The first synthesis of peracetyl glycosyl aurone derivatives and aurone glucosides

Kafle, Arjun; Bhattarai, Shrijana; Handy, Scott T.

doi:10.1016/j.tet.2020.131528

Cited by 5 publications

(1 citation statement)

References 34 publications

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“…It can also be obtained from chemical synthesis. Kafle et al 34 in their research claim to be the first research group to carry out the total synthesis of aurone glycosides. The compound was tested on 4T1 breast cancer cells and reported to be very active with an IC50 value of 2.34 μM and has a mechanism of inhibiting cyclin D1 and cyclin E.…”

Section: In Vitro Cytotoxicity Assaymentioning

confidence: 99%

Antibacterial, Antioxidant, and Cytotoxic Flavonoid Compound from Sterculia Quadrifida Leaves

2021

TJNPR

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The genus Sterculia generally grows in the tropics and sub-tropics. 1 the genus had many secondary metabolites such as alkaloids, saponins, triterpenoids, tannins, and phenolics. 2 Several species in this genus are traditionally used to treat ulcers, diarrhoea, fever, stroke, diabetes, and inflammation. 3 Sterculia quadrifida, a plant called "Faloak" in Indonesia, has a significant role in folk medicine, especially for infectious diseases, as anti-hepatitis, and anticancer. 4 However, studies of S. quadrifida plants are still limited. Only a few studies have been conducted in the last decade investigating the phytochemical content of S. quadrifida plants and isolating triterpenoids and anthraquinone compounds. 5,6 Some of these compounds show pharmacological effects, such as anti-hepatitis 7 , immunostimulant, antioxidant, anti-cancer, and antibacterial activities. 7-9 Among all compounds, flavonoids have the potential to be used as anti-infective, antioxidant, and anti-cancer agent. 10 Therefore, this study aimed to isolate the active antibacterial, antioxidant, and anti-cancer compounds from the methanol leaves extract of S. quadrifida using chromatographic techniques.

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Section: In Vitro Cytotoxicity Assaymentioning

confidence: 99%

Antibacterial, Antioxidant, and Cytotoxic Flavonoid Compound from Sterculia Quadrifida Leaves

2021

TJNPR

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Hemiindigoids as Prominent Photoswitch Scaffolds

Gernet,

Toursel,

Balivet

et al. 2024

ChemPhotoChem

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Hemiindigo photoswitches, a class of chromophores derived from the well‐known indigo dye, have attracted considerable interest over the past two decades. These compounds are unique in their ability to absorb light in the visible region of the spectrum in both isomeric states, making them ideal for applications where high‐energy UV light is not tolerated. A particularly attractive feature of hemiindigoids is that, despite their rigid structures, they undergo significant and controllable changes during the photoisomerisation process. Moreover, they exhibit a combination of high thermal bistability, pronounced photochromism, and fast, efficient photoisomerisation, positioning hemiindigoid photoswitches as versatile chromophores. This review summarises the current developments and advances in hemiindigoid photoswitches, including their synthesis, photoswitching performance, and applications, with a strong focus on their practical use as reversible triggers in fields ranging from photopharmacology to advanced materials.

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What about the progress in the synthesis of flavonoid from 2020?

Liu

2022

European Journal of Medicinal Chemistry

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The first synthesis of peracetyl glycosyl aurone derivatives and aurone glucosides

Cited by 5 publications

References 34 publications

Antibacterial, Antioxidant, and Cytotoxic Flavonoid Compound from Sterculia Quadrifida Leaves

Antibacterial, Antioxidant, and Cytotoxic Flavonoid Compound from Sterculia Quadrifida Leaves

Hemiindigoids as Prominent Photoswitch Scaffolds

What about the progress in the synthesis of flavonoid from 2020?

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