The epidemiology of microscopic colitis: a 10-year pathology-based nationwide Danish cohort study

Bonderup, Ole K.; Wigh, Tatjana; Nielsen, Gunnar Lauge; Pedersen, Lars; Fenger‐Grøn, Morten

doi:10.3109/00365521.2014.940378

Cited by 86 publications

(52 citation statements)

References 17 publications

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“…The incidence of MC in a recent Danish population-based study was found to have markedly increased from 4.6 per 100,000 persons in 2002 to 24.7 per 100,000 persons by the end of 2011 (23). Similarly, a population-based study from Olmsted County, Minnesota found that incidence of MC increased from 1.1 per 100,000 persons in the late 1980s to 19.6 per 100,000 persons by the end of 2001 (24).…”

Section: Epidemiology Of MCmentioning

confidence: 99%

Biomarkers and Microscopic Colitis: An Unmet Need in Clinical Practice

et al. 2017

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One of the most common causes of chronic diarrhea is ascribed to microscopic colitis (MC). MC is classified in subtypes: collagenous colitis (CC) and lymphocytic colitis (LC). Patients with MC report watery, non-bloody diarrhea of chronic course, abdominal pain, weight loss, and fatigue that may impair patient’s health-related quality of life. A greater awareness, and concomitantly an increasing number of diagnoses over the last years, has demonstrated that the incidence and prevalence of MC are on the rise. To date, colonoscopy with histological analysis on multiple biopsies collected along the colon represents the unique accepted procedure used to assess the diagnosis of active MC and to evaluate the response to medical therapy. Therefore, the emerging need for less-invasive procedures that are also rapid, convenient, standardized, and reproducible, has encouraged scientists to turn their attention to the identification of inflammatory markers and other molecules in blood or feces and within the colonic tissue that can confirm a MC diagnosis. This review gives an update on the biomarkers that are potentially available for the identification of inflammatory activity, related to CC and LC.

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Section: Epidemiology Of MCmentioning

confidence: 99%

Biomarkers and Microscopic Colitis: An Unmet Need in Clinical Practice

et al. 2017

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“…Initially considered a rare disease, several epidemiological studies reported an increasing incidence over time with similar incidence rate of Crohn's disease or ulcerative colitis, especially in women and elderly patients . However, both regional and nationwide studies have often shown heterogenous results in terms of incidence rate, trends and distribution among collagenous colitis (CC) and lymphocytic colitis (LC), the two main subtypes of MC (Table ).…”

Section: Epidemiological Studies On Microscopic Colitismentioning

confidence: 99%

Editorial: the increasing burden of microscopic colitis

Guagnozzi

Tontini

Pastorelli

2019

Aliment Pharmacol Ther

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“…The incidence of MC had been increasing over time,2 although recent population-based studies revealed a stabilisation of incidence at 21.0–24.7 cases per 100 000 person-years 3 4. The spectrum of MC ranges from mild self-limited episodes to severe medically refractory symptoms, without increased risk of mortality or colorectal cancer 1 5.…”

Section: Introductionmentioning

confidence: 99%