While the GDPR and other EU laws seek to mitigate a range of potential harms associated with smart cities, the compliance with and enforceability of these regulations remain an issue. In addition, these proposed regulations do not sufficiently address the collective harms associated with the deployment of biometric technologies and artificial intelligence. Another relevant question is whether the initiatives put forward to secure fundamental human rights in the digital realm account for the issues brought on by the deployment of technologies in city spaces. In this special issue, we employ the smart city notion as a point of connection for interdisciplinary research on the human rights implications of the algorithmic, biometric and smart city technologies and the policy responses to them. The articles included in the special issue analyse the latest European regulations as well as soft law, and the policy frameworks that are currently at work in the regions where the GDPR does not apply.