The functionalization of gold nanoparticles as a novel platform for the highly efficient electrochemical detection of silver ions

Zhang, Xiao; Han, Meng; Qin, Xin; Sang, Xueqing; Zhang, Yun; Yuan, Yali

doi:10.1039/d0an01870h

Cited by 18 publications

(6 citation statements)

References 45 publications

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“…Hg 2+ can combine with two thymine bases (T) and mediate T–T mismatch to form a stable T–Hg 2+ –T structure which is more durable than the natural adenine–thymine (A–T) base pair with a binding constant close to 10 6 M −1 [ 74 ]. Ag + can selectively interact with cytosine (C)-rich oligonucleotide strands to form C–Ag + –C mismatch [ 75 ]. These impressive mismatches belong to coordination bonds, and on these principles, significant efforts have been made for high selectivity and sensitivity to determine Hg 2+ [ 40 , 76 ] and Ag + [ 77 , 78 ].…”

Section: Biorecognition Elementsmentioning

confidence: 99%

Recent Advancements in Electrochemical Biosensors for Monitoring the Water Quality

et al. 2022

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The release of chemicals and microorganisms from various sources, such as industry, agriculture, animal farming, wastewater treatment plants, and flooding, into water systems have caused water pollution in several parts of our world, endangering aquatic ecosystems and individual health. World Health Organization (WHO) has introduced strict standards for the maximum concentration limits for nutrients and chemicals in drinking water, surface water, and groundwater. It is crucial to have rapid, sensitive, and reliable analytical detection systems to monitor the pollution level regularly and meet the standard limit. Electrochemical biosensors are advantageous analytical devices or tools that convert a bio-signal by biorecognition elements into a significant electrical response. Thanks to the micro/nano fabrication techniques, electrochemical biosensors for sensitive, continuous, and real-time detection have attracted increasing attention among researchers and users worldwide. These devices take advantage of easy operation, portability, and rapid response. They can also be miniaturized, have a long-life span and a quick response time, and possess high sensitivity and selectivity and can be considered as portable biosensing assays. They are of special importance due to their great advantages such as affordability, simplicity, portability, and ability to detect at on-site. This review paper is concerned with the basic concepts of electrochemical biosensors and their applications in various water quality monitoring, such as inorganic chemicals, nutrients, microorganisms’ pollution, and organic pollutants, especially for developing real-time/online detection systems. The basic concepts of electrochemical biosensors, different surface modification techniques, bio-recognition elements (BRE), detection methods, and specific real-time water quality monitoring applications are reviewed thoroughly in this article.

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Section: Biorecognition Elementsmentioning

confidence: 99%

Recent Advancements in Electrochemical Biosensors for Monitoring the Water Quality

et al. 2022

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“…Additionally, the maximum permissible concentration of Ag + in drinking water is specified as 0.93 µM and 0.36 µM, respectively. Furthermore, WHO limited the threshold for exposure of silver in water for fish and microorganisms to lower than 1.6 nmol L −1 [27,28]. Consequently, the detection of trace amounts of Ag + is crucial for environmental protection and public health [29][30][31][32][33].…”

Section: Introductionmentioning

confidence: 99%

Cytosine-Rich Oligonucleotide and Electrochemically Reduced Graphene Oxide Nanocomposite for Ultrasensitive Electrochemical Ag+ Sensing

Abbas,

Jang,

Kim

2024

Nanomaterials

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Silver ions (Ag+) are crucial in various fields, but pose environmental and health risks at high concentrations. This study presents a straightforward approach for the ultra-trace detection of Ag+, utilizing a composite of a cytosine-rich oligonucleotide (CRO) and an electrochemically reduced graphene oxide (ERGO). Initially, ERGO was synthesized on a glassy carbon electrode (GCE) through the reduction of graphene oxide (GO) via cyclic voltammetry. A methylene blue-tagged CRO (MB-CRO) was then anchored to the ERGO surface through π–π interactions, resulting in the formation of an MB-CRO-modified ERGO electrode (MB-CRO/ERGO-GCE). The interaction with Ag+ ions induced the formation of silver-mediated C-Ag+-C coordination, prompting the MB-CRO to adopt a hairpin structure. This conformational change led to the desorption of the MB-CRO from the ERGO-GCE, causing a variation in the redox current of the methylene blue associated with the MB-CRO. Electrochemical assays revealed that the sensor exhibits extraordinary sensitivity to Ag+ ions, with a linear detection range from 1 femtomolar (fM) to 100 nanomolars (nM) and a detection limit of 0.83 fM. Moreover, the sensor demonstrated high selectivity for Ag+ ions and several other benefits, including stability, reproducibility, and straightforward fabrication and operational procedures. Additionally, real sample analyses were performed using the modified electrode to detect Ag+ in tap and pond water samples, yielding satisfactory recovery rates.

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“…Noble gold nanoparticles (AuNPs) have gained tremendous potential both in academia and industry for various applications, including catalysis, sensing, photonics, analytics, surface-enhanced Raman scattering, photochemistry, optoelectronics, energy conversion, and biomedicine, as contrast agents in X-ray computed/photoacoustic topography, , and in vaccine development . Benefiting from their unique morphology-dependent optical and electronic properties due to localized surface plasmon resonance, vibrant AuNP chromophores could be designed .…”

Section: Introductionmentioning

confidence: 99%

Sustainable Exscalar Monodispersed Gold Nanoparticles with Enhanced Dispersion Stability and Biocompatibility for Theragnostics

Bhatt,

Rajavel,

Parimi

et al. 2023

ACS Appl. Nano Mater.

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The stability and dispersity of gold nanoparticles (AuNPs) against various biological, physicochemical, and physiological transformations while retaining biocompatibility are fundamental for their myriad utilization in various theragnostic applications. Besides, it would be highly imperative if the AuNPs could be generated using environmentally sustainable procedures. Remarkably stable, monodispersed AuNPs with robustness against centrifugation, freeze-thawing, lyophilization, acids, bases, electrolytes, and polar solvents are generated by utilizing fish scale wastes. The AuNPs inherited self-integrity and dispersity across various clinically significant biological fluids including phosphate buffer saline, growth mediums, human blood serum, saliva, and urine. Human blood serum interactions revealed negligible protein corona consortium and biocompatibility with no hemolysis or cytotoxicity toward peripheral blood mononuclear cells. Astonishingly, endurance to all these biological, physicochemical, and physiological discrepancies was comparable to that of universal stabilizer thiolated polyethylene glycol (PEG) sorbed AuNPs. Such high stability and wide dispersity are attributed to the firm shielding of AuNPs by the oligopeptide fragments excreted from the scales, which also endowed AuNP functionalization to diverse drugs. Notably, our results develop a biogenic production of monodispersed AuNPs with natural sturdiness against harsh laboratory and clinical environments to substitute the plunged biocompatibility of PEG-Au sulfur chemisorption and PEG-Au physisorption approaches for various imaging and drug delivery applications.

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The functionalization of gold nanoparticles as a novel platform for the highly efficient electrochemical detection of silver ions

Abstract: Herein a novel electrochemical biosensor was constructed for highly efficient detection of silver ion. A porous platform constructed by functionalized gold nanoparticles (AuPP) was electropolymerized on the gold electrode surface....

Cited by 18 publications

References 45 publications

Recent Advancements in Electrochemical Biosensors for Monitoring the Water Quality

Recent Advancements in Electrochemical Biosensors for Monitoring the Water Quality

Cytosine-Rich Oligonucleotide and Electrochemically Reduced Graphene Oxide Nanocomposite for Ultrasensitive Electrochemical Ag+ Sensing

Sustainable Exscalar Monodispersed Gold Nanoparticles with Enhanced Dispersion Stability and Biocompatibility for Theragnostics

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