The expression of MMP-1, -8, and -13 mRNA in the periodontal ligament of rats during tooth movement with cortical punching

Gwack, Choon; Kim, Seong-Sik; Park, Soo‐Byung; Son, Woo‐Sung; Kim, Yong-Deok; Jun, Eun-Sook; Park, Mi‐Hwa

doi:10.4041/kjod.2008.38.3.187

Cited by 7 publications

(6 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In particular, there was great difference of bone density in stage 0 and stage 1 of the canine area on the opposite side of the surgical site because, even though overall bone density decreased due to transient osteopenia after orthognathic surgery, the speed of osteogenesis differed since bone metabolism is faster in the first molar near the surgical site due to RAP. In addition, similar to the research of Gwack et al 15 , remodeling of not only hard tissue muscles but also soft tissue muscles becomes faster after orthognathic surgery, and proximal segment moves forward and upward whereas distal segment moves backward and downward. As a result, stretching of muscles also caused the difference of bone healing between two areas 15,23 .…”

Section: Discussionsupporting

confidence: 51%

“…This means that bone density in panoramic radiographs decreases clinically following orthognathic surgery. Therefore, similar to the research studies of Park et al 14 and Gwack et al 15 , rapid tooth movement may result from the loss of bone density right after orthognathic surgery. This suggests the need to prevent undesirable tooth movement by controlling rapid tooth movement right after orthognathic surgery.…”

Section: Discussionmentioning

confidence: 54%

“…Through an immunohistochemical research wherein Osteoprotegerin and receptor activator of nuclear factor kappa-B (RANK) ligand-indicators of activity of osteoblast and osteoclast-were more aggressive in rats with cortical punching, Park et al 14 reported that cortical punching caused rapid tooth movement. In addition, Gwack et al 15 reported that the remodeling of connective tissues around tooth was faster in rats with cortical punching. In this study, FD decreased after orthognathic surgery, showing statistically significant difference (P<0.05); in the comparison of the canine area and the first molar area, it also decreased, and the difference was statistically significant (P <0.05).…”

Section: Discussionmentioning

confidence: 99%

“…It is also called transient osteopenia [10][11][12][13] . Park et al 14 and Gwack et al 15 conducted a immunohistochemical research and found that tooth movement is accelerated under cortical punching in the palate of rats. Note, however, that aggressive bone remodeling may have undesirable side effects due to rapid tooth movement during the treatment after surgery.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Observation of trabecular changes of the mandible after orthognathic surgery using fractal analysis

Kang

Jeong

et al. 2012

J Korean Assoc Oral Maxillofac Surg

Self Cite

View full text Add to dashboard Cite

(J Korean Assoc Oral Maxillofac Surg 2012;38:96-100) Objectives: This study sought to evaluate trabecular changes in the mandible using fractal analysis and to explain the transient osteopenia related to rapid orthodontic tooth movement after orthognathic surgery. Materials and Methods: Panoramic radiographs were taken of 26 patients who underwent bilateral sagittal split ramus osteotomy. Radiographs taken before the surgery and 1 month after surgery were overlapped, and 40×40 pixel square regions of interest were selected near the mandibular canines and 1st molars. After the image processing procedure, the fractal dimension was calculated using the box-counting method. Results: Fractal dimension after orthognathic surgery decreased in a statistically significant manner (P<0.05). The change in fractal dimension on the canine side had greater statistical significance as compared to that seen on the 1st molar side. Conclusion: This study found that bone density decreases after orthognathic surgery due to transient osteopenia related to the regional acceleratory phenomenon. This result can provide a guide to evaluating orthodontic tooth movement after orthognathic surgery.

show abstract

Section: Discussionsupporting

confidence: 51%

Section: Discussionmentioning

confidence: 54%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Observation of trabecular changes of the mandible after orthognathic surgery using fractal analysis

Kang

Jeong

et al. 2012

J Korean Assoc Oral Maxillofac Surg

Self Cite

View full text Add to dashboard Cite

show abstract

“…Another theory is that corticotomy physically decreases the mechanical resistance of tooth movement through the bone by effectively reducing cortical bone density of the side toward which the tooth is moved. 7,8,17,18 The third theory is that a complete linear-shaped decortication around a target segment can provide a focal-stress-bearing region when a heavy orthopedic force is applied. This in turn results in a medullary bone-bending effect at the decortication area rather than in the periodontal ligament space.…”

Section: Discussionmentioning

confidence: 99%

Histologic assessment of the biological effects after speedy surgical orthodontics in a beagle animal model: a preliminary study

et al. 2011

View full text Add to dashboard Cite

Objective: Speedy surgical orthodontics (SSO), an innovative orthodontic treatment, involves the application of orthopedic forces against temporary skeletal anchorage devices following perisegmental corticotomy to induce movement of specific dental segments. Herein, we report the biological effects of SSO on the teeth and periodontal structures. Methods: Five beagle dogs were divided into 2 groups and their 6 maxillary incisors were retracted en masse by applying 500 g orthopedic force against a single palatal mini-plate. Retraction was performed without and with perisegmental corticotomy in groups I and II, respectively. All animals were killed on the 70th day, and their periodontal structures were processed for histologic analyses and scanning electronic microscopy (SEM). The linear distance between the third maxillary incisor and canine was used as a benchmark to quantify the retraction amount. Results: Retraction was markedly faster and retraction amount greater in group II than in Group I. Surprisingly, Group II did not show any root resorption despite extensive retraction, while Group I showed prominent root surface irregularities. Similarly, SEM showed multiple resorption lacunae in Group I, but not in Group II. Conclusions: SSO is an effective and favorable orthodontic approach for major en masse retraction of the maxillary anterior teeth.

show abstract

Effects of low-intensity laser therapy on periodontal tissue remodeling during relapse and retention of orthodontically moved teeth

et al. 2012

View full text Add to dashboard Cite

This study was designed to investigate the effects of low-intensity laser therapy (LILT) on periodontal ligament (PDL) remodeling during relapse and retention after the completion of orthodontic movement. The maxillary central incisors (n = 104) of the 52 rats were randomly divided into five groups according to the treatment modality: baseline control group without any intervention (n = 8); relapse group without retainer after tooth movement (n = 24); retention group with fixed retainer after tooth movement (n = 24); lased relapse group without retainer after tooth movement and LILT (n = 24); lased retention group with retainer after tooth movement and LILT (n = 24). LILT was daily performed using a gallium-aluminum-arsenide diode laser in a biostimulation mode: wavelength of 780 nm, continuous waves at 70 mW output power, a preset low intensity of 1.75 W/cm(2) in contact mode, resulting in energy dose of 5 J/cm(2) per irradiation for 3 s. The animals were euthanized on days 1, 3, and 7 after removal of the orthodontic appliance. Real-time RT-PCR was performed for quantitative analysis of matrix metalloproteinases mRNA expression. Immunoreactivities of collagen and tissue inhibitor of metalloproteinase were observed on the compression and tension sides. LILT significantly facilitated the expression of five tested MMP mRNAs in both relapse and retention groups. TIMP-1 immunoreactivity was inhibited by LILT in both groups, whereas Col-I immunoreactivity was increased by LILT only in the retention group. These results indicate that LILT would act differently on the stability after orthodontic treatment according to additional retainer wearing or not. LILT when combined with a retainer on the moved teeth may shorten the retention period by accelerating periodontal remodeling in the new tooth position, whereas, LILT on the moved teeth left without any retainer would rather increase the rate of relapse after treatment.

show abstract

The expression of MMP-1, -8, and -13 mRNA in the periodontal ligament of rats during tooth movement with cortical punching

Cited by 7 publications

References 43 publications

Observation of trabecular changes of the mandible after orthognathic surgery using fractal analysis

Observation of trabecular changes of the mandible after orthognathic surgery using fractal analysis

Histologic assessment of the biological effects after speedy surgical orthodontics in a beagle animal model: a preliminary study

Effects of low-intensity laser therapy on periodontal tissue remodeling during relapse and retention of orthodontically moved teeth

Contact Info

Product

Resources

About