Comparative Biology of the Normal Lung 2015
DOI: 10.1016/b978-0-12-404577-4.00035-7
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The Immune Basis of Allergic Lung Disease

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Cited by 6 publications
(5 citation statements)
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References 269 publications
(385 reference statements)
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“…IL-6 has been recognized as a cytokine involved in inflammation, but also as a cytokine with regenerative and anti-inflammatory properties [20]. However, interleukin-10 (IL-10) suppresses the activity of monocytes and macrophages activity, and downregulates secretion of selected cytokines, such as TNF-α and IL-6, which are involved in inflammatory processes [21]. IL-10 is secreted to limit the release of TNF-α and IL-6 and to decrease inflammatory responses [22].…”
Section: Introductionmentioning
confidence: 99%
“…IL-6 has been recognized as a cytokine involved in inflammation, but also as a cytokine with regenerative and anti-inflammatory properties [20]. However, interleukin-10 (IL-10) suppresses the activity of monocytes and macrophages activity, and downregulates secretion of selected cytokines, such as TNF-α and IL-6, which are involved in inflammatory processes [21]. IL-10 is secreted to limit the release of TNF-α and IL-6 and to decrease inflammatory responses [22].…”
Section: Introductionmentioning
confidence: 99%
“…Its primary function is to facilitate immune responses and dampen inflammation, also by downregulating pro-inflammatory cytokine secretion (e.g., TNF-α, IL-6, etc.) [52]. As a result, it may be a factor that influences anti-tumor and/or mucosal immune responses.…”
Section: Discussionmentioning
confidence: 99%
“…IL-12, produced primarily by monocytes and macrophages, stimulates the growth of NK cells (at least in part) and Th1 cells through binding to its receptor on these cells (50). The effect elicited by IL-18 resembles the effect of IL-12, possibly because they synergize (51).…”
Section: Il-12 and Il-18mentioning
confidence: 99%