The Fluorescence of Lignum nephriticum: A Flash Back to the Past and a Simple Demonstration of Natural Substance Fluorescence

Muyskens, Mark A.; Vitz, Ed

doi:10.1021/ed083p765

Cited by 29 publications

(19 citation statements)

References 10 publications

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“…Fluorescence is a technique that relies on the absorption of excitation light by an object (usually fluorophores) followed by a subsequent emission of light at a higher wavelength than that of the excitation light [227,228]. Fluorophores are microscopic molecules (chemical compounds, synthetic polymers, proteins, etc.)…”

Section: Fluorescence-based Single-molecule Studiesmentioning

confidence: 99%

A Critical Review on the Sensing, Control, and Manipulation of Single Molecules on Optofluidic Devices

Rahman

Islam

et al. 2022

Micromachines

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Single-molecule techniques have shifted the paradigm of biological measurements from ensemble measurements to probing individual molecules and propelled a rapid revolution in related fields. Compared to ensemble measurements of biomolecules, single-molecule techniques provide a breadth of information with a high spatial and temporal resolution at the molecular level. Usually, optical and electrical methods are two commonly employed methods for probing single molecules, and some platforms even offer the integration of these two methods such as optofluidics. The recent spark in technological advancement and the tremendous leap in fabrication techniques, microfluidics, and integrated optofluidics are paving the way toward low cost, chip-scale, portable, and point-of-care diagnostic and single-molecule analysis tools. This review provides the fundamentals and overview of commonly employed single-molecule methods including optical methods, electrical methods, force-based methods, combinatorial integrated methods, etc. In most single-molecule experiments, the ability to manipulate and exercise precise control over individual molecules plays a vital role, which sometimes defines the capabilities and limits of the operation. This review discusses different manipulation techniques including sorting and trapping individual particles. An insight into the control of single molecules is provided that mainly discusses the recent development of electrical control over single molecules. Overall, this review is designed to provide the fundamentals and recent advancements in different single-molecule techniques and their applications, with a special focus on the detection, manipulation, and control of single molecules on chip-scale devices.

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Section: Fluorescence-based Single-molecule Studiesmentioning

confidence: 99%

A Critical Review on the Sensing, Control, and Manipulation of Single Molecules on Optofluidic Devices

Rahman

Islam

et al. 2022

Micromachines

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“…Furthermore, in the Florentine Codex, Fray Bernardino de Sahagún refers to the use of “Coatli” for fever or retention of urine [ 7 ]. In the following centuries (XVI and XVII), it was taken to Europe where it was known as Lignum nephriticum [ 8 , 9 ]. Later, it continued to be consumed in a traditional way by Mexicans for the control of urinary, contraceptive [ 10 ], antidiarrheal, and antiseptic disorders, as well as for the control of diabetes [ 11 , 12 ].…”

Section: Introductionmentioning

confidence: 99%

Phytochemical and Pharmacological Study of the Eysenhardtia Genus

Campoy

Garcia

Muñiz-Ramírez

2020

Plants

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The participation of natural products in health care has been remarkable, and today they continue to play a key role in the discovery and development of new treatments. Phytochemical studies together with pharmacological tests have managed to integrate bioactive agents as an alternative solution to reduce or regulate the problems caused by diseases. The Eysenhardtia genus is a family of plants that are rich in secondary metabolites, which have shown potential activity in the control and mitigation of urinary disorders, diabetes, oxidative stress, protein glycosylation, microbial infections, inflammation, pain or discomfort, muscle contractions, cytotoxicity, or as a cellular or neuronal signaling modulator. These conditions generally appear in comorbid diseases, which motivated the bibliographic review associated with the plant. This document presents the beneficial actions produced by Eysenhardtia extracts and/or bioactives to inhibit, control, or reduce the complications or discomfort of degenerative diseases and thus generate new therapeutic alternatives.

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“…It was derived from the wood of two components, Pterocarpusindicus and Eysenhardtiapolystachya. [1][2][3][4] The chemical component responsible for the fluorescence is matlaline, that is the oxidation product for one of the flavonoids component in this wood. [5] In 1819, Edward D. Clarke [6] and in 1822 René Just Haüy [7] described fluorescence in fluorites, David Brewster explained the phenomenon for chlorophyll in 1833 [8] and John Herschel did the same for quinine in 1845 [9] .…”

Section: Introductionmentioning

confidence: 99%