The authors investigated the influence of the Madden-Julian oscillation (MJO) on extreme warm and cold events, which may have large social and economic impacts. The frequencies of extreme temperature events were analyzed and compared between active and inactive MJO periods by using the 7-day running average of the 850-hPa temperature during the extended boreal winter (November-April). The results show that the frequency of extreme events is significantly modulated (i.e., increased by a factor of more than 2) by the MJO with a time lag over some areas in the extratropics as well as in the tropics. In the extratropics, the modulation of the frequency of the extreme events is roughly associated with midlatitude wave responses to tropical forcing and anomalous lower-level circulation due to the MJO.The relationship between the MJO and forecast skill of extreme temperature events was also investigated by using a suite of hindcasts made with the operational one-month ensemble prediction system of the Japan Meteorological Agency. Forecast skill of extreme events occurring after active MJO periods tend to be better over some areas, compared with after inactive MJO periods. These results suggest that a realistic representation of the MJO and of the atmospheric response to the MJO in forecast models is important for providing reliable early warning information about extreme events.