The flavonoid chemosystematics of two Teucrium species from Southern Sinai, Egypt

Teucrium polium plant extract inhibits cell invasion and motility of human prostate cancer cells via the restoration of the E-cadherin/catenin complex

“…However, this plant extract has been traditionally used for centuries in the treatment of several diseases and inflammations (Said et al, 2002;Abu-Irmaileh and Afifi, 2003) and it has also been reported to have antioxidant properties (Suboh et al, 2004). The bioactive compounds contained flavonoids and neo-clerodane diterpenoids (Kawashty et al, 1999;Bruno et al, 2003). Nevertheless, in our investigation we found that this plant (used alone) has an important effect on cell proliferation and cell cycle deregulation of human prostate cancer cells as well as other human cancer cells such as breast, lung and cervical (unpublished data).…”

Phytochemistry and Medicinal Properties of Teucrium polium L. (Lamiaceae)

“…Flavonoids are polyphenols that are found universally in dietary and medicinal plants with a wide variety of biological activities (Rizk et al , ). Several authors have also reported on the presence of various flavonoids such as apigenin, luteolin, rutin, cirsiliol, cirsimaritin, salvigenin and eupatorin in the roots, aerial parts and inflorescences of the plant (Table ) (Carreiras et al , ; Hachicha et al , ; Harborne et al , ; Kawashty et al , ; Litvinenko et al , ; Sharififar et al , ; Rizk et al , ; Verykokidou‐Vitsaropoulou and Vajias, ).…”

“…Plants belonging to Teucrium genus have been shown to contain different classes of compounds such as neoclerodane diterpenoids (Piozzi, 1981(Piozzi, , 1994Piozzi et al, 1987Piozzi et al, , 1998, the chemotaxonomic markers of the genus (Piozzi et al, 2005), monoterpenes (Bruno et al, 2002), sesquiterpenes (Bruno et al, 1993), polyphenols, flavonoids (Kawashty et al, 1999;Rizk et al, 1986) and fatty acid esters (Boulila et al, 2008;Hachicha et al, 2009). Up to now, more than 134 active substances with wide structural and chemical diversities have been isolated and characterized from the aerial parts, roots and seeds of T. polium subspecies.…”

Effects of aqueous extracts of medicinal plants on MNNG-treated rat hepatocytes in primary cultures

“…• Teucrium polium L. (Labiatae) is traditionally used for the treatment of kidney and liver diseases and inflammations (Said et al, 2002;Abu-Irmaileh and Afifi, 2003) and has also been reported to have antioxidant properties (Suboh et al, 2004). The bioactive compounds contained are flavonoids (Kawashty et al, 1999) and neo-clerodane diterpenoids (Bruno et al, 2003). • Trigonella foenum-graecum L. (Fabaceae) is used traditionally for the treatment of diabetes (Said et al, 2002), ulcers, inflammations andpoisonings (Abu-Irmaileh andAfifi, 2003).…”