Introduction: Cancer disease has become the first cause of death in the United States and world-wide. Most Researchers estimate that 595,690 of American people will die from cancer at the end of the year 2017. That means 1,600 deaths/day approximately. Cancer in modern societies is commonly treated with the combination of organ surgery, chemotherapy and radiotherapy which has many side effects and the high possibility of metastasis. Many kinds of diet strategies have been experimented. However, none of them have been particularly effective.
Materials and Methods:According to Otto Warburg hypothesis in the 1930's, the cause of cancer is the change in the metabolism of mitochondrion in human cells. Low oxygen in tissues in combination with high blood glucose will change the cell respiration from aerobic to anaerobic which leads to fermentation type of respiration. Professor Thomas N Seyfried in 2012 proposed cancer as a metabolic-mitochondrial disease. He has mentioned that all cancer cells' mitochondria are damaged and do not work properly.Results: Mitochondrion is a microorganism living inside our cells and produce energy in the form of Adenosine Triphosphate (ATP) from fats, glucose and glutamine. In order to produce ATP, mitochondria need oxygen through the krebs cycle which is called "Aerobic Respiration". On the other hand, when the amounts of oxygen go under 30% in the tissues and cells, mitochondria cannot respire properly which causes the increase in the amounts of Reactive Oxygen Species (ROS) or better called "Inflammation" inside the cells and causes damage to the mitochondria. According to Professor Thomas N Seyfried, the main cause of cancer is the increase in ROS inside normal cells [Thomas N Seyfried et al., 2012].
Conclusion:In 2017 we (MAJ Dr. Sorush Niknamian and Professor Dr. Somayeh Zaminpira along with the continuous help of Professor Seyfried and Professor Stephanie Seneff hypothesized with the sponsorship of the Weston A. Price Foundation (WAPF), that cancer is an Evolutionary Metabolic Disease which we proposed in the 4 th International Conference in Medicine and Neurological Diseases which held in Fulda/Germany.