The histology and the proapoptotic control in the ipsilateral and the contralateral testes following unilateral vasectomy

Hazar, Aydin Ismet; Çakıroğlu, Basri; Sakalli, Ertan; Balci, Mustafa Bahadır Can; Eyyupoglu, Erkan; Taş, Tuncay; Sinanoğlu, Orhun; Tuzlali, Pinar; Çilesiz, Nusret Can

doi:10.4081/aiua.2015.3.198

Cited by 2 publications

(2 citation statements)

References 38 publications

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“…As expected, the remarks made in the case of human patients apply to rodents as well. Seminal obstruction, regardless of the testes and side, reduces the rate of spermatogenesis, concluding that unilateral vasectomy induces vast histological changes that cover unilateral obstruction, intratubular germ cell necrosis, and an increase in tubular pressure probably linked to autoimmune responses [ 176 ].…”

Section: Resultsmentioning

confidence: 99%

A Narrative Review Discussing Vasectomy-Related Impact upon the Status of Oxidative Stress and Inflammation Biomarkers and Semen Microbiota

Doroftei

Ilie

Maftei

et al. 2023

JCM

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Background: Male contraceptive approaches besides tubal sterilization involve vasectomy and represent the method of choice among midlife men in developing countries thanks to many advantages. However, the subsidiary consequences of this intervention are insufficiently explored since the involved mechanisms may offer insight into a much more complex picture. Methods: Thus, in this manuscript, we aimed to reunite all available data by searching three separate academic database(s) (PubMed, Web of Knowledge, and Scopus) published in the past two decades by covering the interval 2000–2023 and using a predefined set of keywords and strings involving “oxidative stress” (OS), “inflammation”, and “semen microbiota” in combination with “humans”, “rats”, and “mice”. Results: By following all evidence that fits in the pre-, post-, and vasectomy reversal (VR) stages, we identified a total of n = 210 studies from which only n = 21 were finally included following two procedures of eligibility evaluation. Conclusions: The topic surrounding this intricate landscape has created debate since the current evidence is contradictory, limited, or does not exist. Starting from this consideration, we argue that further research is mandatory to decipher how a vasectomy might disturb homeostasis.

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Section: Resultsmentioning

confidence: 99%

A Narrative Review Discussing Vasectomy-Related Impact upon the Status of Oxidative Stress and Inflammation Biomarkers and Semen Microbiota

Doroftei

Ilie

Maftei

et al. 2023

JCM

View full text Add to dashboard Cite

show abstract

“…It has been suggested that seminal obstruction on one side might reduce the rate of spermatogenesis, thus indicating that unilateral vasectomy is not an ideal modality for the treatment of epididymitis with PUCs [15]. Once PUCs have been excised, anatomical reconstruction of the seminal passage appears to be a far superior option than other techniques.…”

Section: Resultsmentioning

confidence: 99%

Robot Surgery for Midline Cysts of the Prostate With Hypospadias in the Pediatric Population

Qin

Wang

et al. 2022

Urology

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This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

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The histology and the proapoptotic control in the ipsilateral and the contralateral testes following unilateral vasectomy

Abstract: The procedure causes destruction in the testicular structure by causing bilateral intratubular germ cell necrosis, unilateral obstruction, increase in the tubular pressure and processes that are aggravated by some probable autoimmune reactions.

Cited by 2 publications

References 38 publications

A Narrative Review Discussing Vasectomy-Related Impact upon the Status of Oxidative Stress and Inflammation Biomarkers and Semen Microbiota

A Narrative Review Discussing Vasectomy-Related Impact upon the Status of Oxidative Stress and Inflammation Biomarkers and Semen Microbiota

Robot Surgery for Midline Cysts of the Prostate With Hypospadias in the Pediatric Population

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