The form of the volume pulse in the finger pad in health, arteriosclerosis, and hypertension

Dillon, John; Hertzman, Alrick B.

doi:10.1016/s0002-8703(41)90966-3

Cited by 66 publications

(28 citation statements)

References 10 publications

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“…Aortic stiffness increases with age (5)(6)(7)(8) and cardiovascular risk factors (9). An index of large artery stiffness (SI DVP ) derived from the digital volume pulse (DVP) measured by photoplethysmography was well correlated with PWV and age (10)(11)(12)(13). Photoplethysmography can measure DVP easily by using transmission of infrared light through the finger pad (11,14).…”

Section: Introductionmentioning

confidence: 99%

Stiffness index derived from digital volume pulse as a marker of target organ damage in untreated hypertension

Chen¹,

Tsai²,

Lin

et al. 2005

Blood Pressure

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Section: Introductionmentioning

confidence: 99%

Stiffness index derived from digital volume pulse as a marker of target organ damage in untreated hypertension

Chen¹,

Tsai²,

Lin

et al. 2005

Blood Pressure

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“…[1][2][3] The pioneering work of Takazawa et al 4 has shown that the DVP resembles the carotid pressure wave and varies, as does the carotid pressure wave, with vasodilator and vasoconstrictor drugs. Analysis of this pulse waveform has been used to characterize the effects of aging and of vasodilator drugs on the circulation.…”

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confidence: 99%

Noninvasive Assessment of the Digital Volume Pulse

et al. 2000

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Abstract-The digital volume pulse can be recorded simply and noninvasively by photoplethysmography. The objective of the present study was to determine whether a generalized transfer function can be used to relate the digital volume pulse to the peripheral pressure pulse and, hence, to determine whether both volume and pressure pulse waveforms are influenced by the same mechanism. The digital volume pulse was recorded by photoplethysmography in 60 subjects (10 women, aged 24 to 80 years), including 20 subjects with previously diagnosed hypertension. Simultaneous recordings of the peripheral radial pulse and digital artery pulse were obtained by applanation tonometry and a servocontrolled pressure cuff (Finapres), respectively. In 20 normotensive subjects, measurements were obtained after the administration of nitroglycerin (NTG, 500 g sublingually). Transfer functions obtained by Fourier analysis of the waveforms were similar in normotensive and hypertensive subjects. In normotensive subjects, transfer functions were similar before and after NTG. By use of a single generalized transfer function for all subjects, the radial and digital artery pressure waveforms could be predicted from the volume pulse with an average root mean square error of 4.4Ϯ2.0 and 4.3Ϯ1.9 mm Hg (meanϮSD) for radial and digital artery waveforms, respectively, similar to the error between the 2 pressure waveforms (4.4Ϯ1.4 mm Hg). The peripheral pressure pulse is related to the digital volume pulse by a transfer function, which is not influenced by effects of hypertension or NTG. Effects of NTG on the volume pulse and pressure pulse are likely to be determined by a similar mechanism. (Hypertension. 2000;36:952-956.)Key Words: plethysmography Ⅲ hypertension, essential Ⅲ pulse Ⅲ nitroglycerin Ⅲ tonometry A digital volume pulse (DVP) can be obtained by measuring infrared light transmission through the finger (photoplethysmography). 1-3 The pioneering work of Takazawa et al 4 has shown that the DVP resembles the carotid pressure wave and varies, as does the carotid pressure wave, with vasodilator and vasoconstrictor drugs. Analysis of this pulse waveform has been used to characterize the effects of aging and of vasodilator drugs on the circulation. 4 However, the physical characteristics that determine the volume pulse waveform are not fully understood. By contrast, the peripheral pressure pulse derived from the radial or digital artery has been subject to much analysis by O'Rourke and colleagues, 5-7 who have established that the peripheral pressure pulse is influenced by pressure wave reflection mainly from the lower body and by pressure wave velocity. Transmission along the upper limb also influences the radial or digital artery pressure pulse (P rad and P dig , respectively), but this influence remains approximately constant across subjects and during the administration of systemically acting vasodilator drugs. 8 Thus, changes in the peripheral pressure pulse are determined mainly by changes in pressure wave reflection within the trunk and lo...

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“…In this issue of Clinical Science, Millasseau et al [12], in a series of elegant studies, describe the use of pulse contour analysis to derive quantitative data concerning large arterial stiffness in the hope of providing new insights into ventricular vascular interaction. Using the established technique of photoplethysmography [13,14], they have devised a reproducible parameter termed ' stiffness index ' by measuring the time delay between direct and reflected waves in the digital volume pulse [12]. Since this measure will be determined, to a large extent, by velocity of the arterial waveform in the aorta and large arteries, it is perhaps unsurprising that they were able to demonstrate a significant correlation between the stiffness index and carotid-femoral pulse wave velocity (PWV).…”

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confidence: 99%