2016
DOI: 10.1016/j.clnu.2015.08.005
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The impact of sarcopenia and myosteatosis on outcomes of unresectable pancreatic cancer or distal cholangiocarcinoma

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Cited by 174 publications
(198 citation statements)
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“…19,21 Furthermore, in interpreting the SM area on a single CT slice, myosteatosis, which is interpreted as fatty infiltration in skeletal muscle, might be exclusively considered to evaluate the function of SM deliberately. 22,33,34 …”
Section: Discussionmentioning
confidence: 99%
“…19,21 Furthermore, in interpreting the SM area on a single CT slice, myosteatosis, which is interpreted as fatty infiltration in skeletal muscle, might be exclusively considered to evaluate the function of SM deliberately. 22,33,34 …”
Section: Discussionmentioning
confidence: 99%
“…Sarcopenia and myosteatosis have been significantly associated with a range of adverse outcomes including increased rate of post‐operative complications,10, 11, 40, 41, 42 longer length of hospital stay,41, 43 30‐day post‐operative mortality and in‐hospital mortality,44 and dose‐limiting toxicities 5, 6, 7, 8, 45, 46, 47, 48, 49, 50. In addition, the conditions have been demonstrated as independent predictors of reduced overall survival 18, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64. The situation is further complicated by the obesity epidemic that has been progressively worsening in recent times.…”
Section: Discussionmentioning
confidence: 99%
“…Increased fat content in muscle tissue (myosteatosis) also seems to impact clinical outcome in pancreatic cancer. In fact, there are indications that increased muscle fat content rather than low muscle mass is associated with shorter survival in patients with unresectable pancreatic cancer . CT scans contain information about the radio density of a specific tissue type in Hounsfield units (HUs), which is referred to as radiation attenuation.…”
Section: Introductionmentioning
confidence: 99%