The Epidemiology, Diagnosis, and Cost of Dyspepsia and <i><scp>H</scp>elicobater pylori</i> Gastritis: A Case–Control Analysis in the <scp>S</scp>outhwestern <scp>U</scp>nited <scp>S</scp>tates

Mapel, Douglas W.; Roberts, Melissa H.; Overhiser, Andrew; Mason, Andrew C.

doi:10.1111/j.1523-5378.2012.00988.x

Cited by 23 publications

(17 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It can be due to diverse contributing factors including socioeconomic status, geographical or living conditions, and ethnicity or location of each population ( 1 ). Dyspepsia is a medical condition characterized by chronic or recurrent pain in the upper abdomen, which is considered as one of the most common causes of patients’ referrals to gastroenterology centers ( 15 ).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Prevalence of Helicobacter pylori in Patients With Dyspepsia

Niknam

Seddigh

Fattahi

et al. 2014

Jundishapur J Microbiol

View full text Add to dashboard Cite

Background:The prevalence rate of gastric infections caused by Helicobacter pylori is different in between as well as within various countries, including Iran.Objectives:This study was aimed to evaluate the prevalence of H. pylori in Iranian adult patients with dyspepsia.Patients and Methods:A total of 548 patients with dyspepsia referred to Namazi Hospital, a referral center for gastrointestinal diseases in Shiraz, south of Iran, were evaluated in a cross-sectional study. The diagnosis of dyspepsia was based on clinical findings. Upper gastrointestinal endoscopy was performed for all the patients and two antral biopsies were taken from all the included ones. The patients were categorized based on the endoscopic findings, to four groups:normal,abnormal nonulcerative,ulcerative, andcombination of 2 and 3.Two positive test results (Gram staining, rapid urease test, and culture) was considered as a positive-definite H. pylori infection for each patient.Results:From the 548 included patients (238 males and 310 females), H. pylori was detected in 170 (31.2%). The mean age was 40.38 ± 15.39 years old. H. pylori infection was detected in 26.1% of male and 34.8% of female patients and its prevalence increased with age. Eighty three (48.8%) patients were positive for H. pylori infection, of which, 12.4% had normal and 36.4% had abnormal nonulcerative endoscopic findings; 17.1% of patients were ulcerative and 34.1% had ulcer with or without concurrent abnormality.Conclusions:Findings from this study showed a lower prevalence of H. pylori infection than other studies and its prevalence increased with age. There was no association between sex and infection. The most common endoscopic abnormality in H. pylori-positive patients was ulcerative lesion.

show abstract

Section: Introductionmentioning

confidence: 99%

“…In the western world, the reported prevalence of dyspepsia ranged 25-50% ( 17 , 18 ). In the south-western United States, dyspepsia and H. pylori -related gastrointestinal diagnoses were remarkably common, with an annual incidence of 13 per 1000 individuals ( 15 ).…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Helicobacter pylori in Patients With Dyspepsia

Niknam

Seddigh

Fattahi

et al. 2014

Jundishapur J Microbiol

View full text Add to dashboard Cite

show abstract

“…(27) Other studies have replicated these racial and ethnic disparities and have additionally shown differences in seroprevalence by sex, whereby women were at higher risk for H. pylori seropositivity. (28)…”

Section: Introductionmentioning

confidence: 99%

Helicobacter pylori Seropositivity and Cognitive Performance Among US Adults

Beydoun

Shroff

et al. 2013

Psychosomatic Medicine

View full text Add to dashboard Cite

Background Helicobacter pylori (H. pylori) seropositivity is a potential risk for poor cognition among US adults. Methods Cross-sectional data from the National Health and Nutrition Examination Survey III, phase 1 (1988–91) were used. Measures included age-group specific neuropsychological test batteries and two measures of H. pylori seropositivity (IgG and IgG-CagA) (20–59yo:n=2,090–2,248; 60–90yo:n=2,123–2,388). We explored sex- and race-specific associations. Results On the basis of multiple OLS and zero-inflated Poisson regression models, we detected a poorer performance among those 60–90yo with H. pylori IgG+ vs. IgG− on a verbal memory test (story recall, correct items), overall (β=−0.04±0.01, p=0.010). NH blacks and women (20–59yo) performed worse on the serial digits learning errors (SDL-TE) when H. pylori IgG+(vs. IgG−), another verbal memory test (β=+0.94±0.40, p=0.029 and β=+1.19±0.44, p=0.012, respectively); (p<0.10 for interaction by sex and race). More trials to completion on this test (SDL-TTC) were also required among H. pylori IgG+ overall (20–59yo, β=+0.30±0.13, p=0.033). Other race-specific associations without significant interaction by race that were detected in the same direction of worse performance with seropositivity included H. pylori IgG+ in NH blacks with the symbol digits substitution test-number of errors (SDS-E) (20–59yo, p=0.038) and with the incorrect items on the orientation test (ORIENT-INC) (60–90yo, p=0.038). H. pylori IgG CagA+ was associated with poorer Word Recall test performance(WR-CORR) among Mexican Americans(60–90yo, p=0.048), WR-TRIALS among NH whites(60–90yo, p=0.047) and ORIENT-INC among NH blacks(60–90yo, p=0.025). Conclusions H. pylori seropositivity markers were associated with poor cognition among US adults. Longitudinal research is needed to extrapolote those findings to cognitive decline, incident dementia and Alzheimer’s Disease.

show abstract

“…1,2 A recent systematic review reported a pooled prevalence of uninvestigated dyspepsia (defined according to Rome II criteria) of 19.0% (95% confidence interval 11.6-27.7%). 3 Functional dyspepsia poses a high financial burden on health systems 4 and is associated with important impairment in health-related quality of life. 5 According to Rome III criteria, FD is defined as the presence of chronic (>3 months) dyspeptic symptoms in the absence of underlying structural or metabolic disease that readily explains the symptoms.…”

mentioning

confidence: 99%