The histology of nasopharyngeal masses: a comparison between HIV positive and HIV negative patients

Erasmus, T.; Daniller, T.; Goedhals, Jacqueline; Joubert, Gina; Seedat, Riaz Y.

doi:10.1007/s00405-012-2192-3

Cited by 6 publications

(2 citation statements)

References 16 publications

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“…Most nasopharyngeal masses in HIV positive patients were benign. Malignancies were significantly more common in the HIV negative group than in the HIV positive group (10). On the contrary, Maruyama et al (11) believed that most tumors that occur in the nasopharynx are malignant, which was in concordance with our results.…”

Section: Discussionmentioning

confidence: 99%

Ten years of experience in clinicopathologic characteristics, treatment and outcome of patients with nasopharyngeal pathologies in Yazd, Iran

Binesh¹,

Shajari²,

Abdollahi³

et al. 2016

Electron physician

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IntroductionAlthough there are some studies regarding the clinical characteristics and outcome of nasopharyngeal tumors, one such study from Iran has not been reported to date. This study aimed to evaluate the clinical features, treatment, and consequences of nasopharyngeal lesions.MethodsIn this cross sectional study, we conducted a retrospective review of patients who were diagnosed with nasopharyngeal pathologies and treated at Shahid Sadoughi Hospital and Shahid Ramazanzadeh Radiotherapy Center in Yazd, Iran, over a period of 10 years (from 2005 to 2014). The variables in the study were the patient’s hospital registration number, date, name, age, gender, address, topography, clinical symptoms, morphology, stage, types of treatment, and survival for each subject. Survival data were analyzed using Kaplan-Meier estimates, and multivariate analysis was performed using the Cox regression method. Statistical analyses were performed using IBM-SPSS, version 22.ResultsIn the study, there were 123 patients, 85 males and 38 females, who had nasopharyngeal lesions. The mean age at diagnosis was 41.51 ± 20.33 years. There were 83 patients with malignant neoplasms and 40 patients with non-malignant lesions. The most common malignant tumor was nasopharyngeal carcinoma, and the most common benign lesion was angiofibroma. Survival analysis was performed for the 83 patients who had malignant neoplasms, and survival was found to be 94.5 ± 4.32 months. There were significant differences in survival based on the stage of the disease, histological type, and the type of treatment (p = 0.001, 0.02, and 0.003, respectively).ConclusionIn our institutional study, malignant tumors were more common than benign lesions. Patients with nasopharyngeal carcinoma presented relatively late and at an advanced stage. Regular follow-up is necessary for early detection, recurrence, or metastases of malignant tumors.

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Section: Discussionmentioning

confidence: 99%

Ten years of experience in clinicopathologic characteristics, treatment and outcome of patients with nasopharyngeal pathologies in Yazd, Iran

Binesh¹,

Shajari²,

Abdollahi³

et al. 2016

Electron physician

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“…The results indicate a lower overall mean age of people with NPC and then OC and OPC with the highest overall mean age for people with HPC and LC. A potential reason for a lower mean age for the NPV group could be that HIV was prevalent in two of the three studies in Ghana, 17 Ethiopia 18 and South Africa, 19 indicating that people with HIV and NPC presented at a younger age.…”

Section: Review Findingsmentioning

confidence: 99%

Epidemiology and demographics of head and neck cancer in Africa: A scoping review

Seedat

Coutts

Vlok

2023

African Journal of Primary Health Care & Family Medicine

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Background Low- to middle-income countries account for 70% of global cancer deaths. Evidence of the changing prevalence of head and neck cancer in Africa in terms of gender, race and epidemiology will inform future research and health planning. Aim To synthesise epidemiological literature for head and neck cancer in Africa from 2010 to 2020. Method A scoping review was completed. The Joanna Briggs Institute Population, context and concept framework confirmed the inclusion criteria. Studies from Africa that included participant demographics, the types, stages, signs and symptoms of head and neck cancer were selected. Five databases were used. Descriptive statistics was completed. Results The Preferred Reporting Items for Systematic Reviews and MetaAnalysis guided the reporting of the findings. Of the 1891 articles downloaded, 66 were included in the final review. Nigeria produced the most studies and oral cancer at 74% was most prevalent. Substance abuse was the most prevalent cause. Diagnosis of head and neck cancers were in the late stage (stage IV) when signs and symptoms were severe. Males of lower socioeconomic status tended to have less health seeking behaviour. Conclusion Countries from North Africa produce the most research outputs on head and neck cancers. Gender differences were noted and may be linked to lifestyle choices. A range of head and neck cancers (HNCs) are prevalent however late diagnosis and severe symptomatology impact treatment options. Contribution Earlier diagnosis and intervention to prevent late-stage diagnosis is necessary. Awareness campaigns linked to evidence on causes, habits and lifestyle choices, signs and symptoms are needed.

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Rebound adenotonsillar and thymic uptake of 18F-FDG in paediatric patients with lymphoma

Zhao

Zhang

et al. 2020

European Journal of Radiology

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The histology of nasopharyngeal masses: a comparison between HIV positive and HIV negative patients

Cited by 6 publications

References 16 publications

Ten years of experience in clinicopathologic characteristics, treatment and outcome of patients with nasopharyngeal pathologies in Yazd, Iran

Ten years of experience in clinicopathologic characteristics, treatment and outcome of patients with nasopharyngeal pathologies in Yazd, Iran

Epidemiology and demographics of head and neck cancer in Africa: A scoping review

Rebound adenotonsillar and thymic uptake of 18F-FDG in paediatric patients with lymphoma

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