2018
DOI: 10.1093/jcag/gwy053
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The Impact of Inflammatory Bowel Disease in Canada 2018: Extra-intestinal Diseases in IBD

Abstract: The burden of extra-intestinal disease is high in patients with IBD, some of whom respond to or are prevented by treating the bowel inflammation, whereas others require specific treatment because they are independent of the underlying bowel inflammation. Among the most common extra-intestinal manifestations are other chronic immune-mediated diseases such as erythema nodosum, ankylosing spondylitis and primary sclerosing cholangitis. Patients with IBD are at higher risk of complications in other organ systems s… Show more

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Cited by 69 publications
(52 citation statements)
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“…Even with the wide evidence base on the bi-directionality of the brain–gut axis, the question often arises: Which came first: the brain or the gut? Paying homage to the biomedical model, it is often assumed that psychological difficulties are a cause of functional gut disorders [ 1 ] and are co-morbid with organic gut disorders such as inflammatory bowel disease [ 33 ]. Co-morbidity assumes that two diseases are present—gut disorder and psychiatric disorder—which are largely independent of each other and require independent treatments.…”
Section: Psychogastroenterology: the Brain–gut Axismentioning
confidence: 99%
“…Even with the wide evidence base on the bi-directionality of the brain–gut axis, the question often arises: Which came first: the brain or the gut? Paying homage to the biomedical model, it is often assumed that psychological difficulties are a cause of functional gut disorders [ 1 ] and are co-morbid with organic gut disorders such as inflammatory bowel disease [ 33 ]. Co-morbidity assumes that two diseases are present—gut disorder and psychiatric disorder—which are largely independent of each other and require independent treatments.…”
Section: Psychogastroenterology: the Brain–gut Axismentioning
confidence: 99%
“…Для Пс, ПсА и ВЗК общими являются: снижение повседневной активности, трудоспособности, качества жизни; психологические нарушения (в том числе тревога и депрессия); коморбидная патология (метаболические нарушения, сахарный диабет, заболевания сердечно-сосудистой системы, атеросклероз); снижение продолжительности жизни по сравнению с общей популяцией [10][11][12][13][14][15][16][17][18][19].…”
Section: процесс формирования согласительных рекомендацийunclassified
“…Based on other models of chronic inflammation, for patients with a newly diagnosed vascular event, current standards of therapy—including warfarin, heparin, aspirin, thrombolysis, surgical thrombectomy and arterial stents—are indicated [ 42 , 43 ]. The new generation of anticoagulants, including melagatran/ximelagatran and fondaparinux, are currently under evaluation for use in IBD patients with thrombotic events [ 44 ].…”
Section: Introductionmentioning
confidence: 99%