Background: An 8-hour shift system with faster rotation (e.g., shift changes every 2 to 5 days) is common for nurses at acute hospitals in Korea. However, there is a lack of information regarding nurses’ perceptions and experiences of rotating shift schedules, as well as the ways in which rotating-shift work affects patient outcomes. This study aimed to identify and describe emergent themes and offer new insights into nurses’ perceptions and experiences of rotating-shift work in Korea. Moreover, it explored the relationship between rotating-shift work and nurse and patient outcomes.Methods: A qualitative descriptive design was employed. Focus group interviews were conducted with 24 rotating-shift nurses at Korean acute care hospitals. Qualitative data were collected between January and February 2019, and conventional content analysis was employed. Results: Three themes and eight subthemes emerged. Major themes were unsatisfactory work schedules, the impact of shift work on nurses' lives, and the impact of schedule-related fatigue on overall work performance.Conclusion: Study findings highlight the importance of optimal scheduling, to reduce fatigue among rotating-shift nurses. Managers and administrators may improve nurse performance and patient safety by reviewing scheduling practices, considering the potential impact of shift schedules on nurse and patient outcomes, and addressing nurse’s scheduling issues. Furthermore, hospital authorities should consider revising schedules to include sufficient breaks between shifts. This study addressed issues that stem from rotating shift work, affecting both nurses and patients. Nurse interviews clarified these issues, which were classified according to theme. This study aimed to find practical solutions for shift planning problems, particularly in Korea, and to inform the development of scheduling guidelines for rotating-shift work in the future.