients who had low Ki-67 expression (less than 50%) and CCR (completeness of cytoreduction) 0/1/2 score had significantly better OS rate than their respective counterparts. Conclusions: Ki-67 expression statue and CCR score could be employed as the prognosis prediction in patients with appendiceal mucinous adenocarcinoma.

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Section: Patientsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Management and prognostic prediction of appendiceal mucinous adenocarcinoma with peritoneal metastasis: a single center study in China

Wang

Zhai

et al. 2020

BMC Cancer

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“…According to the 8 th edition of the American Joint Committee on Cancer (AJCC) Staging Manual, mucinous adenocarcinomas of the appendix are classified into low-grade and high-grade (welldifferentiated and moderately/poorly differentiated, respectively) tumor based on histological grade in the AJCC TNM Staging System [5][6][7]. Due to the low incidence, lacking of available data about the prognostic factors for appendix mucinous adenocarcinomas and non-adenocarcinomas in current clinical practice.…”

mentioning

confidence: 99%

Management and Prognostic Prediction of appendiceal mucinous adenocarcinoma with peritoneal metastasis: a single center study in China

Wang

Zhai

et al. 2019

Preprint

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Background To investigate the clinical and pathological characteristics of appendiceal mucinous adenocarcinoma with peritoneal metastasis and analyze the prognostic factors.Methods A retrospective analyses of clinicopathological features of 50 patients with appendiceal mucinous adenocarcinoma with peritoneal metastasis from January, 2013 to December, 2017 in Aerospace Central Hospital, Beijing, China. Survival data calculation and comparison were respectively performed with the Kaplan-Meier method and the log-rank test. The Cox proportional hazards regression method was used for multivariate survival analyses.Results Cytoreduction for appendiceal mucinous adenocarcinoma was conducted on 50 patients (24 males and 26 females), with a median age of 52.5 years at the time of surgery (range 31-71 years). The median overall survival (OS) time was 24 months, with 2-,3- and 5-year survival rates of 53%, 24% and 8%, respectively. At the last follow-up in December 2018, 13 patients were still alive. Multivariate analysis revealed that patients who had low Ki-67 expression (less than 50%) and CCR (completeness of cytoreduction) 0/1/2 score had significantly better OS rate than their respective counterparts.Conclusions Ki-67 expression statue and CCR score could be employed as the prognosis prediction in patients with appendiceal mucinous adenocarcinoma.

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“…Facial units understanding, fine handling, meticulous surgery, care of relaxing skin tension lines, choice of certain techniques, and designs for the flaps are crucial factors in the reconstruction of the defects after lesion excision from the face…”

Section: Discussionmentioning

confidence: 93%

Facial skin cancer reconstructive and cosmetic outcomes: Analysis with algorithm for its management

Ali

Mohamed

Nasef

et al. 2019

J of Cosmetic Dermatology

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Background: Management of facial skin cancer and its complications is important research topics needing continuous update to improve the outcome. Objective:The study is to share our findings with surgeons and healthcare providers.The authors provide their efforts by pooling data from multiple institutions; as reporting surgical outcomes is significantly lacking and much needed in the Middle East and North Africa region in order to meaningfully improve quality of care. This study proposes an algorithm for management that could aid a surgical decision-making for reconstruction of defects after excision of facial skin cancer. Methods:Retrograde simple descriptive analysis study is conducted for multicenter data about management of facial skin cancer and its cosmetic outcome. The analysis involves 159 male patients and 95 females.Results: Nonmelanoma skin cancer was reported in 250 (98.4%) of 254 cases.Reconstructive procedures were complicated in 16 cases (~6.3% of the study). Skin cancer recurrence in head and neck has happened in five cases (~1.9% of the study).Flaps used survived without major complications; however, V-Y advancement flaps showed the best aesthetic outcome. Conclusion:This study reports data in order to meaningfully improve the quality of care. Disease incidence, reconstructive complications, recurrences, and aesthetic outcome of facial skin cancer are included in the study. Based on the data pooling, the study proposes a simple treatment algorithm that could aid in surgical decisionmaking. V-Y advancement flaps showed the best aesthetic outcome. K E Y W O R D Saesthetic, algorithm, face, multicenters, skin cancer | INTRODUC TI ONSkin cancer is classified into melanoma and nonmelanoma types. 1,2 Incidence of each type varies according to a genetic, predisposing, 3 ethnic, or geographic factor. 4 In management of facial, scalp, and neck skin cancer, surgery always has a basic contribution. 5 Surgeons and dermatologists have many choices for the closure of the defects after excision, according to each lesion; site and size, patient age skin elasticity, in addition to individual experience and understanding of facial proportion. 6,7

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The eighth edition American Joint Committee on Cancer (AJCC) melanoma staging system: implications for melanoma treatment and care

Cited by 382 publications

References 71 publications

Management and prognostic prediction of appendiceal mucinous adenocarcinoma with peritoneal metastasis: a single center study in China

Management and prognostic prediction of appendiceal mucinous adenocarcinoma with peritoneal metastasis: a single center study in China

Management and Prognostic Prediction of appendiceal mucinous adenocarcinoma with peritoneal metastasis: a single center study in China

Facial skin cancer reconstructive and cosmetic outcomes: Analysis with algorithm for its management

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