The interaction of supernova shocks and interstellar clouds is an important astrophysical phenomenon since it can result in stellar and planetary formation. Our experiments attempt to simulate this mass-loading as it occurs when a shock passes through interstellar clouds. We drive a strong shock using the Omega laser ( 5 kJ) into a foam-…lled cylinder with an embedded Al sphere (diameter D = 120 m) simulating an interstellar cloud. The density ratio between Al and foam is 9. We have previously reported on the interaction between shock and cloud, the ensuing Kelvin-Helmholtz and Widnall instabilities, and the rapid stripping of all mass from the cloud.We now present a theory that explains the rapid mass-stripping. The theory combines (1) the integral momentum equations for a viscous boundary layer, (2) the equations for a potential ‡ow past a sphere, (3) Spalding's law of the wall for turbulent boundary layers, and (4) the skin friction coe¢ cient for a turbulent boundary layer on a ‡at plate. The theory gives as its …nal result the mass stripped from a sphere in a turbulent high Reynolds number ‡ow, and it agrees very well with our experimental observations.