2016
DOI: 10.4028/www.scientific.net/kem.675-676.77
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The Entrapment of Vitamin E in Nanostructured Lipid Carriers of Rambutan Seed Fat for Cosmeceutical Uses

Abstract: The aim of the present work was to extract the seed fat of Rambutan (Nephelium lappaceum L.) for developing nanostructured lipid carriers. Effect of material: solvent ratio and material size time on fat content were investigated. Nanostructured lipid carriers were prepared by melt-emulsification technique. Stearic acid (SA) and the rambutan seed fat (RF) was used as solid and liquid lipid, respectively. Surfactant was Tween 20 as well as Vitamin E was entrapment chemical. Effect of surfactant concentration on … Show more

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Cited by 7 publications
(10 citation statements)
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“…These authors observed that the particle size and the polydispersity index (PDI) of the particles containing VE decreased significantly with the increase of surfactant amount. In this research, 5% (w/w) Tween 20 was enough to produce particles with a mean diameter of 139.43 nm and PDI of 0.165 . Another study, by Chen and others (2017), described the same effect using Tween 80, in concentrations between 2 and 4% (w/w), to prepare nanoparticles of vitamin E with cetyl palmitate as solid lipid and sesame oil as liquid lipid.…”
Section: Resultsmentioning
confidence: 60%
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“…These authors observed that the particle size and the polydispersity index (PDI) of the particles containing VE decreased significantly with the increase of surfactant amount. In this research, 5% (w/w) Tween 20 was enough to produce particles with a mean diameter of 139.43 nm and PDI of 0.165 . Another study, by Chen and others (2017), described the same effect using Tween 80, in concentrations between 2 and 4% (w/w), to prepare nanoparticles of vitamin E with cetyl palmitate as solid lipid and sesame oil as liquid lipid.…”
Section: Resultsmentioning
confidence: 60%
“…A derived of vitamin E, tocopheryl acetate, was formulated in a lipid nanoparticle‐based product, while alpha‐tocopherol, the most abundant in nature and the most active form of the vitamin E family of compounds, was included in several types (SLN and NLC) of solid lipid nanoparticles. Particularly, in the past two years, NLC is being used more for vitamin E due to the better retention of the encapsulated substance . The most used solid lipids to encapsulate vitamin E are glyceryl monostearate, glyceryl behenate, cetyl palmitate, and stearic acid, while the most common lipid liquids are oleic acid and MCT.…”
Section: Introductionmentioning
confidence: 99%
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“…Niculae et al . found that different surfactants can form particles with different diameters, while several authors agree that smaller particles and lower PDIs are obtained with increasing surfactant concentration . An increase in mean particle diameter and PDI was associated with higher proportion of vitamin E by Ying et al .…”
Section: Characterization Of Slns/nlcs Loaded With Vitamin Ementioning
confidence: 93%
“…Kim et al [52] had similar results in relation to the proportion of liquid lipid. Niculae et al [32] found that different surfactants can form particles with different diameters, while several authors agree that smaller particles and lower PDIs are obtained with increasing surfactant concentration [17,29]. An increase in mean particle diameter and PDI was associated with higher proportion of vitamin E by Ying et al [51] and with higher levels of total lipid phase by Ma et al and Chen et al [17,50].…”
Section: Particle Sizementioning
confidence: 98%