The hemolymph proteome of Anopheles gambiae

Paskewitz, Susan M.; Shi, Lei

doi:10.1016/j.ibmb.2005.03.002

Cited by 67 publications

(56 citation statements)

References 71 publications

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“…The up-regulation of actin A2 (spot 863) was possibly an aphid tissue repair response, being observed in the resistant aphid 4 d post-attack by A. ervi, where a parasitoid rarely developed. Abundant muscle actin was also observed previously in physically wounded Drosophila (Vierstraete et al, 2004) and Anopheles (Paskewitz and Shi, 2005).…”

Section: Cytoskeleton Proteinssupporting

confidence: 79%

Proteomes of the aphid Macrosiphum euphorbiae in its resistance and susceptibility responses to differently compatible parasitoids

Nguyen

Boudreault

Michaud

et al. 2008

Insect Biochemistry and Molecular Biology

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Section: Cytoskeleton Proteinssupporting

confidence: 79%

Proteomes of the aphid Macrosiphum euphorbiae in its resistance and susceptibility responses to differently compatible parasitoids

Nguyen

Boudreault

Michaud

et al. 2008

Insect Biochemistry and Molecular Biology

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“…This same protein previously was identified as a constitutive hemolymph protein (Paskewitz and Shi, 2005).…”

Section: Secreted Proteins Other Than Structural Cuticular Proteinsmentioning

confidence: 62%

Proteomic analysis of cast cuticles from Anopheles gambiae by tandem mass spectrometry

Botelho

McNall

et al. 2007

Insect Biochemistry and Molecular Biology

112

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“…Drosophila melanogaster is the best studied among them as researchers have worked to elucidate the hemolymph proteomes of healthy flies (9 -11) as well as postinjury (12) and immunechallenged flies (13)(14)(15)(16). Mass spectrometry-based hemolymph studies have also been conducted for species as diverse as Helicoverpa armigera (moth) (17), Bombyx mori (silkworm) (18), Amblyomma hebraeum (tick) (19), and Anopheles gambiae (mosquito) (20,21).…”

mentioning

confidence: 99%

Quantitative Comparison of Caste Differences in Honeybee Hemolymph

Chan¹,

Howes

Foster

2006

Molecular & Cellular Proteomics

147

177

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The honeybee, Apis mellifera, is an invaluable partner in agriculture around the world both for its production of honey and, more importantly, for its role in pollination. Honeybees are largely unexplored at the molecular level despite a long and distinguished career as a model organism for understanding social behavior. Like other eusocial insects, honeybees can be divided into several castes: the queen (fertile female), workers (sterile females), and drones (males). Each caste has different energetic and metabolic requirements, and each differs in its susceptibility to pathogens, many of which have evolved to take advantage of the close social network inside a colony. Hemolymph, arthropods' equivalent to blood, distributes nutrients throughout the bee, and the immune components contained within it form one of the primary lines of defense against invading microorganisms. In this study we have applied qualitative and quantitative proteomics to gain a better understanding of honeybee hemolymph and how it varies among the castes and during development. We found large differences in hemolymph protein composition, especially between larval and adult stage bees and between male and female castes but even between adult workers and queens. We also provide experimental evidence for the expression of several unannotated honeybee genes and for the detection of biomarkers of a viral infection. Our data provide an initial molecular picture of honeybee hemolymph, to a greater depth than previous studies in other insects, and will pave the way for future biochemical studies of innate immunity in this animal.

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The hemolymph proteome of Anopheles gambiae

Cited by 67 publications

References 71 publications

Proteomes of the aphid Macrosiphum euphorbiae in its resistance and susceptibility responses to differently compatible parasitoids

Proteomes of the aphid Macrosiphum euphorbiae in its resistance and susceptibility responses to differently compatible parasitoids

Proteomic analysis of cast cuticles from Anopheles gambiae by tandem mass spectrometry

Quantitative Comparison of Caste Differences in Honeybee Hemolymph

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