The enhancement method of optical fiber biosensor based on surface plasmon resonance with cold plasma modification

Surface Plasmon Resonance‐Based Fiber Optic Sensors: Principle, Probe Designs, and Some Applications

“…The advantage of side-polished half block SPR sensor is that it requires a very small amount of sample for measuring the refractive index. Recently SPR-based side-polished multimode optical fiber sensors have been reported [33,34]. In these sensors the fiber was side-polished until half the core was closed.…”

“…Surface plasmon resonance-based fiber optic sensors have also been reported for other chemical species. These include measurements of salinity in water [22,37], refractive indices of alcohols [17], BSA [34], vapor and liquid analyses [18]. In addition a single-mode waveguide surface plasmon resonance sensor has been developed for biomolecular interaction analysis [47].…”

Optical fiber sensor based on surface plasmon resonance for rapid detection of avian influenza virus subtype H6: Initial studies

“…This low temperature plasma surface modification method has been used in the past for biomaterial surface modification with better biocompatibility and expected to be one of our solutions to solve this question. With the experience in surface modification using plasma treatment for several years (Lin et al, 2008;Zhao et al, 2015), we developed the optimal condition with the cold plasma modification on optical fiber sensor. The result showed that in the case of our optical fiber sensor, the cold plasma modification method was fast, uniform and more easily regulated than chemical surface modification, and the better immobilization was also demonstrated in one of our published paper (Lin et al, 2008).…”

“…With the experience in surface modification using plasma treatment for several years (Lin et al, 2008;Zhao et al, 2015), we developed the optimal condition with the cold plasma modification on optical fiber sensor. The result showed that in the case of our optical fiber sensor, the cold plasma modification method was fast, uniform and more easily regulated than chemical surface modification, and the better immobilization was also demonstrated in one of our published paper (Lin et al, 2008). The detection limit of the SPR optical fiber sensor for A/chicken/Taiwan/2838V/00 was 5.14 × 10 5 EID 50 /0.1 mL.…”

“…In this study, the optimal thickness of gold thin film on the polishing surface was approximately 40 nm, according to scanning electron microscope (Tokyo, Japan) observations, and the film was deposited using the DC sputtering system (20 mA and 5 W). The sensor output the SPR response spectrum, which was processed by considering a high detection limit for biomolecular interaction dynamics (Lin et al, 2007a;Lin et al, 2008).…”