The hypoglycemic potential of phenolics from functional foods and their mechanisms

Головинская, Оксана; Wang, Chin‐Kun

doi:10.1016/j.fshw.2022.10.020

Cited by 44 publications

(20 citation statements)

References 248 publications

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“…Polyphenols in the diet have various health benefits. These compounds are associated with improved lipid profiles, blood pressure, insulin performance, and even the gut microbiome [ 14 , 31 ]. Polyphenols are also reported to lower cardiovascular health risks (i.e., myocardial infraction, stroke, and diabetes) [ 31 ].…”

Section: Resultsmentioning

confidence: 99%

“…Substitution of legumes has been acknowledged to offer various benefits, i.e., protein enrichment, texture improvement, satiety improvement, and positive alteration of the glycemic profile, lipidemic profile, and gut microbiota [ 12 , 13 ]. Legumes contain significant amounts of protein, fiber, and various secondary compounds, like phenolic compounds, that might provide various health benefits [ 14 ]. Indonesia preserves abundant biodiversity, including legume diversity [ 15 ].…”

Section: Introductionmentioning

confidence: 99%

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Kidney Bean Substitution Ameliorates the Nutritional Quality of Extruded Purple Sweet Potatoes: Evaluation of Chemical Composition, Glycemic Index, and Antioxidant Capacity

Palupi

Delina

Nurdin

et al. 2023

Foods

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The extrusion process may influence the nutritional profiles of carbohydrate-rich food ingredients, including the glycemic index (GI) and antioxidant capacity. This study aimed to evaluate the nutritional profile of extruded purple sweet potato (EPSP) substituted with kidney bean flour (KBF) (0, 30, and 40%). These foods were further characterized by their proximate composition, resistant starch, polyphenols, GI, and antioxidant capacities. The 40% KBF substitution enhanced the protein and fiber contents of the EPSP by up to 8% and 6%, respectively. Moreover, it also revealed that EPSP with 40% KBF substitution had a low-GI category (53.1), while the 0 and 30% substitution levels had a high-GI category, i.e., 77.4 and 74.7, respectively. However, the extrusion processing reduced the anthocyanin content and antioxidant capacity of purple sweet potato flour containing 40% KBF by 48% and 19%, respectively. There was a significant relationship between the GI values of proteins, fats, and fibers (p < 0.05). The insignificant effect of resistant starch and phenol contents on GI value was recorded due to the low concentrations of those components. KBF substitution could ameliorate the profile of protein, fiber, and GI, but not for antioxidant capacity. The other innovative processes for preserving antioxidant capacity might improve the product quality.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Kidney Bean Substitution Ameliorates the Nutritional Quality of Extruded Purple Sweet Potatoes: Evaluation of Chemical Composition, Glycemic Index, and Antioxidant Capacity

Palupi

Delina

Nurdin

et al. 2023

Foods

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“…Therefore, A. oryzae 001 may be degraded and reduced lipids in abalone viscera, resulting in lower total cholesterol levels in the fermented group than in the unfermented group. Hyperglycemia occurs due to abnormalities in glucose regulation, such as decreased glucose utilization, increased glucose production, and insulin secretion [ 32 ]. Since there were no significant differences in glucose concentrations among the study groups, it appears that abalone viscera consumption does not induce hyperglycemia.…”

Section: Resultsmentioning

confidence: 99%

Abalone Viscera Fermented with Aspergillus oryzae 001 Prevents Pressure Elevation by Inhibiting Angiotensin Converting Enzyme

Iwamoto

Sasaki

Maizawa³

et al. 2023

Nutrients

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Abalone viscera, which accounts for more than 20% of the total weight of abalone, is generally regarded as waste in the food industry, and effective methods are required to utilize it productively. In this study, the viscera were fermented with Aspergillus oryzae 001 to add functionality. Fermented abalone viscera exhibited increased angiotensin I-converting enzyme (ACE) inhibitory activity and enhanced inhibition of blood pressure elevation in spontaneously hypertensive rats (SHRs). Abalone viscera administration had no significant effect on body weight, food intake, liver and kidney weights, or serum components in SHRs. ACE inhibitors specific to fermented abalone viscera were identified through extraction, fractionation, purification, and analysis. The identified substance was L-m-tyrosine, which non-competitively inhibited ACE and, in a single oral administration, significantly reduced blood pressure in SHRs compared to that in the control. This study identified that abalone viscera fermented by A. oryzae 001 has an inhibitory effect on blood pressure elevation, suggesting its potential use as a functional food. In addition, L-m-tyrosine, a unique substance in fermented abalone viscera, was isolated for the first time as a single ACE-inhibitory amino acid.

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“…Other studies with caco-2 cells indicate that the phytochemicals, such as polyphenols and tannins, have the capacity to suppress glucose uptake in intestinal cells, by the inhibition of SGLT1. [75][76][77] In addition, reduced SGLT1 in the intestine increases the glucose available for metabolisation by the gut microbiota in the colon, where it reduces the colonic pH, thus increasing SCFA production and gut health. 74,78 In our study, plasma glucose was reduced by the consumption of cooked whole germinated millet flour.…”

Section: Papermentioning

confidence: 99%

Germinated and non-germinated cooked whole millet (Pennisetum glaucum (L.) R. Br.) flours show a promising effect on protein quality, biochemical profile and intestinal health in vivo

Magalhães,

da Silva,

Grancieri

et al. 2023

Food Funct.

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The hypoglycemic potential of phenolics from functional foods and their mechanisms

Cited by 44 publications

References 248 publications

Kidney Bean Substitution Ameliorates the Nutritional Quality of Extruded Purple Sweet Potatoes: Evaluation of Chemical Composition, Glycemic Index, and Antioxidant Capacity

Kidney Bean Substitution Ameliorates the Nutritional Quality of Extruded Purple Sweet Potatoes: Evaluation of Chemical Composition, Glycemic Index, and Antioxidant Capacity

Abalone Viscera Fermented with Aspergillus oryzae 001 Prevents Pressure Elevation by Inhibiting Angiotensin Converting Enzyme

Germinated and non-germinated cooked whole millet (Pennisetum glaucum (L.) R. Br.) flours show a promising effect on protein quality, biochemical profile and intestinal health in vivo

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