The impact of lifestyle factors on evolution of atopic dermatitis: An alternative approach (Review)

Solomon, Iulia; Ilie, Mihaela; Drăghici, Carmen; Voiculescu, Vlad Mihai; Căruntu, Constantin; Boda, Daniel; Zurac, Sabina

doi:10.3892/etm.2018.6980

Cited by 35 publications

(48 citation statements)

References 78 publications

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“…Another mechanism implicated in DA is the dysfunction of the epidermal barrier. By disrupting this barrier, antigens can penetrate the skin and generate the production of inflammatory cytokines that support the underlying mechanism of the pathology (1).…”

Section: Introductionmentioning

confidence: 99%

Correlation between quality of life and disease severity of pediatric patients with atopic dermatitis

et al. 2020

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Atopic dermatitis (AD) is a complex, chronic skin disorder with a broad spectrum of clinical aspects, characterized by abnormal skin barrier function. This has a significant impact on patients' quality of life (QoL), which represents a crucial parameter for their wellbeing. This study assessed the QoL of patients with AD by following parameters such as itching, disturbance of sleep, disturbance of play activity, and community activities. The study included 64 patients clinically diagnosed with AD, aged 0 to 16 years. QoL of patients with AD was measured by evaluating the QoL indices for infants and young children (IDQoL-Infants' Dermatitis Quality of Life Index) and the QoL for children over 4 years (CDQoL-Children's Dermatology Life Quality Index). The severity of the disease was also monitored by evaluating the SCORAD index. The major symptom for atopic dermatitis, pruritus, was found most frequently in our study and influenced patients' QoL. The study showed that the above questionnaires are efficient tools for correlating AD severity with QoL even in younger patients and could be included in current guidelines. This is the first study that analyzed the QoL of pediatric patients with atopic dermatitis in Romania and can constitute the basis for elaborating a more comprehensive disease management guidelines.

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Section: Introductionmentioning

confidence: 99%

Correlation between quality of life and disease severity of pediatric patients with atopic dermatitis

et al. 2020

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“…Finally, we have not taken into consideration in this analysis other photoprotection measures different from sunscreen (clothes, avoidance sun exposure) or sedentary lifestyle that could also influence serum VD levels and perhaps AD severity. 40 In conclusion, although serum 25(OH)D levels in AD patients were comparable to those of healthy controls, disease severity was inversely associated with serum 25(OH)D levels in patients with light phototypes. For those with dark phototypes, this association was only detected for those with markers of allergy.…”

Section: Studies Of the Relationship Between Other Atopic Diseases Anmentioning

confidence: 70%

“…Another limitation of the study is that patients with AD were recruited in pediatrics and dermatology clinics; therefore, children with mild AD can be underrepresented. Finally, we have not taken into consideration in this analysis other photoprotection measures different from sunscreen (clothes, avoidance sun exposure) or sedentary lifestyle that could also influence serum VD levels and perhaps AD severity …”

Section: Discussionmentioning

confidence: 99%

The association between atopic dermatitis and serum 25‐hydroxyvitamin D in children: Influence of sun exposure, diet, and atopy features—A cross‐sectional study

Sanmartín¹,

Pardos

Doste³

et al. 2020

Pediatric Dermatology

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Background Previous studies have linked low serum vitamin D (VD) or 25‐hydroxyvitamin D (25(OH)D) levels with increased severity of atopic dermatitis (AD) in children. Objective To investigate the association between serum VD (25(OH)D) levels and AD and AD severity, considering the influence of diet and sun exposure. Methods We performed a prospective cross‐sectional study of healthy controls and children diagnosed with AD. Participants were recruited between January 2011 and December 2012, and the following parameters were assessed: age, sex, body mass index (BMI), AD severity, Fitzpatrick skin type, asthma and rhinitis history, dietary VD intake, daily potential sun‐induced VD production, sunscreen use, 25(OH)D and IgE serum levels, and results of the ImmunoCAP Phadiatop Infant test. Results The study population consisted of 105 healthy controls and 134 AD patients. Serum 25(OH)D levels were significantly lower in moderate and severe AD than in mild AD, although this association was only significant for patients with light Fitzpatrick skin type (mean(SD) 36.7 (11.9) ng/mL; moderate 28.8 [11.5] ng/mL; and severe 27.6 [12.1] ng/mL, P = .045). Logistic regression analysis revealed a positive association between severe AD and both positive ImmunoCAP Phadiatop test and BMI. Conclusion Our data support an association between VD deficiency and AD severity only in patients with light complexion.

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“…Atopic dermatitis falls into suicide risk dermatological diseases. In the spring, exacerbation of atopic conditions may increase the risk of suicide (36,37). Halvorsen et al (38) reported the presence of suicidal ideation in 15.5% of those studied with dermatitis vs. 9.1% of those who did not have dermatitis.…”

Section: Dermatological Conditions With Increased Risk Of Suicidal Bementioning

confidence: 99%

Assessment of suicidal behavior in dermatology (Review)

et al. 2019

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Many diseases that affect physical health can also affect mental health. Many of these diseases are studied in terms of quality of life, depression and suicidal behavior. Dermatological disorders, although having a strong impact on the individual's life, are less studied with regard to suicidal behavior. There is a need to approach several dermatological diseases from the perspective of suicidal behavior in order to intervene early with specific treatment or to prevent suicide. Psoriasis, acne, melanoma, atopic dermatitis and urticaria are scarcely studied from the point of view of suicidal behavior. In addition to these diseases, there are others that require attention in terms of suicidal behavior, such as vitiligo or oculocutaneous albinism, most probably due to a small number of people suffering from these diseases, research is almost non-existent in these cases. We want to draw attention to the importance of early detection of suicidal behavior in dermatological practice and to highlight the need for several studies on this subject. Contents 1. Introduction 2. Suicide in dermatology 3. Aspects of suicidal risk assessment in patients with dermatological diseases 4. Dermatological conditions with increased risk of suicidal behavior 5. Conclusions

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The impact of lifestyle factors on evolution of atopic dermatitis: An alternative approach (Review)

Cited by 35 publications

References 78 publications

Correlation between quality of life and disease severity of pediatric patients with atopic dermatitis

Correlation between quality of life and disease severity of pediatric patients with atopic dermatitis

The association between atopic dermatitis and serum 25‐hydroxyvitamin D in children: Influence of sun exposure, diet, and atopy features—A cross‐sectional study

Assessment of suicidal behavior in dermatology (Review)

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