The good, the bad, and the ugly about surgical approaches for inflatable penile prosthesis implantation

Otero, Javier; Manfredi, Celeste; Wilson, Steven K.

doi:10.1038/s41443-020-0319-4

Cited by 26 publications

(28 citation statements)

References 34 publications

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“…Oral PDE5Is, intracavernous or topical alprostadil, vacuum devices, and penile prostheses are some therapeutic options for ED. [17][18][19][20] Non-steroidal anti-inflammatory drugs (NSAIDs), penile traction therapy (PTT), collagenases, and shortening or lengthening surgical procedures are some treatment options for PD. [21][22][23][24] In recent years, ESWT has proven to be an effective treatment in selected patients with ED and PD, to improve erectile function and relieve penile pain, respectively.…”

Section: Discussionmentioning

confidence: 99%

Impact of extracorporeal shockwave therapy for erectile dysfunction and Peyronie's disease on reproductive and hormonal testicular function

et al. 2022

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Introduction: Extracorporeal shock wave therapy is an established treatment for erectile dysfunction and Peyronie's disease. Concerns regarding the safety of extracorporeal shock wave therapy for andrological purposes on testicular function were raised by animal studies. Aim: To evaluate the impact of extracorporeal shock wave therapy for erectile dysfunction or Peyronie's disease on reproductive and hormonal testicular function. Methods: We designed a prospective controlled study in which consecutive patients were enrolled. Males aged between 18 and 40 years with mild vasculogenic erectile dysfunction or acute inflammatory Peyronie's disease and normozoospermia were included. All enrolled patients were offered extracorporeal shock wave therapy, and subjects who refused extracorporeal shock wave therapy for any reason were considered as the Control group. All patients in the Intervention group were treated with DUOLITH SD1 T-TOP by a single expert urologist. Semen analysis and serum total testosterone dosage were performed before the start (T0) and 3 months after the end of extracorporeal shock wave therapy (T1) in Intervention group. The same parameters were evaluated after the extracorporeal shock wave therapy refusal (T0) and at the end of the following 3 months (T1) in Control group. Normozoospermia wasThis is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Section: Discussionmentioning

confidence: 99%

Impact of extracorporeal shockwave therapy for erectile dysfunction and Peyronie's disease on reproductive and hormonal testicular function

et al. 2022

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“…There are many different techniques of penile prosthesis, but the most used approaches are mainly three as follows: the infrapubic approach, first applied by Scott in 1972, the penoscrotal approach, first described by Barry and Scott in 1979, and the subcoronal approach, popularized by Egidio in 2016 [18].…”

Section: Surgical Approachmentioning

confidence: 99%

“…The penoscrotal approach seems to be more indicated in case of corporal fibrosis, mainly secondary to prior implant removal due to infection, as it allows more complete access to the corpora proximally and distally. About subcoronal approach, excellent visibility of corpora cavernosa and urethra are guaranteed and additional surgical reconstructive procedure, such as Peyronie's disease, can be easily performed; however, it requires more oper-ative time, compared to the two other techniques, and the degloving of the penis may cause sensorial alteration or skin loss; it is also limited by the number of studies about the surgical approach and the follow [13,18].…”

Section: Comparison Between the Three Techniquesmentioning

confidence: 99%

Erectile Dysfunction, Surgical and Regenerative Therapy

Bettocchi

Castiglione

Çakır

et al. 2022

Practical Clinical Andrology

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Erectile dysfunction (ED) is defined as the failure to achieve and/or maintain a penile erection that is satisfactory for sexual intercourse.The implantation of a penile prosthesis may be considered in patients who are not suitable for different pharmacotherapies and do not respond to the first and the second line of medical treatment.Intraoperative complications include hematoma formation, floppy glans, perforation of the corpora cavernosa, and urethral injury. Bladder, vascular, and bowel injury are the most dangerous events and should be prevented. Postoperative complications are represented by infections, erosions, and glandular ischemia.There is an increasing interest in the hypothesis of “regenerative” cures for ED aimed at decreasing fibrosis of the corpora cavernosa and rebuilding their normal biological architecture. These new regenerative treatments include stem cell injections, platelet-rich plasma, and low-intensity shock wave therapy.

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“…In addition, intracavernous injection therapy using vasodilators can be used, and a penile prosthesis can be inserted if the patient agrees to surgical treatment owing to a poor response to other treatments. A high satisfaction rate has been reported after penile-prosthesis surgery [ 8 , 9 ]. Therefore, functional and structural rearrangements of the damaged penile neurovascular system are necessary to overcome ED after RP [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

Efficacy of Low-Intensity Extracorporeal Shock Wave Treatment in Erectile Dysfunction Following Radical Prostatectomy: A Systematic Review and Meta-Analysis

Rho

Kim

Ryu

et al. 2022

JCM

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Erectile dysfunction (ED) is a well-known complication of radical prostatectomy (RP). Oral 5-phosphodiesterase inhibitors are currently the most widely used penile rehabilitation treatment for ED following RP, but they are less effective than for those with general ED. Low-intensity extracorporeal shock wave treatment (LI-ESWT), causing a biological change that induces neovascularization, has recently been used as a treatment for ED. Therefore, we conducted a systematic review and meta-analysis to investigate the efficiency of LI-ESWT in ED following RP. PubMed, Embase, and the Cochrane Library were searched up until December 2021. The endpoint was the change in IIEF scores after LI-ESWT. Five papers (460 patients) were included in the final analysis. In IIEF scores performed 3–4 months after LI-ESWT, the group receiving LI-ESWT showed statistically significantly better results than the control (WMD = −2.04; 95% CI, −3.72 to −0.35; p = 0.02). However, there were a total of two studies that measured the results after 9–12 months. There was no statistical difference between the two groups (WMD = −5.37; 95% CI, −12.42 to 1.69; p = 0.14). The results of this analysis indicate that LI-ESWT showed a statistically significant effect on early recovery in penile rehabilitation of ED following RP. However, the level of evidence was low. Therefore, careful interpretation of the results is required.

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The good, the bad, and the ugly about surgical approaches for inflatable penile prosthesis implantation

Cited by 26 publications

References 34 publications

Impact of extracorporeal shockwave therapy for erectile dysfunction and Peyronie's disease on reproductive and hormonal testicular function

Impact of extracorporeal shockwave therapy for erectile dysfunction and Peyronie's disease on reproductive and hormonal testicular function

Erectile Dysfunction, Surgical and Regenerative Therapy

Efficacy of Low-Intensity Extracorporeal Shock Wave Treatment in Erectile Dysfunction Following Radical Prostatectomy: A Systematic Review and Meta-Analysis

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