The extended genetic diversity of BVDV-1: Typing of BVDV isolates from France

Jacková, Anna; M, Novácková; Pelletier, Camille; Audeval, C.; Gueneau, Eric; Haffar, A.; Petit, Etienne; Rehby, Liliane; Vilček, Štefan

doi:10.1007/s11259-007-9012-z

Cited by 73 publications

(64 citation statements)

References 11 publications

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“…In contrast to this, studies conducted in mainland European countries observed a greater level of genetic diversity with their cattle populations (Jackova et al 2008;Arias et al 2003;Hornberg et al 2009;Tajima et al 2001). A possible explanation for this lower level of genetic diversity within Ireland and the UK is their geographical location (Wenzel and Nusbaum 2007).…”

Section: Resultsmentioning

confidence: 76%

“…The 5'UTR nucleotide sequence does not translation into amino acids and the N pro nucleotide sequences were not translated as nucleotide sequences provided sufficient clarity for genetic characterisation which was the aim of this study. This point is reinforced by numerous BVD genotyping studies which solely analyse nucleotide sequences (Booth et al 2013;Graham et al 2001;Vilcek et al 1999b;Jackova et al 2008;Barros et al 2006).…”

Section: The Kimura 2-parameter Is An Appropriate Model To Use In Thimentioning

confidence: 99%

“…However a minority may survive for several months. PI animals infected with a highly virulent strain of BVDV-2 may lead to the development of haemorrhagic syndrome which like, MD, has a high mortality rate within herds (Jackova et al 2008).…”

Section: Clinical Signsmentioning

confidence: 99%

“…The genomic regions most frequently used for classifying BVDV isolates are the 5'UTR, the N pro non-structural protein or the structural E2 gene (Vilcek et al 2001;Tajima et al 2001;Jackova et al 2008).…”

Section: Prevalence Of Bvdv Genotypes and Sub-genotypesmentioning

confidence: 99%

“…In many of these countries phylogenetic studies have been conducted to establish the BVDV strains affecting their cattle population (summarised in that 33 isolates where classified as BVDV-1e, 9 as BVDV-1b, 2 as BVDV-1d, 1 as BVDV-2 while three isolates were described as a new BVDV-1 subgenotype, BVDV-1l (Jackova et al 2008). A study of BVDV isolated from Spanish cattle between 1989 and 2000 identified that 21 out of 24 isolates subjected to phylogenetic analyses using the N pro gene were found to be BVDV-1b while 2 were BVDV-1c and one BVDV-1h.…”

Section: Prevalence Of Bvdv Genotypes and Sub-genotypesmentioning

confidence: 99%

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Genetic typing of bovine viral diarrhoea virus in cattle on Irish farms

O’Brien

Garvey

Walsh

et al. 2017

Research in Veterinary Science

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The genotype and subgenotype was established for 325 field viruses and one commercial vaccine viral strain based on the analysis of at least one genomic region. BVDV-1a was the prominent subgenotype (n=317) with BVDV-1b (n=6), BVDV-1d (n=1) and BVDV-1e (n=1) also observed. A number of nucleotide sequence alignments and phylogenetic trees were constructed to represent the relationship between Irish field viruses and reference strains representative of all known BVDV genotypes and subgenotypes. Evidence of both herd specific clustering and circulation of multiple strains within herds was observed; however no evidence of county specific clustering was observed. A number of completely conserved nucleotide regions were observed and the 5'UTR was found to be more conserved than the N pro fragment analysed. The results of this study provide a detailed and comprehensive insight into the genetic diversity of BVDV in circulation within Irish cattle herds and will act as a baseline reference for future BVDV genotyping studies.

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