The Enzymatic Regulatory Effects of Laninaria japonica Fucoidan Extract in Hepatotoxicity

Ha, Bae Jin; 강금석,; 남천석,; 박은경,

doi:10.5352/jls.2006.16.7.1104

Cited by 7 publications

(2 citation statements)

References 12 publications

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“…Soluble include alginates, insoluble cellulose (alguleza) [9,10,11]. Today, Japanese kelp is a priority among the raw materials for the production of functional and therapeutic and prophylactic food products in view of the unique combination of soluble and insoluble dietary fiber, as well as the mass of phytoparapharmaceuticals [12,13,14].…”

Section: Introductionmentioning

confidence: 99%

A study of the influence of the method of pretreating Japanese kelp on its quality

Dementieva

Boytsova

Sakharova

et al. 2022

IOP Conf. Ser.: Earth Environ. Sci.

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One of the ways to create functional foods is to fortify them with dietary fiber. Dietary fiber includes a large group of compounds that must be an integral part of the daily diet of people. Raw materials of marine origin containing dietary fiber are brown algae. For example, Japanese kelp, along with important biologically active substances, contains soluble and insoluble dietary fibers. Soluble fibers include alginates, insoluble – cellulose (alguleza). A common disadvantage of different methods of processing the kelp is the loss of important functional nutrients: organic and mineral substances. The choice of the correct modes of primary processing the algae will contribute to obtaining a high quality semi-finished product and the production of a wide range of food products based on it. A method has been developed for the primary processing of the kelp, which contributes to the improvement of organoleptic characteristics and ensures the preservation of physiologically important components of algae. The organoleptic and chemical characteristics of kelp after primary processing have been studied.

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Section: Introductionmentioning

confidence: 99%

A study of the influence of the method of pretreating Japanese kelp on its quality

Dementieva

Boytsova

Sakharova

et al. 2022

IOP Conf. Ser.: Earth Environ. Sci.

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“…Laminaria japonica (LJ) is a popular, edible, brown seaweed that is present in high quantities on Jeju Island, Korea [14]. In general, LJ contains soluble fibers, such as alginate and fucoidan, as well as fat-soluble components, such as fucoxanthin and fucosterol, along with minerals such as magnesium, iodine, calcium, iron, and zinc [15,16]. Its biological functions have been extensively investigated in both in vitro and in vivo models.…”

Section: Introductionmentioning

confidence: 99%

Laminaria japonica Extract Enhances Intestinal Barrier Function by Altering Inflammatory Response and Tight Junction-Related Protein in Lipopolysaccharide-Stimulated Caco-2 Cells

et al. 2019

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In the normal physiological state, intestinal epithelial cells act as a defensive frontline of host mucosal immunity to tolerate constant exposure to external stimuli. In this study, we investigated the potential anti-inflammatory and gut permeability protective effects of Laminaria japonica (LJ) water extract (LJE) and three types of fermented Laminaria japonica water extracts (LJE-F1, LJE-F2, and LJE-F3) in lipopolysaccharide (LPS)-stimulated Caco-2, human intestinal epithelial cells. All four extracts significantly decreased the production of nitric oxide and interleukin-6 induced by LPS stimulus. In addition, LJE and the three types of LJE-Fs also inhibited LPS-induced loss of monolayer permeability, as assessed by changes in transepithelial electrical resistance. All four LJ extracts significantly prevented the inhibition of the protein levels of occludin, whereas LJE, LJE-F1, and LJE-F3 significantly attenuated the reduction in phosphorylation of adenosine monophosphate-activated protein kinase compared with the LPS-treated group in Caco-2 cells. In conclusion, LJE and its fermented water extracts appear to have potential gut health-promoting effects by reducing inflammation and partially regulating the tight junction-related proteins in human intestinal epithelial cells. Thus, additional studies are warranted to evaluate Laminaria japonica as a therapeutic agent for inflammatory bowel diseases.

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Polysaccharide (laminaran and fucoidan), fucoxanthin and lipids as functional components from brown algae (Padina tetrastromatica) modulates adipogenesis and thermogenesis in diet-induced obesity in C57BL6 mice

Sharma

Baskaran

2021

Algal Research

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The Enzymatic Regulatory Effects of Laninaria japonica Fucoidan Extract in Hepatotoxicity

Cited by 7 publications

References 12 publications

A study of the influence of the method of pretreating Japanese kelp on its quality

A study of the influence of the method of pretreating Japanese kelp on its quality

Laminaria japonica Extract Enhances Intestinal Barrier Function by Altering Inflammatory Response and Tight Junction-Related Protein in Lipopolysaccharide-Stimulated Caco-2 Cells

Polysaccharide (laminaran and fucoidan), fucoxanthin and lipids as functional components from brown algae (Padina tetrastromatica) modulates adipogenesis and thermogenesis in diet-induced obesity in C57BL6 mice

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