The Gene-Diet Attica Investigation on childhood obesity (GENDAI): overview of the study design

Papoutsakis, Constantina; Vidra, Nikoleta V.; Hatzopoulou, Ioanna; Tzirkalli, Maria; Farmaki, Anastasia-Eleni; Evagelidaki, Evagelia; Kapravelou, Garyfallia; Κοντελέ, Ιωάννα; Skenderi, Katerina; Yannakoulia, Mary; Dedoussis, George

doi:10.1515/cclm.2007.080

Cited by 22 publications

(20 citation statements)

References 33 publications

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“…53,54 Since this increased energy intake is usually concomitant to a reduced physical activity level, Greek normal-weight children are found to exhibit less sedentary activities. 55 Likewise, Greek girls participating in more than 3 hours of extracurricular sport activities are 59% less likely to be OW/ OB than their non-participating counterparts.…”

Section: Sensitivity Analysesmentioning

confidence: 99%

Ten-Year obesity and overweight prevalence in Greek children: A systematic review and meta-analysis of 2001-2010 data

Kotanidou¹,

Grammatikopoulou²,

Spiliotis³

et al. 2013

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ObJEctIVE: While the Us today has the highest rates worldwide of obesity, Europe, and particularly southern Europe, is catching up fast. the aim of this study was to report the prevalence of obesity in Greek children, aged 1-12 years. DEsIGN: A systematic review-including all studies published in English and Greek from January 2001 until December 2010 regarding childhood obesity, using the IOtF criteria-was performed. twenty-five out of 134 published studies were finally selected, including 219,996 boys and 210,772 girls. rEsULts: Meta-analysis revealed that 10.2% (cI 95%: 9.8-10.7%) of Greek children (1-12 years) are obese, 23.7% (cI 95%: 22.7-24.8%) are overweight and the combined prevalence of overweight and obesity is 34% (cI 95%: 32.7-35.3%). subgroup analysis by gender showed that 11% of the boys and 9.7% of the girls were obese, while 24.1% of the boys and 23.2% of the girls were overweight. the combined prevalence of excess in body weight predominated in boys (35%), while in girls the above prevalence was 32.7%. cumulative analysis revealed an upward trend of the phenomenon (

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Section: Sensitivity Analysesmentioning

confidence: 99%

Ten-Year obesity and overweight prevalence in Greek children: A systematic review and meta-analysis of 2001-2010 data

Kotanidou¹,

Grammatikopoulou²,

Spiliotis³

et al. 2013

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“…24 Briefly, normal-weight children were recruited from fifth and sixth grade classes of several elementary schools in the region of Attica, Greece. The selected schools (40 schools in a total of 593 in the region) were all in socioeconomically similar urban ureas.…”

Section: Normal-weight Subjects (Controls)mentioning

confidence: 99%

The combined effect of MC4R and FTO risk alleles on childhood obesity in Greece

Lazopoulou¹,

Gkioka²,

Ντάλλα³

et al. 2014

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2015, 14(1):126-133 Address for correspondence: Christina Kanaka-Gantenbein, MD, PhD, Associate Professor for Paediatrics Endocrinology-Juvenile Diabetes, First Department of Paediatrics, University of Athens Medical School, "Agia Sophia" Children's Hospital, Thivon & Livadias Str., GR 11527, Goudi, Athens, Greece, E-mail: chriskan@med.uoa.gr Received: 02-03-201402-03- , Accepted: 18-06-2014 Research paper epidemic. It has been estimated that in 2010, 43 million children aged <5 years were overweight or obese and that by 2020 this percentage will have risen to 60 million children.1 Contrary to prior common beliefs, it has been proved that "heavy" children will grow into unhealthy, obese adults with a plethora of medical conditions, this rendering the current epidemic a global health crisis on multiple levels. Greece has the highest percentage of overweight and obese adolescents in Europe, at 44% and 11%, respectively.

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“…The Gene and Diet Attica Investigation (GENDAI) target population was children attending the fifth and sixth grades living in the Attica region of Greece, as described previously (15). The GENDAI cohort is comprised of 1138 adolescent children (53% girls; mean age: 11.2"0.7 years) randomly selected from elementary schools in Attica.…”

Section: Subjectsmentioning

confidence: 99%

Peroxisome proliferator-activated receptor-γ (PPARγ) Pro12Ala polymorphism and risk for pediatric obesity

Dedoussis

Vidra

Butler

et al. 2009

Clinical Chemistry and Laboratory Medicine

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Background: Variation in the peroxisome-proliferatoractivated receptor g (PPARg) gene has been reported to alter the risk for adiposity in adults. Methods: We investigated the gender related association between the Pro12Ala variant (rs1801282) in obesity and insulin resistance traits in 794 peri-adolescent children aged 10-12 years of Greek origin from the Gene and Diet Attica Investigation (GENDAI) cohort. Results: Gender stratified analysis suggested that in peri-adolescent boys, Ala carriers exhibited lower measures of skinfold (triceps: 16.9"6.9 vs. 19.4"7.9 mm, ps0.014; subscapular: 9.6"4.5 vs. 11.2"5.4 mm, ps0.016) and lower adiponectin concentrations

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The Gene-Diet Attica Investigation on childhood obesity (GENDAI): overview of the study design

Abstract: The overall high prevalence of overweight and obesity in the current population is significant and underscores the need for environmental and genetic information that will shed light on the phenomenon of childhood obesity.

Cited by 22 publications

References 33 publications

Ten-Year obesity and overweight prevalence in Greek children: A systematic review and meta-analysis of 2001-2010 data

Ten-Year obesity and overweight prevalence in Greek children: A systematic review and meta-analysis of 2001-2010 data

The combined effect of MC4R and FTO risk alleles on childhood obesity in Greece

Peroxisome proliferator-activated receptor-γ (PPARγ) Pro12Ala polymorphism and risk for pediatric obesity

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