The Factor Structure of the CVLT-C in Pediatric Epilepsy

Griffiths, Stephanie; Sherman, Elisabeth M. S.; Slick, Daniel J.; Lautzenhiser, Aaron; Westerveld, Michael; Zaroff, Charles M.

doi:10.1080/09297040600681315

Cited by 12 publications

(4 citation statements)

References 39 publications

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“…The WCST has been used in some models of attention to assess the shifting component of attention (Mirsky et al, 1991(Mirsky et al, , 1999, and in studies of working memory to reflect the preservation of central executive functioning in amnestic disorders (Baddeley & Wilson, 2002;Gooding et al, 2005). Finally, factor analytic studies of the CVLT have confirmed that List A Trial 1 and Trial B load together to form a factor separate from other CVLT scores (Donders, 2008;Griffiths et al, 2006;Wiegner & Donders, 1999).…”

Section: Methodsmentioning

confidence: 99%

Are working memory deficits in bipolar disorder markers for psychosis?

Allen¹,

Randall²,

Bello³

et al. 2010

Neuropsychology

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Working memory deficits have been identified in bipolar disorder, but there is evidence suggesting that these deficits may be markers for psychosis rather than affective disorder. The current study examined this issue by comparing two groups of individuals with bipolar disorder, one with psychotic features and one without psychotic features, with a group of normal controls. Working memory was conceptualized as a multicomponent system that includes auditory and visuospatial short-term stores, executive control processes, and an episodic buffer that allows for communication between short- and long-term memory stores (Baddeley & Logie, 1999). Results indicated that only executive control processes significantly differentiated the psychotic and nonpsychotic bipolar groups, although visuospatial working memory differentiated both bipolar groups from controls. The results support the idea that some aspects of working memory performance are markers for psychosis, while others may be more general markers for bipolar disorders.

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Section: Methodsmentioning

confidence: 99%

Are working memory deficits in bipolar disorder markers for psychosis?

Allen¹,

Randall²,

Bello³

et al. 2010

Neuropsychology

View full text Add to dashboard Cite

show abstract

“…After a 20-min delay, participants again recalled List A in free and cued recall manners (long-delay trials) and then had to complete a yes0no recognition test. Based on previous research investigating CVLT-C performance in pediatric clinical populations using Donders' (1999) 5-factor model (Griffiths et al, 2006;Salorio et al, 2005), and Mattson and Roebuck's (2002) analysis of CVLT-C performance in children with PAE, the following CVLT-C variables were analyzed from raw performance scores: trial 1 of List A ("attention span"), trial 5 of List A ("learning efficiency"), total trials of List A ("total learning"), short-delay free and cued recall, long-delay free and cued recall, and delayed recognition.…”

Section: Tests and Measuresmentioning

confidence: 99%

Effects of prenatal alcohol exposure on hippocampal volume, verbal learning, and verbal and spatial recall in late childhood

Willoughby

Sheard

Nash

et al. 2008

J Int Neuropsychol Soc

162

164

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Children with prenatal alcohol exposure (PAE) show deficits in verbal learning and spatial memory, as well as abnormal hippocampal development. The relationship between their memory and neuroanatomic impairments, however, has not been directly explored. Given that the hippocampus is integral for the synthesis and retrieval of learned information and is particularly vulnerable to the teratogenic effects of alcohol, we assessed whether reduced learning and recall abilities in children with fetal alcohol spectrum disorders (FASDs) are associated with abnormal hippocampal volumes. Nineteen children with FASDs and 18 typically developing controls aged 9 to 15 years were assessed for verbal learning and verbal and spatial recall and underwent structural magnetic resonance imaging. Images were analyzed for total intracranial volume and for right and left hippocampal volumes. Results revealed smaller left hippocampi and poorer verbal learning and verbal and spatial recall performance in children with FASDs than controls, as well as positive correlations between selective memory indices and hippocampal volumes only in the FASD group. Additionally, hippocampal volumes increased significantly with age in controls only, suggesting that PAE may be associated with long-term abnormalities in hippocampal development that may contribute to impaired verbal learning and verbal and spatial recall. (JINS, 2008(JINS, , 14, 1022(JINS, -1033

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“…Word lists were derived from the California Verbal Learning Test – Children’s Version (CVLT‐C, Delis et al., 1994), which has been shown to have acceptable reliability (coefficient alpha ranging from 0.72 to 0.85; Delis et al., 1994) and construct validity (Griffiths et al., 2006) in children with epilepsy. A 9‐ and 12‐word list was devised for children <9 and ≥9 years of age, respectively.…”

Section: Methodsmentioning

confidence: 99%

Accelerated long‐term forgetting in children with idiopathic generalized epilepsy

et al. 2012

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SUMMARYPurpose: The rapid forgetting of information over long (but not short) delays (accelerated long-term forgetting [ALF]) has been associated with temporal lobe epilepsy but not idiopathic generalized epilepsy (IGE). Long-term memory formation (consolidation) is thought to demand an interaction between medial temporal and neocortical networks, which could be disrupted by epilepsy/seizures themselves. The present study investigates whether ALF is present in children with IGE and whether it relates to epilepsy severity. Methods: Sixty-one children (20 with IGE and 41 healthy controls [HC]) of comparable age, sex, and parental socioeconomic status completed neuropsychological tests, including a measure of verbal learning and recall after, short (30-min) and long (7-day) delays, and recognition. Epilepsy severity was rated by treating neurologists. Key Findings: A two-way repeated measures analysis of covariance (ANCOVA) found a significant Group x Delay interaction; the children with IGE recalled (and recognized) significantly fewer words after a long, but not short (2-and 30-min) delay relative to the HC children. Moreover, greater epilepsy severity was associated with poorer recognition. Significance: This study demonstrates, to our knowledge for the first time, that children with IGE present with ALF, which is related to epilepsy severity. These findings support the notion that epilepsy/seizures themselves may disrupt long-term memory consolidation, which interferes with day-to-day functioning of children with IGE.

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The Factor Structure of the CVLT-C in Pediatric Epilepsy

Cited by 12 publications

References 39 publications

Are working memory deficits in bipolar disorder markers for psychosis?

Are working memory deficits in bipolar disorder markers for psychosis?

Effects of prenatal alcohol exposure on hippocampal volume, verbal learning, and verbal and spatial recall in late childhood

Accelerated long‐term forgetting in children with idiopathic generalized epilepsy

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