The genus Polyscias (Araliaceae): A phytochemical and biological review

Ashmawy, Naglaa S.; Gad, Haidy A.; Ashour, Mohamed L.; El-Ahmady, Sherweit H.; Singab, Abdel Nasser B.

doi:10.1016/j.hermed.2020.100377

Cited by 15 publications

(18 citation statements)

References 34 publications

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“…However, its phytochemical constituents are not fully recognized. It was reported that the leaves and roots are abundant sources of triterpenoid saponins [ 19 ], whose presence was also confirmed in other Polyscias species [ 20 ]. Interestingly, oleanolic acid glycosides have been determined in cell suspension cultures of P. filicifolia , but only those established from callus developed directly on leafy explants.…”

Section: Introductionmentioning

confidence: 84%

In Vitro Response of Polyscias filicifolia (Araliaceae) Shoots to Elicitation with Alarmone–Diadenosine Triphosphate, Methyl Jasmonate, and Salicylic Acid

Śliwińska

Naliwajski

Pietrosiuk

et al. 2021

Cells

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The effectiveness of different elicitation variants in combination with alarmone application was studied in shoot cultures of Polyscias filicifolia. The shoots were elicited with 200 µM methyl jasmonate (MeJA) or 50 µM salicylic acid (SA) alone or in combination, and their activity was compared with those treated with the alarmone diadenosine 5′,5‴-P1P3-triphosphate (Ap3A), either alone or in combination with SA and/or MeJA. All treatments resulted in significant stimulation of phenolic acid production (chlorogenic and ferulic acids), as well as oleanolic acid (OA) compared to control, with their highest concentration noted under simultaneous elicitation with SA and MeJA. While the maximum content of caffeic acid was detected after treatment with alarmone alone. In each of the culture variants enhanced antioxidant activity was observed, however the level varied according to the treatment. In addition, the SA, Ap3A and Ap3A+SA variants demonstrated additional peroxidase isoforms, as indicated by Native-PAGE, as well as the highest α-tocopherol content. The highest antioxidant capacity of shoot extracts was correlated with the highest abundance of phenolic compounds and OA. The results indicate that ROS induction appears to participate in the signal transduction following Ap3A treatment.

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Section: Introductionmentioning

confidence: 84%

In Vitro Response of Polyscias filicifolia (Araliaceae) Shoots to Elicitation with Alarmone–Diadenosine Triphosphate, Methyl Jasmonate, and Salicylic Acid

Śliwińska

Naliwajski

Pietrosiuk

et al. 2021

Cells

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“…One of the plants from the Araliaceae family that has been scientifically proven related to its activity against a disease, namely, the Mangkokan leaf (Nothopanax scutellarium [Burm.f] Merr.). such as calcium, oxalate, peroxidase, amygdalin, phosphorus, iron, fat, protein, Vitamins A, B1, C, saponins, tannins, flavonoids, alkaloids, and terpenoids [2], [3], [4]. Meanwhile, it has been scientifically proven that the leaves of the Mangkokan have anti-fungal activity [6], antioxidant [3], antibacterial [5], and wound healing.…”

Section: Introductionmentioning

confidence: 99%

Determination of Total Flavonoid Level and Antioxidant Activity of Ethyl Acetate Fraction of Mangkokan Leaf Extract (Nothopanax scutellarium [Burm.f] Merr.)

Nasution

Ginting

Lister

2022

Open Access Maced J Med Sci

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Mangkokan leaves (Nothopanax scutellarium (Burm.f) Merr.) have several properties, containing several chemicals that have bioactivity. It contains flavonoids and is a natural source of antioxidants. This study aims to determine the total flavonoid content and the potency of the ethyl acetate fraction in the leaves of the Mangkokan leaf as an antioxidant in counteracting free radicals. Identification of flavonoids was carried out with a reagent between magnesium powder and concentrated HCl, the orange color formed indicated the presence of flavonoids. Determination of the total flavonoid content of the ethyl acetate fraction of the Mangkokan leaf extract was carried out colorimetrically using a UV-Vis spectrophotometer. The antioxidant activity test of the ethyl acetate fraction of kukukan leaf extract was carried out using the DPPH (1,1-diphenyl-2-picrylhydrazyl) method. The results showed that the total flavonoid content of the ethyl acetate fraction of the Mangkokan leaf extract was 25.402749 mgGAE/g extract and the free radical inhibition test with the DPPH method showed that the ethyl acetate fraction of the Mangkokan leaf extract had antioxidant activity with an IC50 value of 103.36 ppm. The ethyl acetate fraction of the Mangkokan leaf extract has activity as an antioxidant with a moderate category of antioxidant power so that it has the potential to be developed in the treatment of diseases caused by free radicals.

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“…Bailey is a representative of the Araliaceae family. P. filicifolia is a species that shares the genus Polyscias with between 116 [ 1 ] and 150 others [ 2 ]. It is an evergreen, six-meter-tall shrub that naturally occurs in Southeast Asia, but is also available as a decorative potted plant [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

“…Polyscias spp. extracts may also contain polyphenols, flavonoids, glycosides, saponins, cyanogenic glycosides, sterols and alkaloids [1,4,6,7]. In Southeast Asia, plants of Polyscias genus are broadly used in traditional medicine; for example, it is recorded in the official Vietnamese Pharmacopoeia as an anti-fatigue and cardiac drug [8].…”

Section: Introductionmentioning

confidence: 99%

Comparative Study of the Genetic and Biochemical Variability of Polyscias filicifolia (Araliaceae) Regenerants Obtained by Indirect and Direct Somatic Embryogenesis as a Source of Triterpenes

Śliwińska

Białek

Orłowska

et al. 2021

IJMS

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Polyscias filicifolia (Araliaceae) is broadly used in traditional medicine in Southeast Asia due to its antimicrobial, immunomodulating and cytotoxic activities. The main groups of compounds responsible for pharmacological effects are believed to be oleanolic triterpene saponins. However, Polyscias plants demonstrate relatively slow growth in natural conditions, which led to applying a developing sustainable source of plant material via primary (PSE), secondary (DSE) and direct somatic embryogenesis from DSE (TSE). The AFLP and metAFLP genotyping resulted in 1277 markers, amplified by a total of 24 pairs of selective primers. Only 3.13% of the markers were polymorphic. The analysis of variance showed that the PSE and TSE regenerants differed only in terms of root number, while the DSE plantlets differed for all studied morphological characteristics. Further, the chemical analysis revealed that oleanolic acid (439.72 µg/g DW), ursolic acid (111.85 µg/g DW) and hederagenin (19.07 µg/g DW) were determined in TSE regenerants. Our results indicate that direct somatic embryogenesis ensures the production of homogeneous plant material, which can serve as a potential source of triterpene compounds. Plants obtained via somatic embryogenesis could also be reintroduced into the natural environment to protect and preserve its biodiversity.

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The genus Polyscias (Araliaceae): A phytochemical and biological review

Cited by 15 publications

References 34 publications

In Vitro Response of Polyscias filicifolia (Araliaceae) Shoots to Elicitation with Alarmone–Diadenosine Triphosphate, Methyl Jasmonate, and Salicylic Acid

In Vitro Response of Polyscias filicifolia (Araliaceae) Shoots to Elicitation with Alarmone–Diadenosine Triphosphate, Methyl Jasmonate, and Salicylic Acid

Determination of Total Flavonoid Level and Antioxidant Activity of Ethyl Acetate Fraction of Mangkokan Leaf Extract (Nothopanax scutellarium [Burm.f] Merr.)

Comparative Study of the Genetic and Biochemical Variability of Polyscias filicifolia (Araliaceae) Regenerants Obtained by Indirect and Direct Somatic Embryogenesis as a Source of Triterpenes

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