The General Movements in children with Down syndrome

Mazzone, Luigi; Mugno, Diego; Mazzone, D

doi:10.1016/j.earlhumdev.2004.04.013

Cited by 54 publications

(40 citation statements)

References 32 publications

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“…51 GMs evaluation of children with not known motor problems was normal, showing only slight and transient abnormalities at first month. 51 GMs character of children with DS could be related to central nervous system and peripheral abnormalities characterizing this syndrome. 51 The evaluation of GMs in children with DS could be an early marker of motor impairment and help in early management decisions making.…”

Section: General Movements In High-risk Fetuses and Disabled Neonatesmentioning

confidence: 99%

“…50 The same GMs in children with Down syndrome (DS) were characterized by low to low/moderate speed, large to large/ moderate amplitude, partially creating impression of fluency, smoothness and complexity, abrupt beginning and end, and few other concurrent gross movements. 51 During the 6 months, all children showed an improvement of qualitative and semiquantitative evaluation, but it was possible to observe great heterogeneity among children in the evolutionary course. 51 GMs evaluation of children with not known motor problems was normal, showing only slight and transient abnormalities at first month.…”

Section: General Movements In High-risk Fetuses and Disabled Neonatesmentioning

confidence: 99%

“…51 During the 6 months, all children showed an improvement of qualitative and semiquantitative evaluation, but it was possible to observe great heterogeneity among children in the evolutionary course. 51 GMs evaluation of children with not known motor problems was normal, showing only slight and transient abnormalities at first month. 51 GMs character of children with DS could be related to central nervous system and peripheral abnormalities characterizing this syndrome.…”

Section: General Movements In High-risk Fetuses and Disabled Neonatesmentioning

confidence: 99%

“…51 GMs character of children with DS could be related to central nervous system and peripheral abnormalities characterizing this syndrome. 51 The evaluation of GMs in children with DS could be an early marker of motor impairment and help in early management decisions making. 51 The incidence of normal GMs in infants with asymmetric intrauterine growth retardation (IUGR) was lower than in their appropriate for gestational age-matched controls.…”

Section: General Movements In High-risk Fetuses and Disabled Neonatesmentioning

confidence: 99%

“…51 The evaluation of GMs in children with DS could be an early marker of motor impairment and help in early management decisions making. 51 The incidence of normal GMs in infants with asymmetric intrauterine growth retardation (IUGR) was lower than in their appropriate for gestational age-matched controls. 52 Significant correlations were found between GM quality and neurodevelopmental scores in the IUGR group.…”

Section: General Movements In High-risk Fetuses and Disabled Neonatesmentioning

confidence: 99%

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Continuity from Fetal to Neonatal Behavior: Lessons Learned and Future Challenges

Stanojević¹,

Kurjak²

2011

Donald School Journal of Ultrasound in Obstetrics and Gynecology

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Understanding the relation between fetal and infant behavior and developmental processes of the brain in different periods of gestation may make achievable the distinction between normal and abnormal brain development as well as the early diagnosis of various structural or functional abnormalities. As the development of the brain is unique and continuing process throughout the gestation and after birth, it is expected that there is also continuity of fetal and neonatal behavior, which is the best functional indicator of developmental processes of the brain.The aim is to present continuity of the general and other movements from prenatal to postnatal life in fetuses and newborns from lowand high-risk pregnancies.Epidemiological studies revealed that many neurologically impaired infants belong to low-risk population, which means that they seemed to be developmentally normal as fetuses and as infants, while later in childhood neurological disability was diagnosed. Dyskinetic cerebral palsy (CP) is the dominant type of CP found in term-born, appropriate-for-gestational-age children with severe impairments who have frequently experienced adverse perinatal events. As neuroprotective methods of treatment are available for some infants, simple screening methods could be helpful to detect impaired fetuses early enough in order to avoid developmental catastrophe. It has been clear from postnatal assessment of Prechtl's neonatal general movements (GMs) that it is a better predictor of neurodevelopmental disability than neurological examination. Introduction of two-dimensional (2D) and four-dimensional (4D) ultrasound enabled introduction of GMs assessment to the prenatal period. Kurjak et al conducted a study by 4D ultrasound and confirmed earlier findings made by 2D ultrasonography, that there is behavioral pattern continuity from prenatal to postnatal life. New antenatal neurological screening test has been introduced by Kurjak et al (KANET), which was postnatally followed by postnatal neurological screening assessment according to Amiel-Tison (ATNAT). Although many fetal behavioral studies have been conducted in low-and high-risk pregnancies and KANET has been recently standardized, it is still questionable whether the assessment of continuity from fetal to neonatal behavior could improve ability for early detection of brain pathology.

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Section: General Movements In High-risk Fetuses and Disabled Neonatesmentioning

confidence: 99%

Section: General Movements In High-risk Fetuses and Disabled Neonatesmentioning

confidence: 99%

Section: General Movements In High-risk Fetuses and Disabled Neonatesmentioning

confidence: 99%

Section: General Movements In High-risk Fetuses and Disabled Neonatesmentioning

confidence: 99%

Section: General Movements In High-risk Fetuses and Disabled Neonatesmentioning

confidence: 99%

See 3 more Smart Citations

Continuity from Fetal to Neonatal Behavior: Lessons Learned and Future Challenges

Stanojević¹,

Kurjak²

2011

Donald School Journal of Ultrasound in Obstetrics and Gynecology

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Specific grasp characteristics of children with trisomy 21

Jover

Ayoun²,

Berton³

et al. 2010

Developmental Psychobiology

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Children with trisomy 21 display atypical manual skills that change to some extent during development. We examined grasp characteristics and their development in 35 children with trisomy 21, aged 4-18 years, who performed simple manual tasks (two manual tasks of the Movement Assessment Battery for Children, and grasping of five wooden blocks whose size was determined by their hand size). The age-matched comparison group included 35 typically developing children. Children with trisomy 21 were found to use fewer fingers than children in the comparison group in each task. They also used specific grasps and tended to extend fingers that were not involved in the grip. While some specific grasp characteristics of children with trisomy 21 decreased with age, other did not, and remained present throughout development. The perceptual-motor development of children with trisomy 21 should be analyzed in terms of atypical development rather than developmental delay.

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