The impact of HIV testing on blood utilization in the intensive care unit in patients with gastrointestinal bleeding

Me, Ravry; Hl, Paz

doi:10.1007/bf01712335

Cited by 6 publications

(2 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This massive drop in use is most likely due to the increasing awareness about the safety of blood transfusion, particularly the general public's unease and worry about the transmission of HIV by blood transfusion. This HIV “scare” seems to have been widespread among both patients and their treating physicians since the early nineties, which significantly impacted the practice of hemotherapy 23, 24, 25. We have recently reported a similar trend in a long-term survey of the use of packed red blood cells 26 …”

Section: Discussionmentioning

confidence: 72%

Long-term audit of the use of fresh frozen plasma in a university hospital

Gader

Al-Ghumlas

Momen

et al. 2017

Journal of Taibah University Medical Sciences

View full text Add to dashboard Cite

Objectives There is universal concern about the inappropriate use of fresh frozen plasma (FFP). This study aimed to determine the extent of the inappropriate use of FFP at a university hospital in KSA. Methods Medical records on the annual use of FFP were analysed from 1986 to 2007. Then, the results of the coagulation screening tests were extracted from the medical records of 531 consecutive patients in various departments of the hospital. Results As many as 68,480 FFP units were used during the 22 year study period. Consumption increased and then plateaued in 1995, but dropped dramatically by 30.9% and reached its lowest level in 2000. There was also a concomitant and overlapping drop in both FFP usage and the hospital mortality rate per patient admission. One-thousand-six-hundred-twenty FFP units were issued for 531 patients. Coagulation testing, before and after infusion, was adopted in almost all patients in the Department of Obstetrics and Gynaecology, in 90% of patients in the Department of Surgery and in approximately 70% of patients in other departments. Conclusions Significant inappropriate use of FFP at our institute has been made evident by examining the remarkable drop in use following the universal “HIV scare” of the early 1990s. The resulting drop in the hospital mortality rate, accompanying the simultaneous drop in FFP use, reflects the benefits of resorting to the use of less blood therapy. Coagulation testing was used to a satisfactory extent. Transfusion audits and educational programs could result a better use of FFP.

show abstract

Section: Discussionmentioning

confidence: 72%

Long-term audit of the use of fresh frozen plasma in a university hospital

Gader

Al-Ghumlas

Momen

et al. 2017

Journal of Taibah University Medical Sciences

View full text Add to dashboard Cite

show abstract

“…Although there is some suggestion that doctors have been influenced in their prescribing habits by the risk of HIV transmission through blood transfusions, resulting in transfusion at lower Hb levels than before [80], it is unclear whether the prescribing habits of physicians are influenced by a patient’s HIV status, i.e. how rigorously is the cause of the underlying anaemia investigated, is proper informed consent taken and is this application of good transfusion practice [81] dependent on the patient’s HIV status.…”

Section: Discussionmentioning

confidence: 99%

The impact of HIV-associated anaemia on the incidence of red blood cell transfusion: Implications for blood services in HIV-endemic countries

Berg¹,

Murphy²,

Pretorius³

et al. 2014

Transfusion and Apheresis Science

View full text Add to dashboard Cite

Cytopaenias, especially anaemia, are common in the HIV-infected population. The causes of HIV related cytopaenias are multi-factorial and often overlapping. In addition, many of the drugs used in the management of HIV-positive individuals are myelosuppresive and can both cause and exacerbate anaemia. Even though blood and blood products are still the cornerstone in the management of severe cytopaenias, how HIV may affect blood utilisation is not well understood. The impact of HIV/AIDS on blood collections has been well documented. As the threat posed by HIV on the safety of the blood supply became clearer, South Africa introduced progressively more stringent donor selection criteria, based on the HIV risk profile of the donor cohort from which the blood collected. The implementation of new testing technology in 2008 which significantly improved the safety of the blood supply enabled the removal of what was perceived by many as a racially based donor risk model. However, this new technology had a significant and sustained impact on the cost of blood and blood products in South Africa. In contrast, it would appear little is known of how HIV influences the utilisation of blood and blood products. Considering the high prevalence of HIV among hospitalised patients and the significant risk for anaemia among this group, there would be an expectation that the transfusion requirements of an HIV-infected patient would be higher than that of an HIV-negative patient. However, very little published data is available on this topic which emphasises the need for further large-scale studies to evaluate the impact of HIV/AIDS on the utilisation of blood and blood products and how the large-scale roll-out of ARV programs may in future play a role in determining the country’s blood needs.

show abstract

The Role of Blood Substitutes in Emerging Healthcare Systems

Winslow

1998

Blood Substitutes, Present and Future Perspectives

View full text Add to dashboard Cite

The impact of HIV testing on blood utilization in the intensive care unit in patients with gastrointestinal bleeding

Cited by 6 publications

References 12 publications

Long-term audit of the use of fresh frozen plasma in a university hospital

Long-term audit of the use of fresh frozen plasma in a university hospital

The impact of HIV-associated anaemia on the incidence of red blood cell transfusion: Implications for blood services in HIV-endemic countries

The Role of Blood Substitutes in Emerging Healthcare Systems

Contact Info

Product

Resources

About