The emerging role of dark berry polyphenols in human health and nutrition

Abstract

Dark berry fruits are one of the top 10 richest sources of dietary polyphenols and have been examined for their pharmacokinetic benefits in the human body related to absorption, digestion, metabolism, and excretion (ADME). With the expansion of the world wide web and rise of discretionary income in Europe and North America impacting the global food trade during the 21st century, several species of berries have become available for general consumption that may have previously been out of reach of the average consumer. Compared to their commercial counterparts, these berries contain many of the same polyphenols, and the possibility exists for the discovery of novel phenolic compounds that may affect the ADME process in a host-beneficial way.Several species have demonstrated antioxidant, antiobesogenic, antimicrobial, and anti-inflammatory properties through in vitro, animal studies, and human clinical trials. This review examines the available chemical compositions of several dark berries and their effect on the ADME process, their implication in host health effects, and the potential of these emerging species to suggest areas for future research.

Toxicity of zearalenone and its nutritional intervention by natural products

“…In recent years, numerous natural compounds, including dietary supplements that can alleviate ZEN-induced systemic toxic effects, have received much attention from researchers. [164][165][166] Some of them are listed in Table 2. Most of the effective compounds that alleviate the toxic effects of ZEN-induced endocrine disrupting effects and oxidative stress have antioxidant activities; for instance, resveratrol, saffron, and vitamin E (Fig.…”

Proteomic analyses revealed the antibacterial mechanism of Aronia melanocarpa isolated anthocyanins against Escherichia coli O157: H7

“…Therefore, there is an urgent need for researchers to develop effective new antimicrobial agents to prevent and control the spread of foodborne pathogens. Many studies have focused on natural plant extracts, including essential oils and phenols, which are considered the most promising candidates for natural antibiotics ( Moreira Gonçalves et al, 2020 ; Alexandrino et al, 2021 ; Higbee et al, 2022 ; Elwira et al, 2020 ).…”

Formation and metabolism of 6-(1-acetol)-8-(1-acetol)-rutin in foods and in vivo, and their cytotoxicity

“…Phenolic compounds are among the most applied natural compounds owing to their effective scavenging capacity of carbonyl compounds and other hazardous derivatives ( 16 – 18 ), in accompany with their distinguished physiological benefits ( 19 – 21 ). The flavonoids with typical meta -phenol structures possess efficient scavenging capacity for MGO.…”