The impact of the alveolar bone sites on early implant failure: a systematic review with meta-analysis

Fouda, Amr

doi:10.5125/jkaoms.2020.46.3.162

Cited by 16 publications

(11 citation statements)

References 44 publications

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“…Early implant losses in dental implantology are reported in the literature between 0.5% and 3% 16,17 . In the present study, there was no early loss; the implant success rate was 100% during the observation period.…”

Section: Discussionsupporting

confidence: 56%

Tooth shell technique: A proof of concept with the use of autogenous dentin block grafts

Korsch

2021

Australian Dental Journal

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Background: Autogenous bone block graft is considered the gold standard for lateral bony defects. Dentin has been identified to be a suitable autogenous bone graft material due to its structural and chemical similarities to the alveolar bone. Methods: This proof of concept study describes the clinical application of the tooth shell technique in 24 sites with 27 implants of 22 patients. A tooth shell was fixed laterally to the defect with microscrews. Distance between the shell and the residual bone was filled with particulate remnants of the tooth root. Implant was inserted simultaneously. Cone beam computed tomography was done after implant insertion (T1) and 3 months later at time of implant exposure (T2). Target parameters were biological complications and the resorption of hard tissue graft. Results: Even though a graft exposure occurred in one case (4.5% on patient-level), all implants showed enough implant stability and were able to be loaded. At T2, the evaluation of the X-rays showed no case with hard tissue loss at the mesial or distal implant shoulder. All implants were completely osseointegrated. Conclusions: The tooth shell technique showed promising results for the reconstruction of lateral alveolar crest defects. It may be considered to serve as an alternative material to avoid bone harvesting procedures.

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Section: Discussionsupporting

confidence: 56%

Tooth shell technique: A proof of concept with the use of autogenous dentin block grafts

Korsch

2021

Australian Dental Journal

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“…Dental implants are widely used in the treatment of edentulism. Peri-implantitis, with a prevalence ranging from 1.1% to 85% at the implant level and a higher early failure rate in maxillary implants than mandibular implants, occurs in the peri-implant region and often leads to inflammatory loss of supporting bone ( 188 , 271 , 272 ). Radiographic bone loss greater than or equal to 2 mm beyond the crestal bone level from the initial surgery, or greater than or equal to 3 mm apical to the most coronal part of the intraosseous portion of the implant is observed in peri-implantitis, with even greater progression than that in periodontitis ( 273 ).…”

Section: Inflammasomes In Inflammatory Osteolysis Of the Alveolar Bone And Jawsmentioning

confidence: 99%

Inflammasomes in Alveolar Bone Loss

2021

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Bone remodeling is tightly controlled by osteoclast-mediated bone resorption and osteoblast-mediated bone formation. Fine tuning of the osteoclast–osteoblast balance results in strict synchronization of bone resorption and formation, which maintains structural integrity and bone tissue homeostasis; in contrast, dysregulated bone remodeling may cause pathological osteolysis, in which inflammation plays a vital role in promoting bone destruction. The alveolar bone presents high turnover rate, complex associations with the tooth and periodontium, and susceptibility to oral pathogenic insults and mechanical stress, which enhance its complexity in host defense and bone remodeling. Alveolar bone loss is also involved in systemic bone destruction and is affected by medication or systemic pathological factors. Therefore, it is essential to investigate the osteoimmunological mechanisms involved in the dysregulation of alveolar bone remodeling. The inflammasome is a supramolecular protein complex assembled in response to pattern recognition receptors and damage-associated molecular patterns, leading to the maturation and secretion of pro-inflammatory cytokines and activation of inflammatory responses. Pyroptosis downstream of inflammasome activation also facilitates the clearance of intracellular pathogens and irritants. However, inadequate or excessive activity of the inflammasome may allow for persistent infection and infection spreading or uncontrolled destruction of the alveolar bone, as commonly observed in periodontitis, periapical periodontitis, peri-implantitis, orthodontic tooth movement, medication-related osteonecrosis of the jaw, nonsterile or sterile osteomyelitis of the jaw, and osteoporosis. In this review, we present a framework for understanding the role and mechanism of canonical and noncanonical inflammasomes in the pathogenesis and development of etiologically diverse diseases associated with alveolar bone loss. Inappropriate inflammasome activation may drive alveolar osteolysis by regulating cellular players, including osteoclasts, osteoblasts, osteocytes, periodontal ligament cells, macrophages, monocytes, neutrophils, and adaptive immune cells, such as T helper 17 cells, causing increased osteoclast activity, decreased osteoblast activity, and enhanced periodontium inflammation by creating a pro-inflammatory milieu in a context- and cell type-dependent manner. We also discuss promising therapeutic strategies targeting inappropriate inflammasome activity in the treatment of alveolar bone loss. Novel strategies for inhibiting inflammasome signaling may facilitate the development of versatile drugs that carefully balance the beneficial contributions of inflammasomes to host defense.

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“…There were no significant differences in success rates in relation of age, gender, and anatomic sites and guided implant surgery. On the contrary, previous studies [26][27][28] reported an early implant failure due to anatomical sites; especially anterior maxilla.…”

Section: Discussionmentioning

confidence: 78%

The Relationship between Implant Size and Success Rate in Computer Guided Implant Surgery

Younis¹,

Hantash²

2020

JBiSE

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Guided implant surgery gained acceptance and credit in implant dentistry. The aim of this study is to find out and evaluate the relationship between implant size and success rate following computed tomography scan guided implant surgery. Sixty-four (36 females, 28 males) completely and partially edentulous patients aged between 42 and 65 years old were participated and fulfilled the inclusion criteria of the study. Two hundred and seventeen dental implants (length: 10, 11.5, and 13 mm; Diameter: 3.3, 3.75, and 4.2 mm) were placed using computed tomography scan guided implant surgery, 117 implants were placed in the maxilla, while 100 implants were placed in the mandible. The implants were evaluated for clinical parameters at 2, 4, and 12 weeks intervals after installation. The overall success rate was 95.4%. Clinical stability of the implant size (Diameter 3.3 mm, Length 10 mm) was the least as compared to other dimensions (P ≤ 0.05). Medium and large size implants (Diameter 3.75 and 4.2 mm, Length 11.5 and 13 mm) were the highest success rate in implant surgery. Implants width (diameter 3.3 mm) and length (10 mm) are best avoided in guided computed tomography surgery as compared with other implant sizes especially in atrophic bony areas. Computer-guided implant surgery remains exciting. Watchful planning and precise stability of the surgical guide are mandatory for successful protocol. Further investigations should be performed to assess such technique among dental patients from satisfactory point of view. Intensive cooperation between dentists and software engineering discipline should be aimed to maximize the success of such technique.

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The impact of the alveolar bone sites on early implant failure: a systematic review with meta-analysis

Cited by 16 publications

References 44 publications

Tooth shell technique: A proof of concept with the use of autogenous dentin block grafts

Tooth shell technique: A proof of concept with the use of autogenous dentin block grafts

Inflammasomes in Alveolar Bone Loss

The Relationship between Implant Size and Success Rate in Computer Guided Implant Surgery

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