2013
DOI: 10.1515/reveh-2013-0005
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The fate and behavior of persistent, bioaccumulative, and toxic (PBT) chemicals: examining lead (Pb) as a PBT metal

Abstract: Persistent, bioaccumulative, and toxic (PBT) chemicals are a class of chemicals that resist degradation and persist in the environment for extensive periods. As a result of their persistence, when these chemicals are consumed, they bioaccumulate in the fat tissues, bones, and brain of organisms. Lead (Pb) is a PBT metal with the ability to bind irreversibly to neurons and to mimic natural minerals like calcium and zinc. The aim of this review is to examine the unique properties of a PBT, like Pb, as well as th… Show more

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Cited by 25 publications
(10 citation statements)
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“…Recently, the tendency has been towards them being more environmentally compatible. Concerning FR utilization, persistence, bioaccumulation, and toxicity (PBT), chemicals are a source of concern because they are degradation-resistant and can remain this way in the environment [ 136 ] and have been proven to be hazardous to humans and wildlife in recent years [ 137 ]. They have been known to be very effective and inexpensive for FR additives into the polymer.…”
Section: Potentialmentioning
confidence: 99%
“…Recently, the tendency has been towards them being more environmentally compatible. Concerning FR utilization, persistence, bioaccumulation, and toxicity (PBT), chemicals are a source of concern because they are degradation-resistant and can remain this way in the environment [ 136 ] and have been proven to be hazardous to humans and wildlife in recent years [ 137 ]. They have been known to be very effective and inexpensive for FR additives into the polymer.…”
Section: Potentialmentioning
confidence: 99%
“…It mimics essential minerals such as calcium and zinc, inducing chronic cardiovascular, renal, immunological and neurological diseases as well as cancer in humans and animals [1][2][3]. Pregnant women, children and city habitants are particularly at risk of Pb intoxication [4,5].…”
Section: Endoplasmic Reticulum Stress and Apoptosis Triggered By Sub-mentioning
confidence: 99%
“…Lead is one of the most widely and evenly distributed trace metals that exist in various forms in natural sources. Lead, which was deposited in the past, can still be a problem today because it neither biodegrades nor breaks down at an appreciable rate under normal environmental conditions [38]. Pb bio-accessibility is influenced by Pb contamination sources, soil properties, and particle size fractions [39].…”
Section: Status Of Lead In Soilsmentioning
confidence: 99%