The importance of this research focused on the adaptation to online learning, since traditionally a face-to-face education was developed for university students, but the transition to an asynchronous education, with the needs and development of university students have changed, such as: learning resources, academic mentoring, and teaching didactics, the satisfaction of what is learned, the virtual platform used to study to identify their changes and others. The purpose of this study was to recognize the factors that influence asynchronous learning in the academic satisfaction of the students of the professional career of Administration of the San Luis Gonzaga National University, presenting the theoretical constructs as well as the results of the research that preceded us, both international and national, within the scheme of a curriculum based on professional competencies. The methodology of the study focused on basic quantitative research that allowed a correlational study in order to analyze the factors of distance learning of the 618 students that were part of the population, and to obtain the information from the students, a questionnaire of 23 questions was applied. Subsequently, current statistical tools were used, and the research findings were important in considering that the research objectives were validated, and the hypotheses were contrasted, where online learning is significantly related to the academic satisfaction of the students.