The evolution of white matter disease as seen on computed tomography.

Barnes, D.; Enzmann, Dieter R.

doi:10.1148/radiology.138.2.7455118

Cited by 32 publications

(17 citation statements)

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“…MR consistently depicted more lesions per patient than did CT in this category of patients. This sensitivity of long TR images is well described in the MR literature, [7] and as is also apparent from the CT and pathologic literature, [8] the dysmyelinating disorders demonstrated diffuse confluent high signal intensity in the white matter on long TR spin-echo images. We did not have any patients with a biochemically or biopsy-proved dysmyelinating disorder with patchy or focal white matter changes.…”

Section: Discussionsupporting

confidence: 59%

Paediatric White Matter Disorders: Mri and Ct Correlation

Ayesha¹,

Gonegandla²,

Raviraja³

et al. 2016

jemds

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BACKGROUNDWhite matter disorders or leukoencephalopathies comprise all disorders that exclusively or predominantly affect the white matter of the brain. There are many different leukoencephalopathies, which can occur at all ages, be progressive or static and be genetic or acquired. [1] Leukodystrophies are genetically determined leukoencephalopathies. The diagnostic workup is complicated. MRI has proven to be pivotal in the diagnostic workup of patients with leukoencephalopathies. [2]

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Section: Discussionsupporting

confidence: 59%

Paediatric White Matter Disorders: Mri and Ct Correlation

Ayesha¹,

Gonegandla²,

Raviraja³

et al. 2016

jemds

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“…On follow-up scans, the increased density in the thalami persisted as white-matter abnormalities, and atrophy appeared ( figs. 1 , 2, and 4) [5].…”

Section: Resultsmentioning

confidence: 98%

“…The etiology of symmetric density on CT has not been explained histologically, but it could represent transient alteration in the ratio of lipid, water, and protein [4] Of the eight reported cases [5][6][7][8][9], including three of our own, a white-matter abnormality was not detected on early scans in five; this reflects the timing of the CT scan with respect to the pathologic progression of the disease. Like- …”

Section: Resultsmentioning

confidence: 99%

Specific CT findings in Krabbe disease

Kwan

Drace

Enzmann

1984

American Journal of Roentgenology

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“…The latter is recognized as part of the general evolution of the white matter disease. 21 Post-mortem MR examination has recently been established as an appropriate tool for the investigation of MR-pathological correlations. 12 ' 22 " 24 The results in our case showing wide areas of prolonged Tl and T2 relaxation times in the white matter confirm previous MR-pathological correlations in patients with BD submitted to MR ante-mortem."…”

Section: Pathologic Studymentioning

confidence: 99%

Computed Tomography, Magnetic Resonance Imaging and Pathological Correlations in a Case of Binswanger's Disease

Mascalchi

Inzitari²,

Pozzo³

et al. 1989

Can. j. neurol. sci.

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The results of 3 computed tomography (CT) examinations carried out over a 7 year period and of a post-mortem magnetic resonance (MR) study showed aspects of a white matter disease in a hypertensive patient suffering from vascular dementia. Histopathology revealed the primary cause of dementia to be a white matter degeneration sparing the U fibers. Rarefaction of both the myelin sheaths and the axons was present together with severe thickening of the medullary arteries. These findings support the existence of Binswanger's disease (BD) as a distinct variety of arteriosclerotic dementia. CT and MR imaging are valuable aids for diagnosis. However, since there are many other causes of CT and MR demonstrated diffuse white matter degeneration in the elderly, a conclusive diagnosis of BD requires pathological confirmation. RESUME: Tomodensitometrie, imagerie par resonance magnetique nucleaire et correlations anatomopathologiques dans un cas de maladie de Binswanger Trois tomodensitometries faites sur une periode de sept ans et un examen par resonance magnetique nucleaire effectue en post-mortem ont mis en evidence des modifications compatibles avec une leuco-encephalopathie chez un patient hypertendu atteint d'une demence vasculaire. L'histopathologie a montre que la cause primaire de la demence etait une degSnerescence de la substance blanche epargnant les fibres en U. II existait une rarefaction des gaines de myeline et des axones ainsi qu'un epaississement important des arteres medullaires. Ces observations supportent la notion que la maladie de Binswanger (MB) est une variete distincte de d6mence arteriosclereuse. La tomodensitometrie et 1'imagerie par resonance magnetique nucleaire sont des aides precieuses pour le diagnostic. Cependant, comme il existe plusieurs autres causes de degenerescence de la substance blanche chez les sujets ages, qui sont evidentes a la tomodensitometrie et a l'imagerie par resonance magnetique nucleaire, une confirmation anatomopathologique du diagnostique de MB est essentielle.

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The evolution of white matter disease as seen on computed tomography.

Cited by 32 publications

References 0 publications

Paediatric White Matter Disorders: Mri and Ct Correlation

Paediatric White Matter Disorders: Mri and Ct Correlation

Specific CT findings in Krabbe disease

Computed Tomography, Magnetic Resonance Imaging and Pathological Correlations in a Case of Binswanger's Disease

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