The histories of withdrawal convulsions and delirium tremens in 1648 alcohol dependent subjects

Schuckit, Marc A.; Tipp, Jayson E.; Reich, Theodore; Hesselbrock, Victor; Bucholz, Kathleen K.

doi:10.1111/j.1360-0443.1995.tb03551.x

Cited by 132 publications

(87 citation statements)

References 45 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…14,15 Delirium during alcohol withdrawal is predicted by the following: CIWA-Ar scores above 15 (especially in association with a systolic blood pressure >150 mm Hg or a pulse rate >100 beats per minute), recent withdrawal seizures (seen in 20% of persons with delirium), prior withdrawal delirium or seizures, older age, recent misuse of other depressant agents, and concomitant medical problems. 7,10,11,13,16,17 The latter include electrolyte abnormalities (e.g., low levels of potassium, magnesium, or both), low platelet counts, and respiratory, cardiac, or gastrointestinal disease. 7,10,11,17 Tr e atment of W ithdr awa l Delir ium…”

Section: Withdrawal Delirium (Delirium Tremens)mentioning

confidence: 99%

“…7,10,11,13,16,17 The latter include electrolyte abnormalities (e.g., low levels of potassium, magnesium, or both), low platelet counts, and respiratory, cardiac, or gastrointestinal disease. 7,10,11,17 Tr e atment of W ithdr awa l Delir ium…”

Section: Withdrawal Delirium (Delirium Tremens)mentioning

confidence: 99%

“…9,17 The same general types of support needed for any patient with delirium should be used for the patient with withdrawal delirium, including helping to reorient the patient to time, date, and place, evaluating and treating the patient in a well-lit room, providing reassurance, performing frequent monitoring of vital signs, and ensuring adequate hydration. A functioning intravenous line should be established; care should be taken when administering glucose to avoid precipitating Wernicke's encephalopathy or thiamine-related cardiomyopathies and to circumvent overhydration in patients who have temporary, alcohol-related, compromised cardiac functioning.…”

Section: Components Of Scale Most Severe Manifestationsmentioning

confidence: 99%

See 2 more Smart Citations

Recognition and Management of Withdrawal Delirium (Delirium Tremens)

2014

Self Cite

View full text Add to dashboard Cite

A t some time in their lives, 20% of men and 10% of women in most Western societies will have an alcohol-use disorder, which is defined as repetitive alcohol-related problems in at least 2 of 11 areas of life. 1,2 These conditions can decrease the life span by a decade and are associated with severe impairments in social functioning, as well as high rates of medical problems. Although alcohol-related conditions occur in persons from all social strata and affect more than 20% of patients in most medical settings, 2,3 few physicians have been adequately trained in identifying and treating these serious problems.About 50% of persons with alcohol-use disorders have symptoms of alcohol withdrawal when they reduce or discontinue their alcohol consumption; in 3 to 5% of these persons, grand mal convulsions, severe confusion (a delirium), or both develop. 1 It is essential that clinicians know how to prevent, recognize, and treat these severe withdrawal states to minimize costly hospitalizations and avoidable deaths.

show abstract

Section: Withdrawal Delirium (Delirium Tremens)mentioning

confidence: 99%

Section: Withdrawal Delirium (Delirium Tremens)mentioning

confidence: 99%

Section: Components Of Scale Most Severe Manifestationsmentioning

confidence: 99%

See 1 more Smart Citation

Recognition and Management of Withdrawal Delirium (Delirium Tremens)

2014

Self Cite

View full text Add to dashboard Cite

show abstract

“…At departments specializing in alcohol dependence treatment, the rate of delirium tremens was 5-11% (ref. 18,19 ). In the Finnish population, the lifetime prevalence of alcohol-induced delirium was 0.18% (95% CI 0.11-0.32%) (ref.…”

Section: Prevalencementioning

confidence: 99%

“…Delirium tremens usually develops in individuals with a history of long-term and heavy drinking 19,20 .…”

Section: Etiopathogenesismentioning

confidence: 99%

Alcohol withdrawal delirium - diagnosis, course and treatment

Mainerova

Praško²,

Látalová³

et al. 2015

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub

View full text Add to dashboard Cite

A genome screen of maximum number of drinks as an alcoholism phenotype

et al. 2000

Self Cite

View full text Add to dashboard Cite

The Collaborative Study on the Genetics of Alcoholism (COGA) is a multicenter research program to detect and map susceptibility genes for alcohol dependence and related phenotypes. The measure M of "maximum number of drinks consumed in a 24-hour period" is closely related to alcoholism diagnosis in this dataset and provides a quantitative measure to grade nonalcoholic individuals. Twin studies have shown log(M) to have a heritability of approximately 50%. Genome screens for this trait were performed in two distinct genotyped samples (wave 1 and wave 2), and in the combined sample. MAPMAKER/SIBS was used to carry out Haseman-Elston based regression analyses. On chromosome 4, an unweighted all-pairs multipoint LOD of 2.2 was obtained between D4S2407 and D4S1628 in wave 1; in wave 2, the region flanked by D4S2404 and D4S2407 gave a LOD of 1.5. In the combined sample, the maximal LOD was 3.5 very close to D4S2407. This evidence for linkage is in the region of the alcohol dehydrogenase gene cluster on chromosome 4. These findings on chromosome 4 are consistent with a prior report from COGA in which strictly defined nonalcoholic subjects in wave 1 were analyzed. The present analysis on log(M) allows more individuals to be included and thus is potentially more powerful.

show abstract

The histories of withdrawal convulsions and delirium tremens in 1648 alcohol dependent subjects

Cited by 132 publications

References 45 publications

Recognition and Management of Withdrawal Delirium (Delirium Tremens)

Recognition and Management of Withdrawal Delirium (Delirium Tremens)

Alcohol withdrawal delirium - diagnosis, course and treatment

A genome screen of maximum number of drinks as an alcoholism phenotype

Contact Info

Product

Resources

About