The Impact of Acute Myocardial Infarction on Left Ventricular Systolic Function

Koçinaj, Dardan; Bakalli, Aurora; Gashi, Masar; Begolli, Luljeta; Berisha, Merita; Allma, Kocinaj; Berisha, Blerim; Krasniqi, Xhevdet

doi:10.5455/medarh.2011.65.207-209

Cited by 3 publications

(1 citation statement)

References 10 publications

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“…6 HF after MI is an important prognostic factor, with such patients showing prolonged hospital stays and higher in hospital mortality. 7,8 It also aids us deciding the mode of therapy, by choosing early invasive strategy for these patients. [9][10][11][12] In the developing nations where valvular heart disease was once the commonest cause for heart failure, a rapid surge in IHD incidence is expected to change the epidemiology of HF as well.…”

Section: Introductionmentioning

confidence: 99%

Myocardial Infarction; New Onset Heart Failure After Mi. Its Frequency and Factors Contributing It

Anjum

Rashid

Hussain

et al. 2017

TPMJ

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ABSTRACT… Objectives:To determine the frequency of new onset heart failure after acute myocardial infarction and factors contributing it. Methods: A total of 228 patients were studied for occurrence of new onset clinical heart failure within24 hours after admission with an acute Myocardial Infarction. Clinical parameters were used to diagnose heart failure. Various risk factors were analyzed which contributed to occurrence of heart failure after MI. Patients undergoing primary angioplasty were not included into this study as medical thrombolysis was the most common mode of therapy (in >90% of patients). Results: Among the 228 patients studied 77.2 %( 176) were males and 22.8 %(52) were females. Mean age of the population was 56.3(±12.1) years. Women were relatively older on presentation as compared to men (mean age 58.9±10.9yr vs 55.5±12.3yr). Similarly mean age for NSTEMI was higher as compared to STEMI (58.59±11.1 vs 54.2±12.6yr.). A total of36.8 %( 84) patients exhibited clinical signs of heart failure within24 hours of their admission. These patients tend to be older than patients without HF (mean age 60±11years vs 54±12 years). Females after MI showed a greater frequency for going into HF as compared to males (42.3% vs 35.2% respectively). Now regarding the association of HF with various factors it was seen that, having a previous history of MI was found to be the strongest factor associated with occurrence of HF, with HF being nearly three times more common in these patients (i.e. 73% vs 26.1%, p value < 0.05). The current type of MI on presentation also showed a direct relationship with HF, being highest in patients with NSTEMI (i.e. up to 50 %) followed by AWMI (35.5%) and lowest in inferior wall MI (p value < 0.05). Diabetes, hypertension and smoking also showed a higher but statistically nonsignificant relationship with HF development (41.2% vs 34.3%, 41% vs 32.2% and 44% vs 32% respectively p value > 0.05). The blood pressure on presentation however was significantly associated with HF in these patients. Patients having high BP (> 140/80) on presentation depicted an overall higher incidence of HF as compared to patients having BP equal to or less than 140/80 (45.2% vs 31.3% p value < 0.05). Conclusion: Heart failure is a fairly common entity after acute MI, being the commonest in patients suffering an NSTEMI. Previous history of an MI showed to be the strongest coexisting factor associated with HF. Key words:Heart failure. Myocardial infarction.

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Section: Introductionmentioning

confidence: 99%

Myocardial Infarction; New Onset Heart Failure After Mi. Its Frequency and Factors Contributing It

Anjum

Rashid

Hussain

et al. 2017

TPMJ

View full text Add to dashboard Cite

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Correlation between Left Ventricular Function with Functional Capacity in Post Infarct Myocard Patients with Heart Failure

Sudirman

Pikir

Rinjani

2020

IOP Conf. Ser.: Earth Environ. Sci.

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In myocardial infarct patient with heart failure, left ventricular (LV) function evaluation after myocardial infarction provides prognostic information. However, the relationship between exercise capacity and LV function has not been fully explored. This study aims to analyze the correlation of LV function with functional capacity in acute myocardial infarct patient with heart failure. From 33 patients who fulfilled the inclusion and exclusion criteria, treadmill and echocardiography were examined (LVEDd, myocardial performance index (MPI), E/E’ diastolic function, LV Stiffness). The results are then statistically analyzed using SPSS. The mean LV ejection fraction is 44.27 ± 9.0% by Teich, and 40.55 ± 8.3% by Biplane. The value of the global MPI function is (0.60-0.90). The average E/A ratio is 1.0 ± 0.5, deceleration time (DT) is > 220m / sec, and E / E ratio is 11.46 ± 5.82ms. The functional capacity value is 3.4 (1.1-8.4) METS. There is a significant positive correlation of LV systolic function and functional capacity and significant negative correlation between MPI and functional capacity in myocardial infarct patients with heart failure. Furthermore, there is a non-significant correlation between diastolic function and functional capacity.

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Correlation between Serum Galectin-3 Level with Wall Motion Score Index in Patients with ST-Segment Elevation Myocardial Infarction

Halid

Aminuddin

Dewi

2020

IOP Conf. Ser.: Earth Environ. Sci.

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The inflammatory process plays an essential role in the process of atherosclerosis and the response of ventricular recovery after myocardial infarction. Galectin-3 is a mediator derived from macrophages and endothelium that is actively involved in various aspects of the inflammatory cell behavior. Galectin-3 increases in the formation of fibrosis and scar, which is a maladaptive response to injury and infarction such as ST-segment elevation myocardial infarction (STEMI). Wall Motion Score Index (WMSI) is a semiquantitative visual assessment of the dynamic left ventricular wall. WMSI has an association with left ventricular ejection fraction in assessing prognosis after myocardial infarction. This study aimed to determine the correlation of increasing galectin-3 level with WMSI in STEMI patients. A cross-sectional study with purposive sampling was done. Galectin-3 levels were measured using R&D System ELISA Quantikine® Human galectin-3 Immunoassay with units ng/ml. WMSI measured by 2D-echocardiography. We enrolled a total of 35 STEMI patients, 28 (80%) were males. The result of measurement of galectin-3 levels in STEMI patients increase significantly (12,545±6,504 ng/mL) and moderate positive correlation with WMSI (r=+0,429, p=0.01). The result of the study showed there is a significant positive correlation between serum galectin-3 level with WMSI in STEMI patients.

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The Impact of Acute Myocardial Infarction on Left Ventricular Systolic Function

Cited by 3 publications

References 10 publications

Myocardial Infarction; New Onset Heart Failure After Mi. Its Frequency and Factors Contributing It

Myocardial Infarction; New Onset Heart Failure After Mi. Its Frequency and Factors Contributing It

Correlation between Left Ventricular Function with Functional Capacity in Post Infarct Myocard Patients with Heart Failure

Correlation between Serum Galectin-3 Level with Wall Motion Score Index in Patients with ST-Segment Elevation Myocardial Infarction

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