2016
DOI: 10.1016/j.jnutbio.2015.08.011
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The gut microbial community in metabolic syndrome patients is modified by diet

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Cited by 179 publications
(142 citation statements)
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“…In line with these results, FRD-fed mice supplemented with L. kefiri showed an increase in B. fragilis , but no changes in Clostridium coccoides group, accompanied by an improvement of several metabolic alterations caused by FRD intake. Some reports have described beneficial effects of B. fragilis , including preventive effects against colitis and intestinal inflammation [69,70], and improvement in plasma levels of triglycerides and glucose [71]. Furthermore, we found that L. murinus population was higher in FRD-Lk and CTR-Lk mice.…”
Section: Discussionsupporting
confidence: 62%
“…In line with these results, FRD-fed mice supplemented with L. kefiri showed an increase in B. fragilis , but no changes in Clostridium coccoides group, accompanied by an improvement of several metabolic alterations caused by FRD intake. Some reports have described beneficial effects of B. fragilis , including preventive effects against colitis and intestinal inflammation [69,70], and improvement in plasma levels of triglycerides and glucose [71]. Furthermore, we found that L. murinus population was higher in FRD-Lk and CTR-Lk mice.…”
Section: Discussionsupporting
confidence: 62%
“…However, human studies have yielded inconsistent results, including a reduced abundance of Firmicutes in obese subjects . Previous data indicate that the variability of human population, related with factor such as age or gender, seems to affect gut microbiota composition . We hypothesized that the microbiota profile of obese people could differ according to their metabolic status, which could also help to explain the discrepancy found in obese people, where the proportion of obese people with and without metabolic diseases may correspond more or less to the degree of dysbiosis of gut microbiota.…”
Section: Introductionmentioning
confidence: 94%
“…Similar results were found in two qPCR studies in Japanese and Danish adults with T2DM, when compared to healthy individuals (116, 120). In addition, higher Lactobacillus abundance was found in participants diagnosed with MetS (23). These findings support the study by Armougom et al (96) suggesting a positive association of high abundance of Lactobacilli with obesity and its implications.…”
Section: Lactobacillusmentioning
confidence: 99%
“…Only a negative relation between waist circumference and the relative abundance of Bacteroides thetaiotaomicron was observed ( R  = 0.162, P  = 0.022). It must be noted that the non-MetS group in this trial did not include healthy individuals, but individuals with a history of coronary heart disease that were involved in another clinical trial at the time (23). Furthermore, a higher abundance of Bacteroides has been reported to be associated with impaired glucose tolerance in T2DM patients as well (103).…”
Section: Bacteroidesmentioning
confidence: 99%