The Human Plasma Proteome: History, Character, and Diagnostic Prospects

Abstract

FIG. 3. Reference intervals for 70 protein analytes in plasma.Abundance is plotted on a log scale spanning 12 orders of magnitude. Where only an upper limit is quoted, the lower end of the interval line shows an arrowhead. The classical plasma proteins are clustered to the left (high abundance), the tissue leakage markers (e.g. enzymes and troponins) are clustered in the center, and cytokines are clustered to the right (low abundance). Hemoglobin is included (far left) for comparison. Data were obtained from the Specialty Laboratories publications (154). TPA, tissue plasminogen activator; GCSF, granulocyte colony-stimulating factor; TNF, tumor necrosis factor. Additions & CorrectionsWe suggest that subscribers photocopy these corrections and insert the photocopies at the appropriate places where the article to be corrected originally appeared. Authors are urged to introduce these corrections into any reprints they distribute. Secondary (abstract) services are urged to carry notice of these corrections as prominently as they carried the original abstracts.

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