2007
DOI: 10.1016/j.mehy.2006.06.035
|View full text |Cite
|
Sign up to set email alerts
|

The function of proprioceptors in bone organization: A possible explanation for neurogenic heterotopic ossification in patients with neurological damage

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1

Citation Types

0
10
0
2

Year Published

2008
2008
2021
2021

Publication Types

Select...
5
2
1

Relationship

0
8

Authors

Journals

citations
Cited by 29 publications
(12 citation statements)
references
References 20 publications
0
10
0
2
Order By: Relevance
“…Humoral factors; neural factors; local factors, including hypoxia and hypercalcemia; changes in the sympathetic nervous system activity; long-term immobilization; and mobilization process with frequent exercise periods after the long-term immobilization have been attributed to cause some syndromes with neurogenic ectopic bone formation and calcification, including Pellegrini-Stieda syndrome (PSS) (2). PSS is characterized by the calcification and ossification of the medial collateral ligament (MCL), usually associated with a history of direct or indirect trauma and repetitive microtrauma (3)(4)(5)(6).…”
Section: Introductionmentioning
confidence: 99%
“…Humoral factors; neural factors; local factors, including hypoxia and hypercalcemia; changes in the sympathetic nervous system activity; long-term immobilization; and mobilization process with frequent exercise periods after the long-term immobilization have been attributed to cause some syndromes with neurogenic ectopic bone formation and calcification, including Pellegrini-Stieda syndrome (PSS) (2). PSS is characterized by the calcification and ossification of the medial collateral ligament (MCL), usually associated with a history of direct or indirect trauma and repetitive microtrauma (3)(4)(5)(6).…”
Section: Introductionmentioning
confidence: 99%
“…Consequently, the tissues become more vulnerable to trauma. When there is an interruption in the neuronal network based on the data from the receptors placed in the ligaments and muscles, ectopic bone formation can occur (16).…”
mentioning
confidence: 99%
“…Passive forced exercises create a trauma effect because of misunderstanding of proprioceptive receptors. Hence, it is accepted that HO is also associated with the proprioceptive defect in patients with TBI (16). This situation can be explained by the fact that the proteins inducing bone growth are not under control anymore.…”
mentioning
confidence: 99%
“…Neurogenic heterotopic ossification is reported to occur in 25% to 60% of adult patients with spinal cord injury [6][7][8][9], and in 10% of paediatric patients [10].…”
Section: Epidemiologymentioning
confidence: 99%
“…Capmos de Paz et al have reported that in CNS injury the mechanism of HO could be due to dysfunction of proprioception, so MSCs would underwent osteogenic differentiation on ligaments and muscle as an answer to stimuli [6].…”
Section: Mechanism and Pathological Changes In Nho Following Scimentioning
confidence: 99%