The experience with definitive irradiation of clinically limited squamous cell cancer of the trachea

Green, Nathan; Kulber, Harvey; Landman, Michael; Pierce, Max K.

doi:10.1016/0360-3016(85)90257-3

Cited by 20 publications

(4 citation statements)

References 13 publications

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“…Radiotherapy is indicated as an adjuvant after resection, for tumors that are unresectable or medically inoperable, and for palliation of severe symptoms. [7][8][9] The usual dose of postoperative radiotherapy is 60 Gy given as 2 Gy per fraction, five fractions per week, over 6 weeks. This treatment kills residual microscopic carcinoma in the tumor bed and regional lymph nodes.…”

Section: Discussionmentioning

confidence: 99%

Adenoid Cystic Carcinoma of the Trachea Treated with PET-CT Based Intensity Modulated Radiotherapy

Haresh

Prabhakar

Rath

et al. 2008

Journal of Thoracic Oncology

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Primary tumors of the trachea are rare and are usually malignant in adults and benign in children. Adenoid cystic carcinoma, which is of salivary gland origin, account for about one thirds of adult primary tracheal tumors. A 49-year-old gentleman presented to us after undergoing a pneumonectomy elsewhere. Computed tomography scan of the thorax at our hospital showed a residual disease in the primary site, size of which was same as that in the preoperative scan. Because there was a compromised respiratory reserve due to pneumonectomy we decided to keep the radiation dose to the remaining lung as low as possible. We treated him by positron emission tomography-computed tomography (PET-CT) directed intensity modulated radiation therapy to a dose of 60 Gy in 30 Fractions over 6 weeks on a linear accelerator. PET helped in exact localization of the target on the planning CT. He tolerated the treatment very well. PET-CT done 1 year posttreatment showed no residual disease. Presently he is disease free with good pulmonary reserve.

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Section: Discussionmentioning

confidence: 99%

Adenoid Cystic Carcinoma of the Trachea Treated with PET-CT Based Intensity Modulated Radiotherapy

Haresh

Prabhakar

Rath

et al. 2008

Journal of Thoracic Oncology

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“…Radiation therapy is currently employed both for palliation of unresectable tracheal neoplasms and as an adjunct following resection of malignant neoplasms. Little encouraging information exists regarding radiation as primary therapy for tracheal neoplasms [3,5,[16][17][18]. Few conclusions can be drawn because of the small numbers of patients treated and the variations in treatment protocols utilized.…”

Section: Radiation Therapymentioning

confidence: 99%

Management of Tracheal Neoplasms

Meyers

Mathisen

1997

The Oncologist

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Primary tracheal tumors are rare neoplasms which often present with indolent and nonspecific symptoms. Despite a tendency for late presentation, more than half of patients with benign and malignant neoplasms will be candidates for curative resection upon diagnosis. This review describes the diagnostic and staging evaluation of tracheal neoplasms. Curative surgical procedures including laryngotracheal resection, tracheal resection, and carinal resection are discussed. Palliative therapies such as external beam radiation, endolumenal brachytherapy, bronchoscopic laser resection, and endoprosthetic stenting are reviewed.

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“…A radiation dose of ∼60 Gy has been most commonly reported for external beam RT, with higher doses having significant toxicity of the tracheal and esophageal tissue using historical techniques 15, 16, 17. In contrast to definitive RT, the use of definitive RT with concurrent chemotherapy for tracheal SCC has been sparingly described in the literature 2, 3, 5, 18.…”

Section: Introductionmentioning

confidence: 99%

Case report of tracheobronchial squamous cell carcinoma treated with radiation therapy and concurrent chemotherapy

Agrawal

Marcoux

Rabin

et al. 2016

Advances in Radiation Oncology

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The experience with definitive irradiation of clinically limited squamous cell cancer of the trachea

Cited by 20 publications

References 13 publications

Adenoid Cystic Carcinoma of the Trachea Treated with PET-CT Based Intensity Modulated Radiotherapy

Adenoid Cystic Carcinoma of the Trachea Treated with PET-CT Based Intensity Modulated Radiotherapy

Management of Tracheal Neoplasms

Case report of tracheobronchial squamous cell carcinoma treated with radiation therapy and concurrent chemotherapy

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