The first example ot the benzo[b]pyrimido[4,5‐f]azocine king system

Abstract

Base catalyzed cyclization of ethyl 4‐[2‐(2‐amino‐4,5‐dimethoxyphenyl)ethyl]‐2‐phenylpyrimidine‐5‐carboxylate, derived from ethyl 4‐methyl‐2‐phenyl‐5‐pyrimidinecarboxylate and 3,4‐dimethoxy‐6‐nitrobenz‐aldehyde, gave 5,6‐dihydro‐8,9‐dimethoxy‐3‐phenylbenzo[b]pyrimido[4,5‐f]azocine‐12(11H)‐one, the first reported example of this ring system.