The gastroprotective effect of oxycellulose pellets on gastric ulcers

Gajdziok, Jan; Bautzova, Tereza; Rabišková, Miloslava; Pellequer, Yann; Lamprecht, Alf

doi:10.1007/s10570-013-9894-6

Cited by 1 publication

(2 citation statements)

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“…In the production of solid drug forms, the OC can be used to make coatings for the film-coated tablets in combination with other polymers, since the OC is very fragile and not suitable for this application as such (Bajerová et al, 2009). Gajdziok et al (2013) have determined that the OC in the form of Na-salt (NaOC) is better as an excipient in tablets than the acidic form of the OC. Thus, NaOC in combination with hydroxypropyl-methyl cellulose as a hydrophiliclipophilic matrix enables the gradual release of caffeine from the tablets that can be used in professions requiring increased alertness, such as drivers, pilots etc.…”

Section: Auxiliary Materials In Pharmaceutical Technology and Drug Ca...mentioning

confidence: 99%

“…The gels with the OC in the form of Na-salts proved to be excellent enterosorbents with antiulcer and detoxifying effects (Gert et al, 2005). The gastroprotective activity was improved by combining the OC in the form of oral tablets with glycyrrhizin, triterpene glycosides from licorice (Gajdziok et al, 2013), while the OC in the form of beads with controlled drug release was used as a carrier for ranitidine .…”

Section: Auxiliary Materials In Pharmaceutical Technology and Drug Ca...mentioning

confidence: 99%

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Medical and pharmaceutical application of oxidized cellulose

Grabovac

Sailović

Lipic

2020

GHTERS

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Cellulose is the most abundant natural polymer and versatile starting material for chemical modification for obtaining products with various applications. The oxidation of cellulose results in derivatives with improved properties, including the products with new, specific features that can be used for medical and pharmaceutical purposes. Due to its biocompatibility and biodegradibility, the oxidized cellulose (6-carboxycellulose) is widely used as a hemostatic agent, as a barrier for the prevention of postsurgical adhesion, in bandage products for covering different wounds, as an excipient in the production of tablets, various gels and pharmaceutical suspensions. In addition to these applications, the oxidized cellulose may be used for the production of surgical sutures, as a drug carrier in products with gradual/controlled release, and as a material in tissue engineering.

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Section: Auxiliary Materials In Pharmaceutical Technology and Drug Ca...mentioning

confidence: 99%

Section: Auxiliary Materials In Pharmaceutical Technology and Drug Ca...mentioning

confidence: 99%