The Impact of Consanguinity Worldwide

Jaber, Lutfi; Halpern, Gabrielle J.; Shohat, Mordechai

doi:10.1159/000016130

Cited by 113 publications

(116 citation statements)

References 27 publications

Supporting

Mentioning

111

Contrasting

Unclassified

Order By: Relevance

“…The primary cause of infant death among Bedouins was congenital malformations (5.8 per 1,000 live births in 2010) (Belmaker 2010). The most important factor contributing to the increased rate of congenital malformations among Bedouins and subsequent infant morbidity and mortality is consanguineous marriages (Bittles 2001;Jaber et al 1998;Weitzman et al 2000;Bromiker et al 2004;Hamamy 2012). Consanguineous marriages are very common among the Bedouins, and the reported rate was 60.1 % in 1992 (Vardi-Saliternik et al 2002).…”

Section: Introductionmentioning

confidence: 99%

Prevalence of consanguineous marriages and associated factors among Israeli Bedouins

et al. 2014

Self Cite

View full text Add to dashboard Cite

The Bedouin population in Israel is a semi-nomadic traditional patriarchal society. Consanguineous marriages are very common, contributing to high rates of congenital malformations and genetic diseases, resulting in high infant mortality. Data on consanguineous marriages among Bedouins in Israel are limited. This study examined the current prevalence of consanguineous marriages and their determinants among Israeli Bedouins. One thousand two hundred ninety Bedouin women who delivered in the maternity wards of the only hospital serving the Bedouin population were interviewed between November 2009 and January 2010. The prevalence of consanguineous marriages was 44.8 %.The most common type of spousal relationship was first cousins (65.7 % of all consanguineous marriages). The mean inbreeding coefficient was 0.0238. Factors significantly associated with consanguinity were less years of schooling (OR 0.94, 95 % CI (0.88-0.99), p=0.02) and younger age at marriage of the wife (OR 0.90, 95 % CI (0.80-0.96), p= 0.0002). In conclusion, the rate of consanguineous marriages among Bedouins is very high, making this population at risk for congenital malformations and genetic diseases. Efforts should be directed at better education and provision of premarital and prenatal counseling on the health consequences of consanguineous marriages and the possibilities to lower those risks.

show abstract

Section: Introductionmentioning

confidence: 99%

Prevalence of consanguineous marriages and associated factors among Israeli Bedouins

et al. 2014

Self Cite

View full text Add to dashboard Cite

show abstract

“…There are thus many reasons, both at a societal level and at an individual level, to aim for a modernization of the mate choice in groups that currently maintain a traditional consanguineous marriage tradition for a longterm social change. A similar genetic persistence of economic disadvantages might also exist on a macroeconomic level (Jaber et al, 1998), where some countries or regions carry a heavier burden of genetic disease through widespread kin marriage or small founder populations with limited genetic exchange (Bittles et al, 1991;Rudan et al, 2006;Verma, 2000).…”

Section: Self-perpetuating Marginalization and Genetic Self-mutilationmentioning

confidence: 92%

Applied cultural and social studies are needed for a sustainable reduction of genetic disease incidence

Staal

2017

European Journal of Sociology and Anthropology

View full text Add to dashboard Cite

While clinical and basic biomedical research focus on diagnoses and cures for common and rare genetic diseases, they are unable to address one of the largest underlying causes for genetic disease: mating within families or other small genetically isolated sub-populations. This interdisciplinary literature study investigates theoretical, moral and practical aspects to solve this major cause for genetic disease from an alternative angle: through cultural change and encouragement of an outbreeding reproductive behavior. Understanding why some communities persist with choosing consanguineous reproductive partners when the modern society has eliminated the economic rationale to do so, and to develop strategies to encourage a cultural change in those communities, is critical for a sustainable long-term solution to reduce the number of new cases of genetic disease and undiagnosed (sub-clinical) but detrimental genetic abnormalities in vulnerable and marginalized groups in modern Western societies.

show abstract

“…Additional studies conducted by, [14,[50][51][52]. verified that, the increased risk for a significant birth defect in offspring of a first cousin union range between 1.7 and 2.8% above the risk of the general population risk.…”

Section: Consanguinity Is a Genetics Dilemma And A Social Problemmentioning

confidence: 93%

Consanguineous Marriages in the Middle East: Nature Versus Nurture

Bowirrat¹,

Zaher²

2014

TOALTMEDJ

View full text Add to dashboard Cite

Abstract:Family is societal institution that is conceptualized as "Vital" and "Valid" its importance is emphasized by social conservatives across cultures. Consanguinity is usually socially motivated and can be genetically harmful; it is a state of being descended from a common ancestor. It has been practiced by many societies around the globe from time immemorial, and a part of most civilizations as far back as the Old Testament of the Bible, and in the Arab world before the emerging of the Islam, and therefore, it is not monopoly where Islamic faith prevails.We scrutinize the effect of consanguinity on family health, its benefits and its detriments, and how should be tackled on medical and policy levels. We also pursue the Islamic attitude and discourses on the marriage custom, law, ethics and principles. Attention is then drawn to the cultural influences and challenges in the Arab word.

show abstract

The Impact of Consanguinity Worldwide

Cited by 113 publications

References 27 publications

Prevalence of consanguineous marriages and associated factors among Israeli Bedouins

Prevalence of consanguineous marriages and associated factors among Israeli Bedouins

Applied cultural and social studies are needed for a sustainable reduction of genetic disease incidence

Consanguineous Marriages in the Middle East: Nature Versus Nurture

Contact Info

Product

Resources

About