The finding of antiplaque features in Acacia <i>Arabica</i> type of chewing gum

Gazi, M. I.

doi:10.1111/j.1600-051x.1991.tb01123.x

Cited by 26 publications

(23 citation statements)

References 8 publications

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“…The reduction in plaque and gingivitis scores in Group I (placebo) can be attributed to the Hawthorne effect (i.e., patients frequently appear to improve merely from the effects of being placed in a clinical trial). 17 Similar to studies by Lindhe et al 18 and Triratana et al, 19 prophylaxis and scaling were not carried out prior to the experimental phase of the present clinical study, unlike other studies by Gazi et al 20 and Brecx et al in which oral prophylaxis was carried out prior to the experimental phase. 4 Porphyromonas gingivalis and Prevotella intermedia are strongly implicated in the pathogenesis of chronic periodontitis 21 and the proteolytic activity of P. gingivalis is recognized as a potential virulence factor.…”

Section: Discussionmentioning

confidence: 40%

“…Gazi concluded that Acacia gum has the potential to inhibit early plaque formation although the long-term effect may not be there. 20 The anti-inflammatory activity of Barleria prionitis, another ingredient of gumtone gel, is proved by Singh et al 'TAF', an active fraction from the plant Barleria prionitis, exhibited significant anti-inflammatory activity against different inflammagens like carrageenan, histamine and dextran along with the inhibition of vascular permeability. 24 Another constituent of formulation is Terminalia chebula, the extract of which strongly inhibits growth, sucrose induced adherence and glucan induced aggregation of Streptococcus mutans.…”

Section: Discussionmentioning

confidence: 99%

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Short‐term clinical effects of commercially available gel containing Acacia arabica: a randomized controlled clinical trial

Pradeep¹,

Happy²,

Garg³

2010

Australian Dental Journal

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Background: Certain plants used in folk medicine serve as a source of therapeutic agent by having antimicrobial and other multi-potential effects. This prospective, randomized, placebo and positively controlled clinical trial was designed to evaluate the short-term clinical effects of a commercially available gel containing Acacia arabica in the reduction of plaque and gingival inflammation in subjects with gingivitis. Methods: Ninety subjects diagnosed with chronic generalized gingivitis were selected and randomly divided into three groups: Group I -placebo gel, Group II -gumtone gel and Group III -1% chlorhexidine gel. Clinical evaluation was undertaken using the gingival index of Loe and Silness and the plaque index at baseline, 2 weeks, 4 weeks and 6 weeks. A subjective evaluation was undertaken by questionnaire. Results: Gumtone gel showed significant clinical improvement in gingival and plaque index scores as compared to a placebo gel. This improvement was comparable to 1% chlorhexidine gel. Unlike chlorhexidine gel, gumtone gel was not associated with any discolouration of teeth or unpleasant taste. Conclusions: Gumtone gel may be a useful herbal formulation for chemical plaque control agent and improvement in plaque and gingival status.

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Section: Discussionmentioning

confidence: 40%

Section: Discussionmentioning

confidence: 99%

Short‐term clinical effects of commercially available gel containing Acacia arabica: a randomized controlled clinical trial

Pradeep¹,

Happy²,

Garg³

2010

Australian Dental Journal

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“…It is an economically valued timber tree and is used for agricultural implements and fuel wood, while the leaves are used for infodder (Anonymous 1985). The gum of A. arabica is described as a source of useful medicaments, and it is believed to be of value for treating gingivitis and for reducing plaque (Gazi 1991); the flowers of Acacia raddiana was used to attract and catch Anopheles sergentii (Müller and Schlein 2006); A. arabica was reported as insecticidal plant which can be used in insecticide preparation (Singh and Saratchandra 2005); the bioefficacies were evaluated for their oviposition inhibition, residual toxicity, and direct toxicity effects on pulse beetle, Callosobruchus maculatus (Rahman and Talukder 2006); ash was used to control the grain weevil, Sitophilus granarious (Rahman et al 2003).…”

Section: Introductionmentioning

confidence: 99%

Evaluation of indigenous plant extracts against larvae of Culex quinquefasciatus Say (Diptera: Culicidae)

Rahuman¹,

Bagavan²,

Kamaraj³

et al. 2008

Parasitol Res

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This study investigates the larvicidal potential of indigenous plant extracts from commonly used medicinal herbs as an environmentally safe measure to control the filarial vector, Culex quinquefasciatus Say (Diptera: Culicidae). The early fourth-instar larvae of C. quinquefasciatus, reared in the laboratory, were used for larvicidal assay with water, hot water, acetone, chloroform, and methanol leaf, stem-bark, and flower extracts of Acacia arabica Willd. Sans, Cedrus deodara Roxb, Hibiscus rosa-sinensis L., Mangifera indica L., Nerium indicum Mill., Nicotiana tabacum Linn., Pongamia pinnata (L.) Pierre, and Solanum nigrum Linn. All plant extracts showed moderate larvicidal effects after 24 h of exposure at 1,000 ppm; however, the highest larval mortality was found in stem-bark hot water, acetone, and methanol extracts of C. deodara (LC50 = 133.85, 141.60, and 95.19 ppm, LC90 = 583.14, 624.19, and 639.99 ppm) and leaf hot water, acetone, methanol, and chloroform extracts of N. tabacum (LC50 = 76.27, 163.81, 83.38, and 105.85 ppm, LC90 = 334.72, 627.38, 709.51, and 524.39 ppm) against the larvae of C. quinquefasciatus, respectively. This is an ideal ecofriendly approach for the control of lymphatic filariasis vector, C. quinquefasciatus.

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“…Lupeol present in the bark has an anti-inflammatory activity and tannins have antibacterial and antioxidant properties. [2526]…”

Section: Discussionmentioning

confidence: 99%

Comparative evaluation of subgingivally delivered xanthan-based chlorhexidine gel and herbal extract gel in the treatment of chronic periodontitis

Phogat

Rana

Prasad

et al. 2014

J Indian Soc Periodontol

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Background:Local drug delivery agents can effectively deliver the antimicrobial drugs in bactericidal concentration, and have shown improved clinical outcomes when used as an adjunct to mechanical therapy. The aim of this study was to evaluate the efficacy of a xanthan-based chlorhexidine gel versus herbal extracts’ gel as an adjunct to periodontal therapy in the treatment of chronic periodontitis.Materials and Methods:A total of 150 sites, age group of 30-50 years, periodontal pockets measuring 5-8 mm and diagnosed with chronic periodontitis were selected for the study. The selected sites were randomized in five groups: Scaling and root planing (SRP) alone (Group A), SRP + Chlosite gel (Group B), SRP + Herbal gel (Group C), Chlosite gel alone (Group D) and Herbal gel alone (Group E). Clinical parameters such as Plaque Index, Gingival Index, probing pocket depth and clinical attachment level were recorded at baseline and 1- and 3-month intervals.Results:After 3 months, there were statistically significant reductions in all the clinical parameters for Groups B and C compared with Group A. There was no significant reduction in all clinical parameters between Group D and E where no mechanical therapy was performed.Conclusion:The results indicate that the local application of herbal gel can be comparably used as chlorhexidine gel in the treatment of chronic periodontitis as an adjunct to mechanical periodontal therapy.

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The finding of antiplaque features in Acacia Arabica type of chewing gum

Cited by 26 publications

References 8 publications

Short‐term clinical effects of commercially available gel containing Acacia arabica: a randomized controlled clinical trial

Short‐term clinical effects of commercially available gel containing Acacia arabica: a randomized controlled clinical trial

Evaluation of indigenous plant extracts against larvae of Culex quinquefasciatus Say (Diptera: Culicidae)

Comparative evaluation of subgingivally delivered xanthan-based chlorhexidine gel and herbal extract gel in the treatment of chronic periodontitis

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