The genus Cordia: botanists, ethno, chemical and pharmacological aspects

Matias, Edinardo Fágner Ferreira; Alves, Erivania Ferreira; Silva, Maria Karollyna do Nascimento; Carvalho, Victória Regina de Alencar; Coutinho, Henrique Douglas Melo; Costa, José Galberto Martins da

doi:10.1016/j.bjp.2015.05.012

Cited by 57 publications

(52 citation statements)

References 65 publications

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“…americana [63] Heartwood Cordallinol (9) C. alliodora [58] Heartwood Cordiol A (10) C. alliodora [58] Heartwood Cordiaquinol C (11) C. alliodora [58] C. fragrantissima [59] Heartwood Timber Cordiaquinol I (12) C. fragrantissima [59] Timber Cordiaquinol J (13) C. fragrantissima [59] Timber Cordiaquinol K (14)…”

Section: Triterpenoidsmentioning

confidence: 99%

“…The second review published in 2015 was focused on distribution, traditional application and pharmacological activity of the selected plants from the genus Cordia. [9] In the second review, limited data from restricted number of species have been covered; for example, traditional application of 12 species has been incorporated in the review, while a total of 55 chemical constituents isolated from nine species have been included in the review. As the genus Cordia has been studied extensively for its phytochemistry and pharmacological activities, there is a need to discuss the entire scientific data available for ethnomedicinally important species from the genus Cordia in the form of a detailed and systematic review.…”

Section: Introductionmentioning

confidence: 99%

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Traditional uses, phytochemistry and pharmacology of the medicinal species of the genus Cordia (Boraginaceae)

Oza

Kulkarni

2017

Journal of Pharmacy and Pharmacology

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Objectives Cordia (family Boraginaceae) is a genus of deciduous flowering trees or shrubs comprising more than 300 species distributed widely in the tropical regions. The aim of this review was to provide exhaustive scientific information on traditional uses, phytochemistry and pharmacological activities of the 36 important species with medicinal value from the genus Cordia, to divulge prospects for further research on its therapeutic potential. Key findings Leaves, fruit, bark and seed of a majority of the species were found to possess abundant ethnomedicinal value, but leaves were found to be used most frequently to treat many ailments such as respiratory disorders, stomach pain, wound, inflammation, myalgia, cough, dysentery and diarrhoea. The phytochemical investigation of 36 species resulted in isolation of 293 chemical constituents from various chemical classes. The crude extracts, fractions, essential oils and pure compounds isolated from various Cordia species were reported to have a varied range of pharmacological activities. Summary Many of the traditional uses of the genus Cordia were supported by the results obtained from pharmacological studies performed using various extracts or pure compounds. More attention should be given to the biological evaluation using pure phytochemicals and to identify the mechanism of actions and exploring this genus for new drug discovery.

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Section: Triterpenoidsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Traditional uses, phytochemistry and pharmacology of the medicinal species of the genus Cordia (Boraginaceae)

Oza

Kulkarni

2017

Journal of Pharmacy and Pharmacology

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“…Plants of genus Cordia are highly reputed for their diverse pharmacology and phytochemistry (Matias et al 2015). However, C. rothii is relatively less explored specie.…”

Section: Discussionmentioning

confidence: 99%

“…Cordia (Boraginaceae) is well known for its phytochemical and pharmacological diversity (Matias et al 2015). Cordia rothii Roem.…”

Section: Introductionmentioning

confidence: 99%

GC-MS profile of antimicrobial and antioxidant fractions fromCordia rothiiroots

Khan

Firdous

Ahmad

et al. 2016

Pharmaceutical Biology

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Context: An ethnobotanical survey of Cordia rothii Roem. & Schult. (Boraginaceae) reveals it as a medicinal plant. Objective: Antimicrobial and antioxidant potential evaluation and identification of chemical constituents via GC-MS of C. rothii roots fractions. To the best of our knowledge, this is the first systematic investigation of the roots exploiting GC-MS. Materials and methods: Extraction and fractionation of C. rothii roots furnished various fractions using solvents of varying polarity, i.e., n-hexane, chloroform, ethyl acetate, acetone and methanol. In vitro antimicrobial and antioxidant screening was performed using disk diffusion and DPPH methods, respectively. MIC of active fractions was also determined using disk diffusion method. GC-MS was used to identify constituents which may be responsible for these activities. Results: Among various fractions from C. rothii roots, fraction KA-C showed strong antibacterial activity against 17 microorganisms tested, with MIC ranging from 250-31.25 lg/mL. Fractions KA-A, KM and KM-A exhibited significant antioxidant potential with EC 50 46.875 lg/mL, while fractions KEA-PE, KM-PE and KM-M were good with EC 50 93.750 lg/mL. Forty-five phytochemicals were identified in GC-MS studies including eight hydrocarbons, six free fatty acids, 11 fatty acids esters, two phenylpropanoids, four aromatics, four terpenoid quinones/hydroquinones, three triterpenes, four phytosterols, two hexose metabolites and a DNA base. Of these, 32 constituents have been reported for the first time from C. rothii, 24 from genus Cordia and 15 from Boraginaceae. Discussion and conclusion: Strong antibacterial and antioxidant potential of C. rothii roots may be due to the contribution of phytoconstituents identified through GC-MS studies.ARTICLE HISTORY

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“…The genus Cordia including almost 250 species, occur in various Asian and African continents [2] and native to the Americas, [3]. C. myxa fruits is described in popular medicine as laxative and cough medicine in pulmonary diseases [4].…”

Section: Introductionmentioning

confidence: 99%

Anatomical study of vegetative parts and Powder microscopy of Cordia myxa L. (Boraginaceae) in Iraq

2016

IJACEBS

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Abstract-This study deals with the anatomical features of Cordia myxa stem, leaf and petiole in Iraq. Peeling method have been clarified anomocytic stomata with anticlinal walls of epidermal cells, the cross sections of lamina shown the unicellular epidermis in abaxial and adaxial surface, unicellular trichomes spread in the epidermis. adaxial covered by thick cuticle, bifacial mesophyll. idioblasts spread through palisade parenchyma, oval to circular shape cells of spongy parenchyma, midrib have large concentric vascular bundle is present at the midrib region and one vascular bundle in above. Petiole shape is square with five vascular bundle appear, the big one located on the central and four vascular bundle located in the corners. The dried leaf powder was brown to green in color, microscopy of the powder showed fragments of unicellular trichomes, stomata, fibers, crystal differ in shape like as regular prismatic, druses, sand crystal, and dendritic crystal like as snowflake formation in shape

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The genus Cordia: botanists, ethno, chemical and pharmacological aspects

Cited by 57 publications

References 65 publications

Traditional uses, phytochemistry and pharmacology of the medicinal species of the genus Cordia (Boraginaceae)

Traditional uses, phytochemistry and pharmacology of the medicinal species of the genus Cordia (Boraginaceae)

GC-MS profile of antimicrobial and antioxidant fractions fromCordia rothiiroots

Anatomical study of vegetative parts and Powder microscopy of Cordia myxa L. (Boraginaceae) in Iraq

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